TopFIND 4.0

P49863: Granzyme K

General Information

Protein names
- Granzyme K
- 3.4.21.-
- Fragmentin-3
- Granzyme-3
- NK-tryptase-2
- NK-Tryp-2

Gene names GZMK
Organism Homo sapiens
Protease Family S01.146
Protease ID S01.146
Chromosome location
UniProt ID P49863

2

N-termini

1

C-termini

0

Cleavages

18

Substrates

Sequence

        10         20         30         40         50         60 
MTKFSSFSLF FLIVGAYMTH VCFNMEIIGG KEVSPHSRPF MASIQYGGHH VCGGVLIDPQ 
        70         80         90        100        110        120 
WVLTAAHCQY RFTKGQSPTV VLGAHSLSKN EASKQTLEIK KFIPFSRVTS DPQSNDIMLV 
       130        140        150        160        170        180 
KLQTAAKLNK HVKMLHIRSK TSLRSGTKCK VTGWGATDPD SLRPSDTLRE VTVTVLSRKL 
       190        200        210        220        230        240 
CNSQSYYNGD PFITKDMVCA GDAKGQKDSC KGDSGGPLIC KGVFHAIVSG GHECGVATKP 
       250        260    
GIYTLLTKKY QTWIKSNLVP PHTN

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 18 Substrates

N-termini

    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P49863-25-unknown MEIIGG... 25 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P49863-27-unknown IIGGKE... 27 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PPHTN 264 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates