Q9UQ35: Serine/arginine repetitive matrix protein 2
Protein names | - Serine/arginine repetitive matrix protein 2 - 300 kDa nuclear matrix antigen - Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa - SR-related nuclear matrix protein of 300 kDa - Ser/Arg-related nuclear matrix protein of 300 kDa - Splicing coactivator subunit SRm300 - Tax-responsive enhancer element-binding protein 803 - TaxREB803 |
---|---|
Gene names | SRRM2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9UQ35 |
42
N-termini
13
C-termini
12
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MYNGIGLPTP RGSGTNGYVQ RNLSLVRGRR GERPDYKGEE ELRRLEAALV KRPNPDILDH
70 80 90 100 110 120
ERKRRVELRC LELEEMMEEQ GYEEQQIQEK VATFRLMLLE KDVNPGGKEE TPGQRPAVTE
130 140 150 160 170 180
THQLAELNEK KNERLRAAFG ISDSYVDGSS FDPQRRAREA KQPAPEPPKP YSLVRESSSS
190 200 210 220 230 240
RSPTPKQKKK KKKKDRGRRS ESSSPRRERK KSSKKKKHRS ESESKKRKHR SPTPKSKRKS
250 260 270 280 290 300
KDKKRKRSRS TTPAPKSRRA HRSTSADSAS SSDTSRSRSR SAAAKTHTTA LAGRSPSPAS
310 320 330 340 350 360
GRRGEGDAPF SEPGTTSTQR PSSPETATKQ PSSPYEDKDK DKKEKSATRP SPSPERSSTG
370 380 390 400 410 420
PEPPAPTPLL AERHGGSPQP LATTPLSQEP VNPPSEASPT RDRSPPKSPE KLPQSSSSES
430 440 450 460 470 480
SPPSPQPTKV SRHASSSPES PKPAPAPGSH REISSSPTSK NRSHGRAKRD KSHSHTPSRR
490 500 510 520 530 540
MGRSRSPATA KRGRSRSRTP TKRGHSRSRS PQWRRSRSAQ RWGRSRSPQR RGRSRSPQRP
550 560 570 580 590 600
GWSRSRNTQR RGRSRSARRG RSHSRSPATR GRSRSRTPAR RGRSRSRTPA RRRSRSRTPT
610 620 630 640 650 660
RRRSRSRTPA RRGRSRSRTP ARRRSRTRSP VRRRSRSRSP ARRSGRSRSR TPARRGRSRS
670 680 690 700 710 720
RTPARRGRSR SRTPARRSGR SRSRTPARRG RSRSRTPRRG RSRSRSLVRR GRSHSRTPQR
730 740 750 760 770 780
RGRSGSSSER KNKSRTSQRR SRSNSSPEMK KSRISSRRSR SLSSPRSKAK SRLSLRRSLS
790 800 810 820 830 840
GSSPCPKQKS QTPPRRSRSG SSQPKAKSRT PPRRSRSSSS PPPKQKSKTP SRQSHSSSSP
850 860 870 880 890 900
HPKVKSGTPP RQGSITSPQA NEQSVTPQRR SCFESSPDPE LKSRTPSRHS CSGSSPPRVK
910 920 930 940 950 960
SSTPPRQSPS RSSSPQPKVK AIISPRQRSH SGSSSPSPSR VTSRTTPRRS RSVSPCSNVE
970 980 990 1000 1010 1020
SRLLPRYSHS GSSSPDTKVK PETPPRQSHS GSISPYPKVK AQTPPGPSLS GSKSPCPQEK
1030 1040 1050 1060 1070 1080
SKDSLVQSCP GSLSLCAGVK SSTPPGESYF GVSSLQLKGQ SQTSPDHRSD TSSPEVRQSH
1090 1100 1110 1120 1130 1140
SESPSLQSKS QTSPKGGRSR SSSPVTELAS RSPIRQDRGE FSASPMLKSG MSPEQSRFQS
