Q9BTM1: Histone H2A.J

General Information

Protein names	- Histone H2A.J - H2a/j
Gene names	H2AFJ
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BTM1

7 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGRGKQGGK VRAKAKSRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YLAAVLEYLT
        70         80         90        100        110        120
AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK

TESQKTKSK

Isoforms

- Isoform 2 of Histone H2A.J

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9BTM1-2-unknown	MSGRGK...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9BTM1-2-unknown	MSGRGK...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BTM1-1-unknown	MSGRGK...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76691
Q9BTM1-2-Acetylation	SGRGKQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BTM1-2-Acetylation	SGRGKQ...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111594
Q9BTM1-2-Acetylation	SGRGKQ...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9BTM1-22-unknown	AGLQFP...	22		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10515
Q9BTM1-22-unknown	AGLQFP...	22		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt136965
Q9BTM1-60-unknown	TAEILE...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10517
Q9BTM1-60-unknown	TAEILE...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14946
Q9BTM1-60-unknown	TAEILE...	60		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139879
Q9BTM1-61-unknown	AEILEL...	61		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10519
Q9BTM1-61-unknown	AEILEL...	61		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139968
Q9BTM1-83-unknown	HLQLAI...	83		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10521
Q9BTM1-83-unknown	HLQLAI...	83		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141456

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SRSSRA	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10515
...SRSSRA	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt119793
...VLEYLT	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10517
...VLEYLT	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14946
...VLEYLT	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122984
...LEYLTA	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10519
...LEYLTA	60	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123074
...RIIPRH	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10521
...RIIPRH	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124630
...KTKSK	129	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	21	SSRA.\|.AGLQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	59	EYLT.\|.TAEI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	59	EYLT.\|.TAEI	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAA_HUMAN	60	YLTA.\|.AEIL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	82	IPRH.\|.HLQL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)