P0CG39: POTE ankyrin domain family member J

General Information

Protein names	- POTE ankyrin domain family member J
Gene names	POTEJ
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P0CG39

14 N-termini

14 C-termini

14 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVAEVDSMPA ASSVKKPFVL RSKMGKWCRH CFPCCRGSGK SNVGTSGDQD DSTMKTLRSK
        70         80         90        100        110        120
MGKWCCHCFP CCRGSGKSNV GAWGDYDDSA FVEPRYHVRR EDLDKLHRAA WWGKVARKDL
       130        140        150        160        170        180
IVMLRDTDVN KQDKQKRTAL HLASANGNSG VVKLLLDRRC QLNVLDNKKR TALTKAVQCQ
       190        200        210        220        230        240
EDECALMLLE HGTDPNIPDE YGNTTLHYAI YNEDKLMAKA LLLYGADIES KNKHGLTPLL
       250        260        270        280        290        300
LGVHEQKQQV VKFLIKKKAN LNALDRYGRT ALILAVCCGS ASIVSLLLEQ NIDVSSQDLS
       310        320        330        340        350        360
GQTAREYAVS SHHHVICQLL SDYKEKQMLK ISSENSNPEQ DLKLTSEEES QRFKGSENSQ
       370        380        390        400        410        420
PEKMSQEPEI NKDGDREVEE EMKKHESNNV GLLENLSNGV TAGNGDDGLI PQRKSRTPEN
       430        440        450        460        470        480
QQFPDNESEE YHRICELVSD YKEKQMPKYS SENSNPEQDL KLTSEEESQR LKGSENGQPE
       490        500        510        520        530        540
KRSQEPEINK DGDRELENFM AIEEMKKHGS THVGFPENLT NGATAGNGDD GLIPPRKSRT
       550        560        570        580        590        600
PESQQFPDTE NEEYHSDEQN DTQKQFCEEQ NTGILHDEIL IHEEKQIEVV EKMNSELSLS
       610        620        630        640        650        660
CKKERDFLHE NSMLREEIAM LRLELDTMKH QSQLRKKKYL EDIESVKKKN DNLLKALQLN
       670        680        690        700        710        720
ELTMDDDTAV LVIDNGSGMC KAGFAGDDAP RAVFPSIVGC PRQQGMMGGM HQKESYVGKE
       730        740        750        760        770        780
AQSKRGILTL KYPMEHGIIT NWDDMEKIWH HTFYNELRVA PEEHPILLTE APLNPKANRE
       790        800        810        820        830        840
KMTQIMFETF NTPAMYVAIQ AMLSLYTSGR TTGIVMDSGD GVTHTVPIYD GNALPHATLR
       850        860        870        880        890        900
LDLAGRELTD YLMKILTERG YRFTTMAERE IVRDIKEKLC YVALDFEQEM AMVASSSSLE
       910        920        930        940        950        960
KSYELPDGQV ITISNEWFRC PEALFQPCFL GMESCGIHET TFNSIMKSDV DIRKDLYTNT
       970        980        990       1000       1010       1020
VLSGGTTMYP GMAHRMQKEI AALAPSMMKI RIIAPPKRKY SVWVGGSILA SLSTFQQMWI
      1030
SKQEYDESGP SIVHRKCF

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

14 N-termini - 14 C-termini - 14 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P0CG39-1-unknown	MVAEVD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P0CG39-672-unknown	VIDNGS...	672	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13954
P0CG39-675-unknown	NGSGMC...	675	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1625
P0CG39-681-unknown	KAGFAG...	681	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15323
P0CG39-682-unknown	AGFAGD...	682	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9970
P0CG39-743-unknown	DDMEKI...	743	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18638
P0CG39-745-unknown	MEKIWH...	745	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18639
P0CG39-750-unknown	HHTFYN...	750	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18640
P0CG39-769-unknown	TEAPLN...	769	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18641
P0CG39-769-unknown	TEAPLN...	769	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15324
P0CG39-770-unknown	EAPLNP...	770	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15325
P0CG39-880-unknown	CYVALD...	880	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13955
P0CG39-937-unknown	IHETTF...	937	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18642
P0CG39-1018-unknown	MWISKQ...	1018	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18643
P0CG39-1026-unknown	DESGPS...	1026	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18644

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DTAVLV	671	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13954
...VLVIDN	674	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1625
...GSGMCK	680	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15323
...SGMCKA	681	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9970
...IITNWD	742	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18638
...TNWDDM	744	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18639
...MEKIWH	749	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18640
...HPILLT	768	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18641
...HPILLT	768	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15324
...PILLTE	769	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15325
...IKEKLC	879	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13955
...MESCGI	936	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18642
...STFQQM	1017	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18643
...SKQEYD	1025	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18644
...HRKCF	1038	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	671	AVLV.\|.VIDN	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CASP3_HUMAN	674	VIDN.\|.NGSG	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
HTRA2_HUMAN	680	GMCK.\|.KAGF	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAA_HUMAN	681	MCKA.\|.AGFA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
MEP1B_HUMAN	742	TNWD.\|.DDME	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	744	WDDM.\|.MEKI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	749	KIWH.\|.HHTF	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	768	ILLT.\|.TEAP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
HTRA2_HUMAN	768	ILLT.\|.TEAP	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
HTRA2_HUMAN	769	LLTE.\|.EAPL	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAM_HUMAN	879	EKLC.\|.CYVA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
MEP1B_HUMAN	936	SCGI.\|.IHET	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	1017	FQQM.\|.MWIS	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	1025	QEYD.\|.DESG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)