1150 1160 1170 1180 1190 1200
DSSSYPTVDS NSLLGQSRLE TAESKEKMAL PPQEDATASP PRQKDKFSPF PVQDRPESSL
1210 1220 1230 1240 1250 1260
VFKDTLRTPP RERSGAGSSP ETKEQNSALP TSSQDEELME VVEKSEEPAG QILSHLSSEL
1270 1280 1290 1300 1310 1320
KEMSTSNFES SPEVEERPAV SLTLDQSQSQ ASLEAVEVPS MASSWGGPHF SPEHKELSNS
1330 1340 1350 1360 1370 1380
PLRENSFGSP LEFRNSGPLG TEMNTGFSSE VKEDLNGPFL NQLETDPSLD MKEQSTRSSG
1390 1400 1410 1420 1430 1440
HSSSELSPDA VEKAGMSSNQ SISSPVLDAV PRTPSRERSS SASSPEMKDG LPRTPSRRSR
1450 1460 1470 1480 1490 1500
SGSSPGLRDG SGTPSRHSLS GSSPGMKDIP RTPSRGRSEC DSSPEPKALP QTPRPRSRSP
1510 1520 1530 1540 1550 1560
SSPELNNKCL TPQRERSGSE SSVDQKTVAR TPLGQRSRSG SSQELDVKPS ASPQERSESD
1570 1580 1590 1600 1610 1620
SSPDSKAKTR TPLRQRSRSG SSPEVDSKSR LSPRRSRSGS SPEVKDKPRA APRAQSGSDS
1630 1640 1650 1660 1670 1680
SPEPKAPAPR ALPRRSRSGS SSKGRGPSPE GSSSTESSPE HPPKSRTARR GSRSSPEPKT
1690 1700 1710 1720 1730 1740
KSRTPPRRRS SRSSPELTRK ARLSRRSRSA SSSPETRSRT PPRHRRSPSV SSPEPAEKSR
1750 1760 1770 1780 1790 1800
SSRRRRSASS PRTKTTSRRG RSPSPKPRGL QRSRSRSRRE KTRTTRRRDR SGSSQSTSRR
1810 1820 1830 1840 1850 1860
RQRSRSRSRV TRRRRGGSGY HSRSPARQES SRTSSRRRRG RSRTPPTSRK RSRSRTSPAP
1870 1880 1890 1900 1910 1920
WKRSRSRASP ATHRRSRSRT PLISRRRSRS RTSPVSRRRS RSRTSVTRRR SRSRASPVSR
1930 1940 1950 1960 1970 1980
RRSRSRTPPV TRRRSRSRTP TTRRRSRSRT PPVTRRRSRS RTPPVTRRRS RSRTSPITRR
1990 2000 2010 2020 2030 2040
RSRSRTSPVT RRRSRSRTSP VTRRRSRSRT SPVTRRRSRS RTPPAIRRRS RSRTPLLPRK
2050 2060 2070 2080 2090 2100
RSRSRSPLAI RRRSRSRTPR TARGKRSLTR SPPAIRRRSA SGSSSDRSRS ATPPATRNHS
2110 2120 2130 2140 2150 2160
GSRTPPVALN SSRMSCFSRP SMSPTPLDRC RSPGMLEPLG SSRTPMSVLQ QAGGSMMDGP
2170 2180 2190 2200 2210 2220
GPRIPDHQRT SVPENHAQSR IALALTAISL GTARPPPSMS AAGLAARMSQ VPAPVPLMSL
2230 2240 2250 2260 2270 2280
RTAPAANLAS RIPAASAAAM NLASARTPAI PTAVNLADSR TPAAAAAMNL ASPRTAVAPS
2290 2300 2310 2320 2330 2340
AVNLADPRTP TAPAVNLAGA RTPAALAALS LTGSGTPPTA ANYPSSSRTP QAPASANLVG
2350 2360 2370 2380 2390 2400
PRSAHATAPV NIAGSRTAAA LAPASLTSAR MAPALSGANL TSPRVPLSAY ERVSGRTSPP
2410 2420 2430 2440 2450 2460
LLDRARSRTP PSAPSQSRMT SERAPSPSSR MGQAPSQSLL PPAQDQPRSP VPSAFSDQSR
2470 2480 2490 2500 2510 2520
CLIAQTTPVA GSQSLSSGAV ATTTSSAGDH NGMLSVPAPG VPHSDVGEPP ASTGAQQPSA
2530 2540 2550 2560 2570 2580
LAALQPAKER RSSSSSSSSS SSSSSSSSSS SSSSSSGSSS SDSEGSSLPV QPEVALKRVP
