Q02539: Histone H1.1

General Information

Protein names	- Histone H1.1 - Histone H1a
Gene names	HIST1H1A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q02539

6 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSETVPPAPA ASAAPEKPLA GKKAKKPAKA AAASKKKPAG PSVSELIVQA ASSSKERGGV
        70         80         90        100        110        120
SLAALKKALA AAGYDVEKNN SRIKLGIKSL VSKGTLVQTK GTGASGSFKL NKKASSVETK
       130        140        150        160        170        180
PGASKVATKT KATGASKKLK KATGASKKSV KTPKKAKKPA ATRKSSKNPK KPKTVKPKKV
       190        200        210
AKSPAKAKAV KPKAAKARVT KPKTAKPKKA APKKK

Isoforms

Sequence View

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Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q02539-2-unknown	MSETVP...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q02539-2-unknown	MSETVP...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q02539-2-Acetylation	SETVPP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q02539-2-Acetylation	SETVPP...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q02539-71-unknown	AAGYDV...	71		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14361
Q02539-71-unknown	AAGYDV...	71		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10189
Q02539-72-unknown	AGYDVE...	72		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14362
Q02539-74-unknown	YDVEKN...	74		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14363
Q02539-89-unknown	SLVSKG...	89		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14364

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KKALAA	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14361
...KKALAA	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10189
...KALAAA	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14362
...LAAAGY	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14363
...KLGIKS	88	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14364
...APKKK	215	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	70	ALAA.\|.AAGY	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAA_HUMAN	70	ALAA.\|.AAGY	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	71	LAAA.\|.AGYD	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	73	AAGY.\|.YDVE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	88	GIKS.\|.SLVS	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)