P50914: 60S ribosomal protein L14

General Information

Protein names	- 60S ribosomal protein L14 - CAG-ISL 7 - Large ribosomal subunit protein eL14 {ECO:0000303\|PubMed:24524803}
Gene names	RPL14
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P50914

14 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTQVRRQAM PFKCMQLTDF
        70         80         90        100        110        120
ILKFPHSAHQ KYVRQAWQKA DINTKWAATR WAKKIEARER KAKMTDFDRF KVMKAKKMRN
       130        140        150        160        170        180
RIIKNEVKKL QKAALLKASP KKAPGTKGTA AAAAAAAAAK VPAKKITAAS KKAPAQKVPA
       190        200        210
QKATGQKAAP APKAQKGQKA PAQKAPAPKA SGKKA

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

14 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P50914-2-unknown	VFRRFV...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P50914-4-unknown	RRFVEV...	4	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P50914-16-unknown	SFGPHA...	16	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5951
P50914-27-unknown	IVDVID...	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5952
P50914-27-unknown	IVDVID...	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7526
P50914-101-unknown	KAKMTD...	101	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10095
P50914-109-unknown	RFKVMK...	109	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11621
P50914-173-	APAQKV...	173		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P50914-178-	VPAQKA...	178		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P50914-178-	VPAQKA...	178		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P50914-178-	VPAQKA...	178		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P50914-178-	VPAQKA...	178		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P50914-181-unknown	QKATGQ...	181		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P50914-181-unknown	QKATGQ...	181		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P50914-183-	ATGQKA...	183		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P50914-183-	ATGQKA...	183		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P50914-183-	ATGQKA...	183		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P50914-183-	ATGQKA...	183		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P50914-183-	ATGQKA...	183		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P50914-183-	ATGQKA...	183		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P50914-197-	GQKAPA...	197		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P50914-198-unknown	QKAPAQ...	198		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P50914-200-	APAQKA...	200		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P50914-200-	APAQKA...	200		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P50914-200-	APAQKA...	200		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P50914-200-	APAQKA...	200		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P50914-200-	APAQKA...	200		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P50914-205-	APAPKA...	205		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RVAYVS	15	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5951
...GKLVAI	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5952
...GKLVAI	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7526
...EARERK	100	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10095
...MTDFDR	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11621
...SGKKA	215	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	15	AYVS.\|.SFGP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	26	LVAI.\|.IVDV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	26	LVAI.\|.IVDV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAA_HUMAN	100	RERK.\|.KAKM	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	108	DFDR.\|.RFKV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)