2590 2600 2610 2620 2630 2640
SPTPAPKEAV REGRPPEPTP AKRKRRSSSS SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS
2650 2660 2670 2680 2690 2700
SSSSSSSSPS PAKPGPQALP KPASPKKPPP GERRSRSPRK PIDSLRDSRS LSYSPVERRR
2710 2720 2730 2740 2750
PSPQPSPRDQ QSSSSERGSR RGQRGDSRSP SHKRRRETPS PRPMRHRSSR SP
Isoforms
- Isoform 2 of Serine/arginine repetitive matrix protein 2 - Isoform 3 of Serine/arginine repetitive matrix protein 2Sequence View
10 20 30 40 50 60
MYNGIGLPTP RGSGTNGYVQ RNLSLVRGRR GERPDYKGEE ELRRLEAALV KRPNPDILDH
70 80 90 100 110 120
ERKRRVELRC LELEEMMEEQ GYEEQQIQEK VATFRLMLLE KDVNPGGKEE TPGQRPAVTE
130 140 150 160 170 180
THQLAELNEK KNERLRAAFG ISDSYVDGSS FDPQRRAREA KQPAPEPPKP YSLVRESSSS
190 200 210 220 230 240
RSPTPKQKKK KKKKDRGRRS ESSSPRRERK KSSKKKKHRS ESESKKRKHR SPTPKSKRKS
250 260 270 280 290 300
KDKKRKRSRS TTPAPKSRRA HRSTSADSAS SSDTSRSRSR SAAAKTHTTA LAGRSPSPAS
310 320 330 340 350 360
GRRGEGDAPF SEPGTTSTQR PSSPETATKQ PSSPYEDKDK DKKEKSATRP SPSPERSSTG
370 380 390 400 410 420
PEPPAPTPLL AERHGGSPQP LATTPLSQEP VNPPSEASPT RDRSPPKSPE KLPQSSSSES
430 440 450 460 470 480
SPPSPQPTKV SRHASSSPES PKPAPAPGSH REISSSPTSK NRSHGRAKRD KSHSHTPSRR
490 500 510 520 530 540
MGRSRSPATA KRGRSRSRTP TKRGHSRSRS PQWRRSRSAQ RWGRSRSPQR RGRSRSPQRP
550 560 570 580 590 600
GWSRSRNTQR RGRSRSARRG RSHSRSPATR GRSRSRTPAR RGRSRSRTPA RRRSRSRTPT
610 620 630 640 650 660
RRRSRSRTPA RRGRSRSRTP ARRRSRTRSP VRRRSRSRSP ARRSGRSRSR TPARRGRSRS
670 680 690 700 710 720
RTPARRGRSR SRTPARRSGR SRSRTPARRG RSRSRTPRRG RSRSRSLVRR GRSHSRTPQR
730 740 750 760 770 780
RGRSGSSSER KNKSRTSQRR SRSNSSPEMK KSRISSRRSR SLSSPRSKAK SRLSLRRSLS
790 800 810 820 830 840
GSSPCPKQKS QTPPRRSRSG SSQPKAKSRT PPRRSRSSSS PPPKQKSKTP SRQSHSSSSP
850 860 870 880 890 900
HPKVKSGTPP RQGSITSPQA NEQSVTPQRR SCFESSPDPE LKSRTPSRHS CSGSSPPRVK
910 920 930 940 950 960
SSTPPRQSPS RSSSPQPKVK AIISPRQRSH SGSSSPSPSR VTSRTTPRRS RSVSPCSNVE
970 980 990 1000 1010 1020
SRLLPRYSHS GSSSPDTKVK PETPPRQSHS GSISPYPKVK AQTPPGPSLS GSKSPCPQEK
1030 1040 1050 1060 1070 1080
SKDSLVQSCP GSLSLCAGVK SSTPPGESYF GVSSLQLKGQ SQTSPDHRSD TSSPEVRQSH
1090 1100 1110 1120 1130 1140
SESPSLQSKS QTSPKGGRSR SSSPVTELAS RSPIRQDRGE FSASPMLKSG MSPEQSRFQS
1150 1160 1170 1180 1190 1200
DSSSYPTVDS NSLLGQSRLE TAESKEKMAL PPQEDATASP PRQKDKFSPF PVQDRPESSL
1210 1220 1230 1240 1250 1260
VFKDTLRTPP RERSGAGSSP ETKEQNSALP TSSQDEELME VVEKSEEPAG QILSHLSSEL
1270 1280 1290 1300 1310 1320
KEMSTSNFES SPEVEERPAV SLTLDQSQSQ ASLEAVEVPS MASSWGGPHF SPEHKELSNS
1330 1340 1350 1360 1370 1380
PLRENSFGSP LEFRNSGPLG TEMNTGFSSE VKEDLNGPFL NQLETDPSLD MKEQSTRSSG
1390 1400 1410 1420 1430 1440
HSSSELSPDA VEKAGMSSNQ SISSPVLDAV PRTPSRERSS SASSPEMKDG LPRTPSRRSR
1450 1460 1470 1480 1490 1500
SGSSPGLRDG SGTPSRHSLS GSSPGMKDIP RTPSRGRSEC DSSPEPKALP QTPRPRSRSP
1510 1520 1530 1540 1550 1560
SSPELNNKCL TPQRERSGSE SSVDQKTVAR TPLGQRSRSG SSQELDVKPS ASPQERSESD
1570 1580 1590 1600 1610 1620
SSPDSKAKTR TPLRQRSRSG SSPEVDSKSR LSPRRSRSGS SPEVKDKPRA APRAQSGSDS
1630 1640 1650 1660 1670 1680
SPEPKAPAPR ALPRRSRSGS SSKGRGPSPE GSSSTESSPE HPPKSRTARR GSRSSPEPKT
1690 1700 1710 1720 1730 1740
KSRTPPRRRS SRSSPELTRK ARLSRRSRSA SSSPETRSRT PPRHRRSPSV SSPEPAEKSR
1750 1760 1770 1780 1790 1800
SSRRRRSASS PRTKTTSRRG RSPSPKPRGL QRSRSRSRRE KTRTTRRRDR SGSSQSTSRR
1810 1820 1830 1840 1850 1860
RQRSRSRSRV TRRRRGGSGY HSRSPARQES SRTSSRRRRG RSRTPPTSRK RSRSRTSPAP
1870 1880 1890 1900 1910 1920
WKRSRSRASP ATHRRSRSRT PLISRRRSRS RTSPVSRRRS RSRTSVTRRR SRSRASPVSR
1930 1940 1950 1960 1970 1980
RRSRSRTPPV TRRRSRSRTP TTRRRSRSRT PPVTRRRSRS RTPPVTRRRS RSRTSPITRR
1990 2000 2010 2020 2030 2040
RSRSRTSPVT RRRSRSRTSP VTRRRSRSRT SPVTRRRSRS RTPPAIRRRS RSRTPLLPRK
2050 2060 2070 2080 2090 2100
RSRSRSPLAI RRRSRSRTPR TARGKRSLTR SPPAIRRRSA SGSSSDRSRS ATPPATRNHS
2110 2120 2130 2140 2150 2160
GSRTPPVALN SSRMSCFSRP SMSPTPLDRC RSPGMLEPLG SSRTPMSVLQ QAGGSMMDGP
2170 2180 2190 2200 2210 2220
GPRIPDHQRT SVPENHAQSR IALALTAISL GTARPPPSMS AAGLAARMSQ VPAPVPLMSL
2230 2240 2250 2260 2270 2280
RTAPAANLAS RIPAASAAAM NLASARTPAI PTAVNLADSR TPAAAAAMNL ASPRTAVAPS
2290 2300 2310 2320 2330 2340
AVNLADPRTP TAPAVNLAGA RTPAALAALS LTGSGTPPTA ANYPSSSRTP QAPASANLVG
2350 2360 2370 2380 2390 2400
PRSAHATAPV NIAGSRTAAA LAPASLTSAR MAPALSGANL TSPRVPLSAY ERVSGRTSPP
2410 2420 2430 2440 2450 2460
LLDRARSRTP PSAPSQSRMT SERAPSPSSR MGQAPSQSLL PPAQDQPRSP VPSAFSDQSR
2470 2480 2490 2500 2510 2520
CLIAQTTPVA GSQSLSSGAV ATTTSSAGDH NGMLSVPAPG VPHSDVGEPP ASTGAQQPSA
2530 2540 2550 2560 2570 2580
LAALQPAKER RSSSSSSSSS SSSSSSSSSS SSSSSSGSSS SDSEGSSLPV QPEVALKRVP
2590 2600 2610 2620 2630 2640
SPTPAPKEAV REGRPPEPTP AKRKRRSSSS SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS
2650 2660 2670 2680 2690 2700
SSSSSSSSPS PAKPGPQALP KPASPKKPPP GERRSRSPRK PIDSLRDSRS LSYSPVERRR
2710 2720 2730 2740 2750
PSPQPSPRDQ QSSSSERGSR RGQRGDSRSP SHKRRRETPS PRPMRHRSSR SP
10 20 30 40 50 60
MYNGIGLPTP RGSGTNGYVQ RNLSLVRGRR GERPDYKGEE ELRRLEAALV KRPNPDILDH
70 80 90 100 110 120
ERKRRVELRC LELEEMMEEQ GYEEQQIQEK VATFRLMLLE KDVNPGGKEE TPGQRPAVTE
130 140 150 160 170 180
THQLAELNEK KNERLRAAFG ISDSYVDGSS FDPQRRAREA KQPAPEPPKP YSLVRESSSS
190 200 210 220 230 240
RSPTPKQKKK KKKKDRGRRS ESSSPRRERK KSSKKKKHRS ESESKKRKHR SPTPKSKRKS
250 260 270 280 290 300
KDKKRKRSRS TTPAPKSRRA HRSTSADSAS SSDTSRSRSR SAAAKTHTTA LAGRSPSPAS
310 320 330 340 350 360
GRRGEGDAPF SEPGTTSTQR PSSPETATKQ PSSPYEDKDK DKKEKSATRP SPSPERSSTG
370 380 390 400 410 420
PEPPAPTPLL AERHGGSPQP LATTPLSQEP VNPPSEASPT RDRSPPKSPE KLPQSSSSES
430 440 450 460 470 480
SPPSPQPTKV SRHASSSPES PKPAPAPGSH REISSSPTSK NRSHGRAKRD KSHSHTPSRR
490 500 510 520 530 540
MGRSRSPATA KRGRSRSRTP TKRGHSRSRS PQWRRSRSAQ RWGRSRSPQR RGRSRSPQRP
550 560 570 580 590 600
GWSRSRNTQR RGRSRSARRG RSHSRSPATR GRSRSRTPAR RGRSRSRTPA RRRSRSRTPT
610 620 630 640 650 660
RRRSRSRTPA RRGRSRSRTP ARRRSRTRSP VRRRSRSRSP ARRSGRSRSR TPARRGRSRS
670 680 690 700 710 720
RTPARRGRSR SRTPARRSGR SRSRTPARRG RSRSRTPRRG RSRSRSLVRR GRSHSRTPQR
730 740 750 760 770 780
RGRSGSSSER KNKSRTSQRR SRSNSSPEMK KSRISSRRSR SLSSPRSKAK SRLSLRRSLS
790 800 810 820 830 840
GSSPCPKQKS QTPPRRSRSG SSQPKAKSRT PPRRSRSSSS PPPKQKSKTP SRQSHSSSSP
850 860 870 880 890 900
HPKVKSGTPP RQGSITSPQA NEQSVTPQRR SCFESSPDPE LKSRTPSRHS CSGSSPPRVK
910 920 930 940 950 960
SSTPPRQSPS RSSSPQPKVK AIISPRQRSH SGSSSPSPSR VTSRTTPRRS RSVSPCSNVE
970 980 990 1000 1010 1020
SRLLPRYSHS GSSSPDTKVK PETPPRQSHS GSISPYPKVK AQTPPGPSLS GSKSPCPQEK
1030 1040 1050 1060 1070 1080
SKDSLVQSCP GSLSLCAGVK SSTPPGESYF GVSSLQLKGQ SQTSPDHRSD TSSPEVRQSH
1090 1100 1110 1120 1130 1140
SESPSLQSKS QTSPKGGRSR SSSPVTELAS RSPIRQDRGE FSASPMLKSG MSPEQSRFQS
1150 1160 1170 1180 1190 1200
DSSSYPTVDS NSLLGQSRLE TAESKEKMAL PPQEDATASP PRQKDKFSPF PVQDRPESSL
1210 1220 1230 1240 1250 1260
VFKDTLRTPP RERSGAGSSP ETKEQNSALP TSSQDEELME VVEKSEEPAG QILSHLSSEL
1270 1280 1290 1300 1310 1320
KEMSTSNFES SPEVEERPAV SLTLDQSQSQ ASLEAVEVPS MASSWGGPHF SPEHKELSNS
1330 1340 1350 1360 1370 1380
PLRENSFGSP LEFRNSGPLG TEMNTGFSSE VKEDLNGPFL NQLETDPSLD MKEQSTRSSG
