Q9BU76: Multiple myeloma tumor-associated protein 2

General Information

Protein names	- Multiple myeloma tumor-associated protein 2 - hMMTAG2
Gene names	MMTAG2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BU76

4 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Multiple myeloma tumor-associated protein 2 - Isoform 3 of Multiple myeloma tumor-associated protein 2 - Isoform 4 of Multiple myeloma tumor-associated protein 2

Sequence View

        10         20         30         40         50         60
MFGSSRGGVR GGQDQFNWED VKTDKQRENY LGNSLMAPVG RWQKGRDLTW YAKGRAPCAG
        70         80         90        100        110        120
PSREEELAAV REAEREALLA ALGYKNVKKQ PTGLSKEDFA EVCKREGGDP EEKGVDRLLG
       130        140        150        160        170        180
LGSASGSVGR VAMSREDKEA AKLGLSVFTH HRVESGGPGT SAASARRKPR AEDQTESSCE
       190        200        210        220        230        240
SHRKSKKEKK KKKKRKHKKE KKKKDKEHRR PAEATSSPTS PERPRHHHHD SDSNSPCCKR
       250        260
RKRGHSGDRR SPSRRWHDRG SEA         10         20         30         40         50         60
MFGSSRGGVR GGQDQFNWED VKTDKQRENY LGNSLMAPVG RWQKGRDLTW YAKGRAPCAG
        70         80         90        100        110        120
PSREEELAAV REAEREALLA ALGYKNVKKQ PTGLSKEDFA EVCKREGGDP EEKGVDRLLG
       130        140        150        160        170        180
LGSASGSVGR VAMSREDKEA AKLGLSVFTH HRVESGGPGT SAASARRKPR AEDQTESSCE
       190        200        210        220        230        240
SHRKSKKEKK KKKKRKHKKE KKKKDKEHRR PAEATSSPTS PERPRHHHHD SDSNSPCCKR
       250        260
RKRGHSGDRR SPSRRWHDRG SEA         10         20         30         40         50         60
MFGSSRGGVR GGQDQFNWED VKTDKQRENY LGNSLMAPVG RWQKGRDLTW YAKGRAPCAG
        70         80         90        100        110        120
PSREEELAAV REAEREALLA ALGYKNVKKQ PTGLSKEDFA EVCKREGGDP EEKGVDRLLG
       130        140        150        160        170        180
LGSASGSVGR VAMSREDKEA AKLGLSVFTH HRVESGGPGT SAASARRKPR AEDQTESSCE
       190        200        210        220        230        240
SHRKSKKEKK KKKKRKHKKE KKKKDKEHRR PAEATSSPTS PERPRHHHHD SDSNSPCCKR
       250        260
RKRGHSGDRR SPSRRWHDRG SEA

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9BU76-1-unknown	MFGSSR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BU76-1-unknown	MFGSSR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81309
Q9BU76-1-unknown	MFGSSR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81310
Q9BU76-1-unknown	MFGSSR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81311
Q9BU76-106-unknown	EGGDPE...	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10523
Q9BU76-106-unknown	EGGDPE...	106	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142669
Q9BU76-106-unknown	EGGDPE...	106	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142670
Q9BU76-146-unknown	SVFTHH...	146	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14950
Q9BU76-146-unknown	SVFTHH...	146	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144563
Q9BU76-171-unknown	AEDQTE...	171	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10527

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EVCKRE	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10523
...EVCKRE	105	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125869
...EVCKRE	105	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125870
...EVCKRE	105	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125871
...AKLGLS	145	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14950
...AKLGLS	145	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127830
...AKLGLS	145	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154903
...RRKPRA	170	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10527
...RRKPRA	170	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155265
...RGSEA	263	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	105	CKRE.\|.EGGD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	145	LGLS.\|.SVFT	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAA_HUMAN	170	KPRA.\|.AEDQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)