P42696: RNA-binding protein 34

General Information

Protein names	- RNA-binding protein 34 - RNA-binding motif protein 34
Gene names	RBM34
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P42696

9 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALEGMSKRK RKRSVQEGEN PDDGVRGSPP EDYRLGQVAS SLFRGEHHSR GGTGRLASLF
        70         80         90        100        110        120
SSLEPQIQPV YVPVPKQTIK KTKRNEEEES TSQIERPLSQ EPAKKVKAKK KHTNAEKKLA
       130        140        150        160        170        180
DRESALASAD LEEEIHQKQG QKRKNSQPGV KVADRKILDD TEDTVVSQRK KIQINQEEER
       190        200        210        220        230        240
LKNERTVFVG NLPVTCNKKK LKSFFKEYGQ IESVRFRSLI PAEGTLSKKL AAIKRKIHPD
       250        260        270        280        290        300
QKNINAYVVF KEESAATQAL KRNGAQIADG FRIRVDLASE TSSRDKRSVF VGNLPYKVEE
       310        320        330        340        350        360
SAIEKHFLDC GSIMAVRIVR DKMTGIGKGF GYVLFENTDS VHLALKLNNS ELMGRKLRVM
       370        380        390        400        410        420
RSVNKEKFKQ QNSNPRLKNV SKPKQGLNFT SKTAEGHPKS LFIGEKAVLL KTKKKGQKKS
       430
GRPKKQRKQK

Isoforms

- Isoform 2 of RNA-binding protein 34

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P42696-1-unknown	MALEGM...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P42696-1-unknown	MALEGM...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87120
P42696-2-acetylation	ALEGMS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P42696-2-acetylation	ALEGMS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P42696-2-acetylation	ALEGMS...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162942
P42696-3-unknown	LEGMSK...	3		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000400000
P42696-3-unknown	LEGMSK...	3		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt131946
P42696-6-unknown	MSKRKR...	6		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000355565
P42696-6-unknown	MSKRKR...	6		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt131948
P42696-14-	SVQEGE...	14			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P42696-14-	SVQEGE...	14			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P42696-14-unknown	SVQEGE...	14		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169791
P42696-127-unknown	ASADLE...	127		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14124
P42696-127-unknown	ASADLE...	127		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143765
P42696-156-unknown	KILDDT...	156		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10078
P42696-156-unknown	KILDDT...	156		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144981
P42696-178-unknown	EERLKN...	178		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11517
P42696-178-unknown	EERLKN...	178		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145845

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RESALA	126	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14124
...RESALA	126	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127007
...KVADRK	155	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10078
...KVADRK	155	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128261
...QINQEE	177	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11517
...QINQEE	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129142
...EERLKN	182	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000413409
...EERLKN	182	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112794
...QRKQK	430	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	126	SALA.\|.ASAD	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAA_HUMAN	155	ADRK.\|.KILD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	177	NQEE.\|.EERL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)