1390 1400 1410 1420 1430 1440
HSSSELSPDA VEKAGMSSNQ SISSPVLDAV PRTPSRERSS SASSPEMKDG LPRTPSRRSR
1450 1460 1470 1480 1490 1500
SGSSPGLRDG SGTPSRHSLS GSSPGMKDIP RTPSRGRSEC DSSPEPKALP QTPRPRSRSP
1510 1520 1530 1540 1550 1560
SSPELNNKCL TPQRERSGSE SSVDQKTVAR TPLGQRSRSG SSQELDVKPS ASPQERSESD
1570 1580 1590 1600 1610 1620
SSPDSKAKTR TPLRQRSRSG SSPEVDSKSR LSPRRSRSGS SPEVKDKPRA APRAQSGSDS
1630 1640 1650 1660 1670 1680
SPEPKAPAPR ALPRRSRSGS SSKGRGPSPE GSSSTESSPE HPPKSRTARR GSRSSPEPKT
1690 1700 1710 1720 1730 1740
KSRTPPRRRS SRSSPELTRK ARLSRRSRSA SSSPETRSRT PPRHRRSPSV SSPEPAEKSR
1750 1760 1770 1780 1790 1800
SSRRRRSASS PRTKTTSRRG RSPSPKPRGL QRSRSRSRRE KTRTTRRRDR SGSSQSTSRR
1810 1820 1830 1840 1850 1860
RQRSRSRSRV TRRRRGGSGY HSRSPARQES SRTSSRRRRG RSRTPPTSRK RSRSRTSPAP
1870 1880 1890 1900 1910 1920
WKRSRSRASP ATHRRSRSRT PLISRRRSRS RTSPVSRRRS RSRTSVTRRR SRSRASPVSR
1930 1940 1950 1960 1970 1980
RRSRSRTPPV TRRRSRSRTP TTRRRSRSRT PPVTRRRSRS RTPPVTRRRS RSRTSPITRR
1990 2000 2010 2020 2030 2040
RSRSRTSPVT RRRSRSRTSP VTRRRSRSRT SPVTRRRSRS RTPPAIRRRS RSRTPLLPRK
2050 2060 2070 2080 2090 2100
RSRSRSPLAI RRRSRSRTPR TARGKRSLTR SPPAIRRRSA SGSSSDRSRS ATPPATRNHS
2110 2120 2130 2140 2150 2160
GSRTPPVALN SSRMSCFSRP SMSPTPLDRC RSPGMLEPLG SSRTPMSVLQ QAGGSMMDGP
2170 2180 2190 2200 2210 2220
GPRIPDHQRT SVPENHAQSR IALALTAISL GTARPPPSMS AAGLAARMSQ VPAPVPLMSL
2230 2240 2250 2260 2270 2280
RTAPAANLAS RIPAASAAAM NLASARTPAI PTAVNLADSR TPAAAAAMNL ASPRTAVAPS
2290 2300 2310 2320 2330 2340
AVNLADPRTP TAPAVNLAGA RTPAALAALS LTGSGTPPTA ANYPSSSRTP QAPASANLVG
2350 2360 2370 2380 2390 2400
PRSAHATAPV NIAGSRTAAA LAPASLTSAR MAPALSGANL TSPRVPLSAY ERVSGRTSPP
2410 2420 2430 2440 2450 2460
LLDRARSRTP PSAPSQSRMT SERAPSPSSR MGQAPSQSLL PPAQDQPRSP VPSAFSDQSR
2470 2480 2490 2500 2510 2520
CLIAQTTPVA GSQSLSSGAV ATTTSSAGDH NGMLSVPAPG VPHSDVGEPP ASTGAQQPSA
2530 2540 2550 2560 2570 2580
LAALQPAKER RSSSSSSSSS SSSSSSSSSS SSSSSSGSSS SDSEGSSLPV QPEVALKRVP
2590 2600 2610 2620 2630 2640
SPTPAPKEAV REGRPPEPTP AKRKRRSSSS SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS
2650 2660 2670 2680 2690 2700
SSSSSSSSPS PAKPGPQALP KPASPKKPPP GERRSRSPRK PIDSLRDSRS LSYSPVERRR
2710 2720 2730 2740 2750
PSPQPSPRDQ QSSSSERGSR RGQRGDSRSP SHKRRRETPS PRPMRHRSSR SP
Protein Neighborhood
Domains & Features
