Q14498: RNA-binding protein 39

General Information

Protein names	- RNA-binding protein 39 - CAPER alpha - Hepatocellular carcinoma protein 1 - RNA-binding motif protein 39 - RNA-binding region-containing protein 2 - Splicing factor HCC1
Gene names	RBM39
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14498

21 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of RNA-binding protein 39 - Isoform 3 of RNA-binding protein 39

Sequence View

        10         20         30         40         50         60
MADDIDIEAM LEAPYKKDEN KLSSANGHEE RSKKRKKSKS RSRSHERKRS KSKERKRSRD
        70         80         90        100        110        120
RERKKSKSRE RKRSRSKERR RSRSRSRDRR FRGRYRSPYS GPKFNSAIRG KIGLPHSIKL
       130        140        150        160        170        180
SRRRSRSKSP FRKDKSPVRE PIDNLTPEER DARTVFCMQL AARIRPRDLE EFFSTVGKVR
       190        200        210        220        230        240
DVRMISDRNS RRSKGIAYVE FVDVSSVPLA IGLTGQRVLG VPIIVQASQA EKNRAAAMAN
       250        260        270        280        290        300
NLQKGSAGPM RLYVGSLHFN ITEDMLRGIF EPFGRIESIQ LMMDSETGRS KGYGFITFSD
       310        320        330        340        350        360
SECAKKALEQ LNGFELAGRP MKVGHVTERT DASSASSFLD SDELERTGID LGTTGRLQLM
       370        380        390        400        410        420
ARLAEGTGLQ IPPAAQQALQ MSGSLAFGAV AEFSFVIDLQ TRLSQQTEAS ALAAAASVQP
       430        440        450        460        470        480
LATQCFQLSN MFNPQTEEEV GWDTEIKDDV IEECNKHGGV IHIYVDKNSA QGNVYVKCPS
       490        500        510        520        530
IAAAIAAVNA LHGRWFAGKM ITAAYVPLPT YHNLFPDSMT ATQLLVPSRR         10         20         30         40         50         60
MADDIDIEAM LEAPYKKDEN KLSSANGHEE RSKKRKKSKS RSRSHERKRS KSKERKRSRD
        70         80         90        100        110        120
RERKKSKSRE RKRSRSKERR RSRSRSRDRR FRGRYRSPYS GPKFNSAIRG KIGLPHSIKL
       130        140        150        160        170        180
SRRRSRSKSP FRKDKSPVRE PIDNLTPEER DARTVFCMQL AARIRPRDLE EFFSTVGKVR
       190        200        210        220        230        240
DVRMISDRNS RRSKGIAYVE FVDVSSVPLA IGLTGQRVLG VPIIVQASQA EKNRAAAMAN
       250        260        270        280        290        300
NLQKGSAGPM RLYVGSLHFN ITEDMLRGIF EPFGRIESIQ LMMDSETGRS KGYGFITFSD
       310        320        330        340        350        360
SECAKKALEQ LNGFELAGRP MKVGHVTERT DASSASSFLD SDELERTGID LGTTGRLQLM
       370        380        390        400        410        420
ARLAEGTGLQ IPPAAQQALQ MSGSLAFGAV AEFSFVIDLQ TRLSQQTEAS ALAAAASVQP
       430        440        450        460        470        480
LATQCFQLSN MFNPQTEEEV GWDTEIKDDV IEECNKHGGV IHIYVDKNSA QGNVYVKCPS
       490        500        510        520        530
IAAAIAAVNA LHGRWFAGKM ITAAYVPLPT YHNLFPDSMT ATQLLVPSRR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

21 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q14498-2-unknown	MADDID...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14498-1-unknown	MADDID...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87122
Q14498-1-unknown	MADDID...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87123
Q14498-2-Acetylation	ADDIDI...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14498-2-Acetylation	ADDIDI...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q14498-2-Acetylation	ADDIDI...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110468
Q14498-2-Acetylation	ADDIDI...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110469
Q14498-218-unknown	VLGVPI...	218		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10288
Q14498-218-unknown	VLGVPI...	218		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146455
Q14498-218-unknown	VLGVPI...	218		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147260
Q14498-235-unknown	AAAMAN...	235		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176524
Q14498-235-unknown	AAAMAN...	235		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176525
Q14498-235-	AAAMAN...	235			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q14498-313-unknown	GFELAG...	313		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19517
Q14498-313-unknown	GFELAG...	313		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149611
Q14498-313-unknown	GFELAG...	313		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150180
Q14498-332-unknown	ASSASS...	332		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165237
Q14498-332-unknown	ASSASS...	332		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165238
Q14498-332-	ASSASS...	332			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q14498-332-	ASSASS...	332			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q14498-332-	ASSASS...	332			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14498-332-	ASSASS...	332			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14498-332-	ASSASS...	332			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q14498-332-	ASSASS...	332			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q14498-332-	ASSASS...	332			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q14498-333-unknown	SSASSF...	333		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170403
Q14498-333-unknown	SSASSF...	333		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170404
Q14498-333-	SSASSF...	333			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14498-334-unknown	SASSFL...	334		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170397
Q14498-334-unknown	SASSFL...	334		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170398
Q14498-334-	SASSFL...	334			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14498-334-	SASSFL...	334			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14498-334-	SASSFL...	334			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q14498-335-unknown	ASSFLD...	335		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170406
Q14498-335-unknown	ASSFLD...	335		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170407
Q14498-335-	ASSFLD...	335			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14498-335-	ASSFLD...	335			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14498-336-unknown	SSFLDS...	336		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173446
Q14498-336-unknown	SSFLDS...	336		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173447
Q14498-336-	SSFLDS...	336			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14498-337-unknown	SFLDSD...	337		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170400
Q14498-337-unknown	SFLDSD...	337		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170401
Q14498-337-	SFLDSD...	337			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14498-337-	SFLDSD...	337			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14498-341-unknown	SDELER...	341		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12231
Q14498-341-unknown	SDELER...	341		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150312
Q14498-341-unknown	SDELER...	341		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150766
Q14498-413-unknown	AAAASV...	413		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14490
Q14498-413-unknown	AAAASV...	413		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151858
Q14498-413-unknown	AAAASV...	413		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152113

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LTGQRV	217	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10288
...LTGQRV	217	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129760
...LTGQRV	217	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130603
...LEQLNG	312	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19517
...LEQLNG	312	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132998
...LEQLNG	312	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133574
...SSFLDS	340	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12231
...SSFLDS	340	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133707
...SSFLDS	340	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134166
...EASALA	412	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14490
...EASALA	412	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135264
...VPSRR	530	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VPSRR	530	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82741
...VPSRR	530	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82740

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	217	GQRV.\|.VLGV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
MEP1B_HUMAN	312	QLNG.\|.GFEL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	340	FLDS.\|.SDEL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	412	SALA.\|.AAAA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)