P46776: 60S ribosomal protein L27a

General Information

Protein names	- 60S ribosomal protein L27a - Large ribosomal subunit protein uL15 {ECO:0000303\|PubMed:24524803}
Gene names	RPL27A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P46776

9 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGLHH HRINFDKYHP GYFGKVGMKH
        70         80         90        100        110        120
YHLKRNQSFC PTVNLDKLWT LVSEQTRVNA AKNKTGAAPI IDVVRSGYYK VLGKGKLPKQ
       130        140
PVIVKAKFFS RRAEEKIKSV GGACVLVA

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P46776-2-unknown	PSRLRK...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P46776-2-unknown	PSRLRK...	2	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P46776-43-	INFDKY...	43		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46776-58-unknown	MKHYHL...	58	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000431849
P46776-58-unknown	MKHYHL...	58	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000432671
P46776-58-unknown	MKHYHL...	58	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000431565
P46776-58-unknown	MKHYHL...	58	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000433766
P46776-79-unknown	WTLVSE...	79		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P46776-79-	WTLVSE...	79		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46776-79-	WTLVSE...	79		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P46776-93-	NKTGAA...	93		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P46776-93-	NKTGAA...	93		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46776-93-unknown	NKTGAA...	93		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P46776-95-unknown	TGAAPI...	95	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10088
P46776-97-unknown	AAPIID...	97	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7474

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...INFDKY	47	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437118
...AAKNKT	94	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10088
...KNKTGA	96	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7474
...CVLVA	148	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	94	KNKT.\|.TGAA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CATS_HUMAN	96	KTGA.\|.AAPI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)