Q9H0G5: Nuclear speckle splicing regulatory protein 1

General Information

Protein names	- Nuclear speckle splicing regulatory protein 1 - Coiled-coil domain-containing protein 55 - Nuclear speckle-related protein 70 - NSrp70
Gene names	NSRP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H0G5

3 N-termini

6 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAIPGRQYGL ILPKKTQQLH PVLQKPSVFG NDSDDDDETS VSESLQREAA KKQAMKQTKL
        70         80         90        100        110        120
EIQKALAEDA TVYEYDSIYD EMQKKKEENN PKLLLGKDRK PKYIHNLLKA VEIRKKEQEK
       130        140        150        160        170        180
RMEKKIQRER EMEKGEFDDK EAFVTSAYKK KLQERAEEEE REKRAAALEA CLDVTKQKDL
       190        200        210        220        230        240
SGFYRHLLNQ AVGEEEVPKC SFREARSGIK EEKSRGFSNE VSSKNRIPQE KCILQTDVKV
       250        260        270        280        290        300
EENPDADSDF DAKSSADDEI EETRVNCRRE KVIETPENDF KHHRSQNHSR SPSEERGHST
       310        320        330        340        350        360
RHHTKGSRTS RGHEKREDQH QQKQSRDQEN HYTDRDYRKE RDSHRHREAS HRDSHWKRHE
       370        380        390        400        410        420
QEDKPRARDQ RERSDRVWKR EKDREKYSQR EQERDRQQND QNRPSEKGEK EEKSKAKEEH
       430        440        450        460        470        480
MKVRKERYEN NDKYRDREKR EVGVQSSERN QDRKESSPNS RAKDKFLDQE RSNKMRNMAK
       490        500        510        520        530        540
DKERNQEKPS NSESSLGAKH RLTEEGQEKG KEQERPPEAV SKFAKRNNEE TVMSARDRYL
       550
ARQMARVNAK TYIEKEDD

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 6 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9H0G5-1-unknown	MAIPGR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9H0G5-55-unknown	MKQTKL...	55	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465442
Q9H0G5-55-unknown	MKQTKL...	55	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468327
Q9H0G5-55-unknown	MKQTKL...	55	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466463
Q9H0G5-207-unknown	SGIKEE...	207	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10545

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...RKKEQE	118	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000465442
...ERAEEE	158	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000466463
...FREARS	206	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10545
...SGIKEE	211	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000468327
...EKEDD	558	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EKEDD	558		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...EKEDD	558		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	206	EARS.\|.SGIK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)