Q9H4B7: Tubulin beta-1 chain

General Information

Protein names	- Tubulin beta-1 chain
Gene names	TUBB1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H4B7

7 N-termini

7 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MREIVHIQIG QCGNQIGAKF WEMIGEEHGI DLAGSDRGAS ALQLERISVY YNEAYGRKYV
        70         80         90        100        110        120
PRAVLVDLEP GTMDSIRSSK LGALFQPDSF VHGNSGAGNN WAKGHYTEGA ELIENVLEVV
       130        140        150        160        170        180
RHESESCDCL QGFQIVHSLG GGTGSGMGTL LMNKIREEYP DRIMNSFSVM PSPKVSDTVV
       190        200        210        220        230        240
EPYNAVLSIH QLIENADACF CIDNEALYDI CFRTLKLTTP TYGDLNHLVS LTMSGITTSL
       250        260        270        280        290        300
RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTAQGSQQ YRALSVAELT QQMFDARNTM
       310        320        330        340        350        360
AACDLRRGRY LTVACIFRGK MSTKEVDQQL LSVQTRNSSC FVEWIPNNVK VAVCDIPPRG
       370        380        390        400        410        420
LSMAATFIGN NTAIQEIFNR VSEHFSAMFK RKAFVHWYTS EGMDINEFGE AENNIHDLVS
       430        440        450
EYQQFQDAKA VLEEDEEVTE EAEMEPEDKG H

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 7 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9H4B7-1-unknown	MREIVH...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9H4B7-63-unknown	AVLVDL...	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13681
Q9H4B7-206-unknown	ALYDIC...	206	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13295
Q9H4B7-241-unknown	RFPGQL...	241	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15533
Q9H4B7-252-unknown	KLAVNM...	252	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10547
Q9H4B7-254-unknown	AVNMVP...	254	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15534
Q9H4B7-283-unknown	ALSVAE...	283	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13682

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KYVPRA	62	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13681
...CIDNEA	205	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13295
...ITTSLR	240	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15533
...NADLRK	251	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10547
...DLRKLA	253	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15534
...SQQYRA	282	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13682
...EDKGH	451	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAK_HUMAN	62	VPRA.\|.AVLV	inferred from experiment	unknown	MEROPS	Kummer JA	Bovenschen N et al.:Granzyme K displays highly rest... (S01.146)	19059912,
GRAB_HUMAN	205	DNEA.\|.ALYD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
HTRA2_HUMAN	240	TSLR.\|.RFPG	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAA_HUMAN	251	DLRK.\|.KLAV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
HTRA2_HUMAN	253	RKLA.\|.AVNM	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAK_HUMAN	282	QYRA.\|.ALSV	inferred from experiment	unknown	MEROPS	Kummer JA	Bovenschen N et al.:Granzyme K displays highly rest... (S01.146)	19059912,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)