P22626: Heterogeneous nuclear ribonucleoproteins A2/B1

General Information

Protein names	- Heterogeneous nuclear ribonucleoproteins A2/B1 - hnRNP A2/B1
Gene names	HNRNPA2B1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P22626

81 N-termini

25 C-termini

35 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEKTLETVPL ERKKREKEQF RKLFIGGLSF ETTEESLRNY YEQWGKLTDC VVMRDPASKR
        70         80         90        100        110        120
SRGFGFVTFS SMAEVDAAMA ARPHSIDGRV VEPKRAVARE ESGKPGAHVT VKKLFVGGIK
       130        140        150        160        170        180
EDTEEHHLRD YFEEYGKIDT IEIITDRQSG KKRGFGFVTF DDHDPVDKIV LQKYHTINGH
       190        200        210        220        230        240
NAEVRKALSR QEMQEVQSSR SGRGGNFGFG DSRGGGGNFG PGPGSNFRGG SDGYGSGRGF
       250        260        270        280        290        300
GDGYNGYGGG PGGGNFGGSP GYGGGRGGYG GGGPGYGNQG GGYGGGYDNY GGGNYGSGNY
       310        320        330        340        350
NDFGNYNQQP SNYGPMKSGN FGGSRNMGGP YGGGNYGPGG SGGSGGYGGR SRY

