Q86X53: Glutamate-rich protein 1

General Information

Protein names	- Glutamate-rich protein 1
Gene names	ERICH1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86X53

5 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAHRKHVFV EKVLQRLFPP VPSGQGKREP QTLAVQNPPK KVTSEKVSQK HAEPLTDTGS
        70         80         90        100        110        120
ETPTARRLYT ASGPPEGYVP CWPEPSSCGS PENASSGDDT EDQDPHDQPK RRRIRKHKSK
       130        140        150        160        170        180
KKFKNPNNVL IEQAELEKQQ SLLQEKSQRQ HTDGTTISKN KKRKLKKKQQ IKRKKAAGLA
       190        200        210        220        230        240
AKAAGVSFMY QPEDSSNEGE GVGEACEEDG VDTSEEDPTL AGEEDVKDTR EEDGADASEE
       250        260        270        280        290        300
DLTRARQEEG ADASEEDPTP AGEEDVKDAR EEDGVDTIEE DLTRAGEEDG KDTREEDGAD
       310        320        330        340        350        360
ASEEDPTWAG EEEGADSGEE DGADASEEDD TITNEKAHSI LNFLKSTQEM YFYDGVSRDA
       370        380        390        400        410        420
ASAALADAAE ELLDRLASHS MLPSDVSILY HMKTLLLLQD TERLKHALEM FPEHCTMPPD
       430        440
HARVISAFFS YWITHILPEK SSD

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q86X53-1-unknown	MAAHRK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q86X53-56-unknown	TDTGSE...	56		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q86X53-56-	TDTGSE...	56		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q86X53-247-unknown	QEEGAD...	247	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10407
Q86X53-277-	TIEEDL...	277		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...LTRARQ	246	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10407
	...EKSSD	443	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	246	RARQ.\|.QEEG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)