P18124: 60S ribosomal protein L7

General Information

Protein names	- 60S ribosomal protein L7 - Large ribosomal subunit protein uL30 {ECO:0000303\|PubMed:24524803}
Gene names	RPL7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P18124

8 N-termini

6 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEGVEEKKKE VPAVPETLKK KRRNFAELKI KRLRKKFAQK MLRKARRKLI YEKAKHYHKE
        70         80         90        100        110        120
YRQMYRTEIR MARMARKAGN FYVPAEPKLA FVIRIRGING VSPKVRKVLQ LLRLRQIFNG
       130        140        150        160        170        180
TFVKLNKASI NMLRIVEPYI AWGYPNLKSV NELIYKRGYG KINKKRIALT DNALIARSLG
       190        200        210        220        230        240
KYGIICMEDL IHEIYTVGKR FKEANNFLWP FKLSSPRGGM KKKTTHFVEG GDAGNREDQI

NRLIRRMN

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

8 N-termini - 6 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P18124-1-Acetylation	MEGVEE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P18124-1-Acetylation	MEGVEE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P18124-1-Acetylation	MEGVEE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P18124-8-unknown	KKEVPA...	8			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P18124-12-unknown	PAVPET...	12		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P18124-17-unknown	TLKKKR...	17		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11273
P18124-41-unknown	MLRKAR...	41		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000379731
P18124-41-unknown	MLRKAR...	41		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000379730
P18124-41-unknown	MLRKAR...	41		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000379729
P18124-41-unknown	MLRKAR...	41		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000415808
P18124-41-unknown	MLRKAR...	41		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000401300
P18124-78-unknown	AGNFYV...	78		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10003
P18124-78-	AGNFYV...	78			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P18124-78-	AGNFYV...	78			Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P18124-230-unknown	GGDAGN...	230		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5635
P18124-230-unknown	GGDAGN...	230		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7354

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PAVPET	16	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11273
...RMARKA	77	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10003
...KLNKAS	128	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401300
...IVEPYI	139	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415808
...THFVEG	229	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5635
...THFVEG	229	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7354
...IRRMN	248	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	16	VPET.\|.TLKK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAA_HUMAN	77	ARKA.\|.AGNF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CATL1_HUMAN	229	FVEG.\|.GGDA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	229	FVEG.\|.GGDA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)