Isoforms

- Isoform A2 of Heterogeneous nuclear ribonucleoproteins A2/B1

Sequence View

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Protein Neighborhood

Domains & Features

81 N-termini - 25 C-termini - 35 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P22626-1-Acetylation	MEKTLE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P22626-1-Acetylation	MEKTLE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P22626-1-Acetylation	MEKTLE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P22626-1-Acetylation	MEKTLE...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P22626-4-	TLETVP...	4			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-24-	FIGGLS...	24			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P22626-24-unknown	FIGGLS...	24		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176473
P22626-29-	SFETTE...	29			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-29-unknown	SFETTE...	29		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14036
P22626-29-unknown	SFETTE...	29		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136662
P22626-41-unknown	YEQWGK...	41		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17493
P22626-41-unknown	YEQWGK...	41		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18909
P22626-41-unknown	YEQWGK...	41		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137461
P22626-50-unknown	CVVMRD...	50		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1733
P22626-50-unknown	CVVMRD...	50		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138198
P22626-56-unknown	PASKRS...	56		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1735
P22626-56-unknown	PASKRS...	56		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138683
P22626-69-unknown	FSSMAE...	69		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3705
P22626-69-unknown	FSSMAE...	69		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139676
P22626-70-	SSMAEV...	70			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-70-	SSMAEV...	70			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P22626-70-	SSMAEV...	70			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P22626-70-unknown	SSMAEV...	70		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170254
P22626-71-	SMAEVD...	71			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P22626-71-	SMAEVD...	71			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-71-unknown	SMAEVD...	71		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166274
P22626-72-	MAEVDA...	72			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-72-unknown	MAEVDA...	72		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172937
P22626-75-unknown	VDAAMA...	75		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3707
P22626-75-unknown	VDAAMA...	75		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt140180
P22626-77-	AAMAAR...	77			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P22626-77-	AAMAAR...	77			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P22626-77-	AAMAAR...	77			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P22626-77-	AAMAAR...	77			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P22626-77-	AAMAAR...	77			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-77-	AAMAAR...	77			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P22626-77-unknown	AAMAAR...	77			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P22626-77-unknown	AAMAAR...	77			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P22626-77-unknown	AAMAAR...	77		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160176
P22626-78-	AMAARP...	78			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-78-unknown	AMAARP...	78		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170256
P22626-80-	AARPHS...	80			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P22626-80-	AARPHS...	80			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-80-	AARPHS...	80			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P22626-80-unknown	AARPHS...	80			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P22626-80-unknown	AARPHS...	80		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162025
P22626-96-unknown	AVAREE...	96		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166277
P22626-96-	AVAREE...	96			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P22626-96-	AVAREE...	96			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-96-	AVAREE...	96			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P22626-100-unknown	EESGKP...	100		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165855
P22626-100-	EESGKP...	100			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P22626-114-	LFVGGI...	114			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P22626-114-	LFVGGI...	114			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P22626-114-unknown	LFVGGI...	114		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176475
P22626-115-unknown	FVGGIK...	115		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176635
P22626-115-	FVGGIK...	115			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P22626-115-	FVGGIK...	115			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P22626-116-unknown	VGGIKE...	116		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17495
P22626-116-unknown	VGGIKE...	116		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18911
P22626-116-unknown	VGGIKE...	116		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142588
P22626-118-unknown	GIKEDT...	118		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17497
P22626-118-unknown	GIKEDT...	118		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18913
P22626-118-unknown	GIKEDT...	118		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142688
P22626-118-	GIKEDT...	118			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-118-	GIKEDT...	118			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P22626-131-unknown	YFEEYG...	131		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175050
P22626-131-	YFEEYG...	131			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P22626-131-	YFEEYG...	131			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P22626-132-unknown	FEEYGK...	132		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17499
P22626-132-unknown	FEEYGK...	132		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18915
P22626-132-unknown	FEEYGK...	132		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143471
P22626-133-unknown	EEYGKI...	133		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18917
P22626-133-unknown	EEYGKI...	133		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143548
P22626-134-unknown	EYGKID...	134		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17501
P22626-134-unknown	EYGKID...	134		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18919
P22626-134-unknown	EYGKID...	134		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143562
P22626-135-unknown	YGKIDT...	135		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17503
P22626-135-unknown	YGKIDT...	135		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18921
P22626-135-unknown	YGKIDT...	135		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143603
P22626-136-	GKIDTI...	136			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-136-	GKIDTI...	136			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P22626-136-unknown	GKIDTI...	136		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172940
P22626-154-	GFGFVT...	154			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P22626-154-	GFGFVT...	154			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-154-	GFGFVT...	154			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P22626-154-	GFGFVT...	154			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P22626-154-	GFGFVT...	154			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P22626-154-	GFGFVT...	154			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P22626-154-	GFGFVT...	154			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P22626-154-unknown	GFGFVT...	154		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166270
P22626-157-unknown	FVTFDD...	157		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5698
P22626-157-unknown	FVTFDD...	157		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3709
P22626-157-unknown	FVTFDD...	157		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7374
P22626-157-unknown	FVTFDD...	157		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144521
P22626-159-unknown	TFDDHD...	159		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5700
P22626-159-unknown	TFDDHD...	159		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144591
P22626-160-unknown	FDDHDP...	160		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3711
P22626-160-unknown	FDDHDP...	160		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144639
P22626-164-unknown	DPVDKI...	164		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17505
P22626-164-unknown	DPVDKI...	164		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18923
P22626-164-unknown	DPVDKI...	164		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144817
P22626-176-unknown	TINGHN...	176		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5702
P22626-176-unknown	TINGHN...	176		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145297
P22626-176-	TINGHN...	176			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P22626-193-unknown	MQEVQS...	193		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166279
P22626-193-	MQEVQS...	193			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P22626-193-	MQEVQS...	193			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-204-unknown	GGNFGF...	204		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175048
P22626-204-	GGNFGF...	204			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P22626-205-unknown	GNFGFG...	205		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3713
P22626-205-unknown	GNFGFG...	205		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146360
P22626-209-unknown	FGDSRG...	209		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3715
P22626-209-unknown	FGDSRG...	209		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146494
P22626-211-unknown	DSRGGG...	211		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5704
P22626-211-unknown	DSRGGG...	211		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146544
P22626-214-unknown	GGGGNF...	214		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10033
P22626-214-unknown	GGGGNF...	214		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146624
P22626-219-unknown	FGPGPG...	219		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17507
P22626-219-unknown	FGPGPG...	219		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146794
P22626-229-unknown	GGSDGY...	229			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P22626-229-unknown	GGSDGY...	229		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160178
P22626-246-	GYGGGP...	246			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P22626-246-	GYGGGP...	246			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-246-	GYGGGP...	246			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P22626-246-	GYGGGP...	246			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P22626-246-unknown	GYGGGP...	246		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166268
P22626-248-	GGGPGG...	248			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-248-unknown	GGGPGG...	248		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172931
P22626-291-unknown	GGGNYG...	291		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172933
P22626-291-	GGGNYG...	291			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-291-	GGGNYG...	291			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P22626-291-	GGGNYG...	291			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P22626-302-unknown	DFGNYN...	302		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166272
P22626-302-	DFGNYN...	302			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P22626-304-unknown	GNYNQQ...	304		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172935
P22626-304-	GNYNQQ...	304			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P22626-304-	GNYNQQ...	304			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P22626-305-unknown	NYNQQP...	305		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166281
P22626-305-	NYNQQP...	305			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P22626-312-unknown	NYGPMK...	312		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14038
P22626-312-unknown	NYGPMK...	312		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149875
P22626-317-	KSGNFG...	317			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P22626-317-unknown	KSGNFG...	317		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164803
P22626-318-	SGNFGG...	318			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P22626-318-	SGNFGG...	318			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P22626-318-unknown	SGNFGG...	318			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P22626-318-unknown	SGNFGG...	318		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162027
P22626-326-unknown	NMGGPY...	326		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174523
P22626-326-	NMGGPY...	326			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P22626-326-	NMGGPY...	326			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P22626-326-	NMGGPY...	326			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P22626-326-	NMGGPY...	326			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P22626-333-unknown	GGNYGP...	333		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5706
P22626-333-unknown	GGNYGP...	333		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3717
P22626-333-unknown	GGNYGP...	333		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7376
P22626-333-unknown	GGNYGP...	333		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150353
P22626-333-	GGNYGP...	333			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FIGGLS	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14036
...SLRNYY	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17493
...SLRNYY	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18909
...SLRNYY	40	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120427
...GKLTDC	49	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1733
...GKLTDC	49	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121227
...VVMRDP	55	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1735
...VVMRDP	55	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121737
...FGFVTF	68	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3705
...FGFVTF	68	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122775
...SSMAEV	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3707
...SSMAEV	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123293
...VKKLFV	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17495
...VKKLFV	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18911
...VKKLFV	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125782
...KLFVGG	117	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17497
...KLFVGG	117	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18913
...KLFVGG	117	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125888
...HLRDYF	131	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17499
...HLRDYF	131	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18915
...HLRDYF	131	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126704
...LRDYFE	132	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18917
...LRDYFE	132	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126788
...RDYFEE	133	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17501
...RDYFEE	133	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18919
...RDYFEE	133	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126803
...DYFEEY	134	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17503
...DYFEEY	134	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18921
...DYFEEY	134	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126845
...KRGFGF	156	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5698
...KRGFGF	156	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3709
...KRGFGF	156	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7374
...KRGFGF	156	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127788
...GFGFVT	158	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5700
...GFGFVT	158	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127858
...FGFVTF	159	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3711
...FGFVTF	159	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127906
...TFDDHD	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17505
...TFDDHD	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18923
...TFDDHD	163	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128093
...LQKYHT	175	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5702
...LQKYHT	175	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128588
...RSGRGG	204	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3713
...RSGRGG	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129664
...GGNFGF	208	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3715
...GGNFGF	208	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129802
...NFGFGD	210	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5704
...NFGFGD	210	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129851
...FGDSRG	213	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10033
...FGDSRG	213	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129931
...GGGGNF	218	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17507
...GGGGNF	218	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130116
...NQQPSN	311	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14038
...NQQPSN	311	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133266
...GGPYGG	332	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5706
...GGPYGG	332	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3717
...GGPYGG	332	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7376
...GGPYGG	332	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133750
...GRSRY	353	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GRSRY	353	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83669

