P0CG38: POTE ankyrin domain family member I

General Information

Protein names	- POTE ankyrin domain family member I
Gene names	POTEI
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P0CG38

10 N-termini

9 C-termini

8 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVAEVDSMPA ASSVKKPFVL RSKMGKWCRH CFPCCRGSGK SNVGTSGDQD DSTMKTLRSK
        70         80         90        100        110        120
MGKWCCHCFP CCRGSGKSNV GTSGDHDDSA MKTLRSKMGK WCCHCFPCCR GSGKSNVGAW
       130        140        150        160        170        180
GDYDDSAFVE PRYHVRREDL DKLHRAAWWG KVARKDLIVM LRDTDVNKQD KQKRTALHLA
       190        200        210        220        230        240
SANGNSGVVK LLLDRRCQLN VLDNKKRTAL TKAVQCQEDE CALMLLEHGT DPNIPDEYGN
       250        260        270        280        290        300
TTLHYAIYNE DKLMAKALLL YGADIESKNK HGLTPLLLGV HEQKQQVVKF LIKKKANLNA
       310        320        330        340        350        360
LDRYGRTALI LAVCCGSASI VSLLLEQNID VSSQDLSGQT AREYAVSSHH HVICQLLSDY
       370        380        390        400        410        420
KEKQMLKISS ENSNPEQDLK LTSEEESQRF KGSENSQPEK MSQEPEINKD GDREVEEEMK
       430        440        450        460        470        480
KHESNNVGLL ENLSNGVTAG NGDDGLIPQR KSRTPENQQF PDNESEEYHR ICELVSDYKE
       490        500        510        520        530        540
KQMPKYSSEN SNPEQDLKLT SEEESQRLKG SENGQPEKRS QEPEINKDGD RELENFMAIE
       550        560        570        580        590        600
EMKKHGSTHV GFPENLTNGA TAGNGDDGLI PPRKSRTPES QQFPDTENEE YHSDEQNDTQ
       610        620        630        640        650        660
KQFCEEQNTG ILHDEILIHE EKQIEVVEKM NSELSLSCKK EKDFLHENST LREEIAMLRL
       670        680        690        700        710        720
ELDTMKHQSQ LRKKKYLEDI ESVKKKNDNL LKALQLNELT MDDDTAVLVI DNGSGMCKAG
       730        740        750        760        770        780
FAGDDAPRAV FPSIVGRPRQ QGMMGGMHQK ESYVGKEAQS KRGILTLKYP MEHGIITNWD
       790        800        810        820        830        840
DMEKIWHHTF YNELRVAPEE HPILLTEAPL NPKANREKMT QIMFETFNTP AMYVAIQAML
       850        860        870        880        890        900
SLYTSGRTTG IVMDSGDGVT HTVPIYDGNA LPHATLRLDL AGRELTDYLM KILTERGYRF
       910        920        930        940        950        960
TTMAEREIVR DIKEKLCYVA LDFEQEMAMA ASSSSLEKSY ELPDGQVITI GNEWFRCPEA
       970        980        990       1000       1010       1020
LFQPCFLGME SCGIHETTFN SIMKSDVDIR KDLYTNTVLS GGTTMYPGMA HRMQKEIAAL
      1030       1040       1050       1060       1070
APSMLKIRII APPKRKYSVW VGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCF

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

10 N-termini - 9 C-termini - 8 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P0CG38-1-unknown	MVAEVD...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P0CG38-709-unknown	VIDNGS...	709	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13952
P0CG38-712-unknown	NGSGMC...	712	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1624
P0CG38-718-unknown	KAGFAG...	718	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15320
P0CG38-719-unknown	AGFAGD...	719	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC9969
P0CG38-729-unknown	AVFPSI...	729	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18637
P0CG38-806-unknown	TEAPLN...	806	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15321
P0CG38-807-unknown	EAPLNP...	807	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15322
P0CG38-917-unknown	CYVALD...	917	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13953
P0CG38-928-	AMAASS...	928		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DTAVLV	708	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13952
...VLVIDN	711	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1624
...GSGMCK	717	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15320
...SGMCKA	718	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9969
...DDAPRA	728	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18637
...HPILLT	805	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15321
...PILLTE	806	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15322
...IKEKLC	916	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13953
...HRKCF	1075	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	708	AVLV.\|.VIDN	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CASP3_HUMAN	711	VIDN.\|.NGSG	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
HTRA2_HUMAN	717	GMCK.\|.KAGF	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAA_HUMAN	718	MCKA.\|.AGFA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
MEP1B_HUMAN	728	APRA.\|.AVFP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
HTRA2_HUMAN	805	ILLT.\|.TEAP	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
HTRA2_HUMAN	806	LLTE.\|.EAPL	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAM_HUMAN	916	EKLC.\|.CYVA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)