Q13573: SNW domain-containing protein 1

General Information

Protein names	- SNW domain-containing protein 1 - Nuclear protein SkiP - Nuclear receptor coactivator NCoA-62 {ECO:0000303\|PubMed:9632709} - Ski-interacting protein {ECO:0000303\|PubMed:11278756, ECO:0000303\|PubMed:9569025}
Gene names	SNW1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13573

11 N-termini

6 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALTSFLPAP TQLSQDQLEA EEKARSQRSR QTSLVSSRRE PPPYGYRKGW IPRLLEDFGD
        70         80         90        100        110        120
GGAFPEIHVA QYPLDMGRKK KMSNALAIQV DSEGKIKYDA IARQGQSKDK VIYSKYTDLV
       130        140        150        160        170        180
PKEVMNADDP DLQRPDEEAI KEITEKTRVA LEKSVSQKVA AAMPVRAADK LAPAQYIRYT
       190        200        210        220        230        240
PSQQGVAFNS GAKQRVIRMV EMQKDPMEPP RFKINKKIPR GPPSPPAPVM HSPSRKMTVK
       250        260        270        280        290        300
EQQEWKIPPC ISNWKNAKGY TIPLDKRLAA DGRGLQTVHI NENFAKLAEA LYIADRKARE
       310        320        330        340        350        360
AVEMRAQVER KMAQKEKEKH EEKLREMAQK ARERRAGIKT HVEKEDGEAR ERDEIRHDRR
       370        380        390        400        410        420
KERQHDRNLS RAAPDKRSKL QRNENRDISE VIALGVPNPR TSNEVQYDQR LFNQSKGMDS
       430        440        450        460        470        480
GFAGGEDEIY NVYDQAWRGG KDMAQSIYRP SKNLDKDMYG DDLEARIKTN RFVPDKEFSG
       490        500        510        520        530
SDRRQRGREG PVQFEEDPFG LDKFLEEAKQ HGGSKRPSDS SRPKEHEHEG KKRRKE

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

11 N-termini - 6 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13573-2-unknown	MALTSF...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13573-2-Acetylation	ALTSFL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13573-2-Acetylation	ALTSFL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q13573-2-Acetylation	ALTSFL...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q13573-2-Acetylation	ALTSFL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q13573-5-	SFLPAP...	5			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q13573-17-unknown	QLEAEE...	17		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12097
Q13573-92-unknown	SEGKIK...	92		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12098
Q13573-161-	AAMPVR...	161			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q13573-163-unknown	MPVRAA...	163		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000452059
Q13573-200-unknown	VEMQKD...	200			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q13573-200-	VEMQKD...	200			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q13573-277-unknown	TVHINE...	277		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6351
Q13573-401-unknown	TSNEVQ...	401		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10267

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QLSQDQ	16	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12097
...AIQVDS	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12098
...GRGLQT	276	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6351
...LQTVHI	279	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452473
...VPNPRT	400	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10267
...KRRKE	536	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	16	SQDQ.\|.QLEA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	91	QVDS.\|.SEGK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CATL1_HUMAN	276	GLQT.\|.TVHI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAA_HUMAN	400	NPRT.\|.TSNE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)