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	28	GGLS.\|.SFET	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
MEP1A_HUMAN	40	RNYY.\|.YEQW	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	40	RNYY.\|.YEQW	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CASP3_HUMAN	49	LTDC.\|.CVVM	inferred from experiment	unknown	MEROPS	Rudel T	Thiede B et al.:Predominant identification of R... (C14.003)	11352910,
CASP3_HUMAN	55	MRDP.\|.PASK	inferred from experiment	unknown	MEROPS	Rudel T	Thiede B et al.:Predominant identification of R... (C14.003)	11352910,
CATB_HUMAN	68	FVTF.\|.FSSM	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	74	MAEV.\|.VDAA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	115	KLFV.\|.VGGI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	115	KLFV.\|.VGGI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	117	FVGG.\|.GIKE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	117	FVGG.\|.GIKE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	131	RDYF.\|.FEEY	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	131	RDYF.\|.FEEY	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	132	DYFE.\|.EEYG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	133	YFEE.\|.EYGK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	133	YFEE.\|.EYGK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	134	FEEY.\|.YGKI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	134	FEEY.\|.YGKI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	156	GFGF.\|.FVTF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	156	GFGF.\|.FVTF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	156	GFGF.\|.FVTF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	158	GFVT.\|.TFDD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	159	FVTF.\|.FDDH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	163	DDHD.\|.DPVD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	163	DDHD.\|.DPVD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	175	KYHT.\|.TING	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	204	GRGG.\|.GNFG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	208	NFGF.\|.FGDS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	210	GFGD.\|.DSRG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAA_HUMAN	213	DSRG.\|.GGGG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
MEP1A_HUMAN	218	GGNF.\|.FGPG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAM_HUMAN	311	QPSN.\|.NYGP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATL1_HUMAN	332	PYGG.\|.GGNY	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	332	PYGG.\|.GGNY	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	332	PYGG.\|.GGNY	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)