Q16778: Histone H2B type 2-E

General Information

Protein names	- Histone H2B type 2-E - Histone H2B-GL105 - Histone H2B.q - H2B/q
Gene names	HIST2H2BE
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16778

7 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPEPAKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSI YVYKVLKQVH PDTGISSKAM
        70         80         90        100        110        120
GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR LLLPGELAKH AVSEGTKAVT

KYTSSK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q16778-2-unknown	MPEPAK...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q16778-2-Acetylation	PEPAKS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q16778-6-unknown	KSAPAP...	6		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14543
Q16778-13-unknown	KGSKKA...	13		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10330
Q16778-22-unknown	AQKKDG...	22		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10331
Q16778-53-unknown	TGISSK...	53		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12406
Q16778-59-unknown	AMGIMN...	59		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10332

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MPEPAK	5	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14543
...APAPKK	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10330
...KAVTKA	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10331
...QVHPDT	52	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12406
...GISSKA	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10332
...YTSSK	126	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	5	EPAK.\|.KSAP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAA_HUMAN	12	APKK.\|.KGSK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	21	VTKA.\|.AQKK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	52	HPDT.\|.TGIS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAA_HUMAN	58	SSKA.\|.AMGI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)