Q9P258: Protein RCC2

General Information

Protein names	- Protein RCC2 - RCC1-like protein TD-60 {ECO:0000303\|PubMed:12919680} - Telophase disk protein of 60 kDa {ECO:0000303\|PubMed:1939370}
Gene names	RCC2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9P258

9 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPRKKAAAAA WEEPSSGNGT ARAGPRKRGG PAGRKRERPE RCSSSSGGGS SGDEDGLELD
        70         80         90        100        110        120
GAPGGGKRAA RPATAGKAGG AAVVITEPEH TKERVKLEGS KCKGQLLIFG ATNWDLIGRK
       130        140        150        160        170        180
EVPKQQAAYR NLGQNLWGPH RYGCLAGVRV RTVVSGSCAA HSLLITTEGK LWSWGRNEKG
       190        200        210        220        230        240
QLGHGDTKRV EAPRLIEGLS HEVIVSAACG RNHTLALTET GSVFAFGENK MGQLGLGNQT
       250        260        270        280        290        300
DAVPSPAQIM YNGQPITKMA CGAEFSMIMD CKGNLYSFGC PEYGQLGHNS DGKFIARAQR
       310        320        330        340        350        360
IEYDCELVPR RVAIFIEKTK DGQILPVPNV VVRDVACGAN HTLVLDSQKR VFSWGFGGYG
       370        380        390        400        410        420
RLGHAEQKDE MVPRLVKLFD FPGRGASQIY AGYTCSFAVS EVGGLFFWGA TNTSRESTMY
       430        440        450        460        470        480
PKAVQDLCGW RIRSLACGKS SIIVAADEST ISWGPSPTFG ELGYGDHKPK SSTAAQEVKT
       490        500        510        520
LDGIFSEQVA MGYSHSLVIA RDESETEKEK IKKLPEYNPR TL

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

9 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9P258-1-unknown	MPRKKA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9P258-72-	PATAGK...	72		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9P258-74-unknown	TAGKAG...	74	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19829
Q9P258-74-unknown	TAGKAG...	74	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18156
Q9P258-78-unknown	AGGAAV...	78	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10578
Q9P258-80-	GAAVVI...	80		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9P258-82-unknown	AVVITE...	82	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18157
Q9P258-202-unknown	EVIVSA...	202	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19830
Q9P258-242-	AVPSPA...	242		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9P258-471-	SSTAAQ...	471		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AARPAT	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19829
...AARPAT	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18156
...ATAGKA	77	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10578
...KAGGAA	81	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18157
...EGLSHE	201	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19830
...NPRTL	522	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	73	RPAT.\|.TAGK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	73	RPAT.\|.TAGK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAA_HUMAN	77	AGKA.\|.AGGA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
MEP1A_HUMAN	81	GGAA.\|.AVVI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	201	LSHE.\|.EVIV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)