P49863: Granzyme K
Protein names | - Granzyme K - 3.4.21.- - Fragmentin-3 - Granzyme-3 - NK-tryptase-2 - NK-Tryp-2 |
---|---|
Gene names | GZMK |
Organism | Homo sapiens |
Protease Family | S01.146 |
Protease ID | S01.146 |
Chromosome location | |
UniProt ID | P49863 |
2
N-termini
1
C-termini
0
Cleavages
18
Substrates
Sequence
10 20 30 40 50 60
MTKFSSFSLF FLIVGAYMTH VCFNMEIIGG KEVSPHSRPF MASIQYGGHH VCGGVLIDPQ
70 80 90 100 110 120
WVLTAAHCQY RFTKGQSPTV VLGAHSLSKN EASKQTLEIK KFIPFSRVTS DPQSNDIMLV
130 140 150 160 170 180
KLQTAAKLNK HVKMLHIRSK TSLRSGTKCK VTGWGATDPD SLRPSDTLRE VTVTVLSRKL
190 200 210 220 230 240
CNSQSYYNGD PFITKDMVCA GDAKGQKDSC KGDSGGPLIC KGVFHAIVSG GHECGVATKP
250 260
GIYTLLTKKY QTWIKSNLVP PHTN
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 18 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P49863-25-unknown | MEIIGG... | 25 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P49863-27-unknown | IIGGKE... | 27 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...PPHTN | 264 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
P53_HUMAN | 24 | LWKL.|.LLPE | inferred from experiment | unknown | MEROPS | Fan Z | Hua G et al.:Ignition of p53 bomb sensitizes... (S01.146) | 19201868, |
P53-Isoform3_HUMAN | 24 | LWKL.|.LLPE | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13665 | ||
P53-Isoform2_HUMAN | 24 | LWKL.|.LLPE | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13665 | ||
TBB3_HUMAN | 62 | VPRA.|.AILV | inferred from experiment | unknown | MEROPS | Kummer JA | Bovenschen N et al.:Granzyme K displays highly rest... (S01.146) | 19059912, |
TBB1_HUMAN | 62 | VPRA.|.AVLV | inferred from experiment | unknown | MEROPS | Kummer JA | Bovenschen N et al.:Granzyme K displays highly rest... (S01.146) | 19059912, |
P53-Isoform9_HUMAN | 173 | STKR.|.RALP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13668 | ||
P53-Isoform8_HUMAN | 173 | STKR.|.RALP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13668 | ||
P53-Isoform7_HUMAN | 173 | STKR.|.RALP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13668 | ||
TBB3-Isoform2_HUMAN | 210 | QYRA.|.ALTV | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13679 | ||
P53-Isoform6_HUMAN | 266 | STKR.|.RALP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13668 | ||
P53-Isoform5_HUMAN | 266 | STKR.|.RALP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13668 | ||
P53-Isoform4_HUMAN | 266 | STKR.|.RALP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13668 | ||
TBB3_HUMAN | 282 | QYRA.|.ALTV | inferred from experiment | unknown | MEROPS | Kummer JA | Bovenschen N et al.:Granzyme K displays highly rest... (S01.146) | 19059912, |
TBB1_HUMAN | 282 | QYRA.|.ALSV | inferred from experiment | unknown | MEROPS | Kummer JA | Bovenschen N et al.:Granzyme K displays highly rest... (S01.146) | 19059912, |
P53_HUMAN | 305 | STKR.|.RALP | inferred from experiment | unknown | MEROPS | Fan Z | Hua G et al.:Ignition of p53 bomb sensitizes... (S01.146) | 19201868, |
P53-Isoform3_HUMAN | 305 | STKR.|.RALP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13668 | ||
P53-Isoform2_HUMAN | 305 | STKR.|.RALP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC13668 | ||
TERA_HUMAN | 713 | RERQ.|.QTNP | inferred from experiment | unknown | MEROPS | Fan Z | Guo Y et al.:Valosin-containing protein clea... (S01.146) | 20876349, |