42 N-termini - 13 C-termini - 12 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9UQ35-1-Acetylation | MYNGIG... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q9UQ35-1-Acetylation | MYNGIG... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
Q9UQ35-1-Acetylation | MYNGIG... | 1 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
Q9UQ35-1-Acetylation | MYNGIG... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
Q9UQ35-1-Acetylation | MYNGIG... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt109036 | ||
Q9UQ35-1-unknown | MYNGIG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90706 | |||
Q9UQ35-4-unknown | GIGLPT... | 4 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173121 | |||
Q9UQ35-4- | GIGLPT... | 4 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-80-unknown | QGYEEQ... | 80 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13573 | |||
Q9UQ35-80-unknown | QGYEEQ... | 80 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt141276 | |||
Q9UQ35-91-unknown | VATFRL... | 91 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
Q9UQ35-91-unknown | VATFRL... | 91 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt196815 | |||
Q9UQ35-96-unknown | LMLLEK... | 96 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10596 | |||
Q9UQ35-96-unknown | LMLLEK... | 96 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142177 | |||
Q9UQ35-97- | MLLEKD... | 97 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
Q9UQ35-97- | MLLEKD... | 97 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q9UQ35-97- | MLLEKD... | 97 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-97-unknown | MLLEKD... | 97 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90707 | |||
Q9UQ35-97-unknown | MLLEKD... | 97 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
Q9UQ35-97-unknown | MLLEKD... | 97 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q9UQ35-97-unknown | MLLEKD... | 97 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q9UQ35-97-unknown | MLLEKD... | 97 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt100652 | |||
Q9UQ35-113-unknown | GQRPAV... | 113 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176571 | |||
Q9UQ35-113-unknown | GQRPAV... | 113 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176572 | |||
Q9UQ35-113- | GQRPAV... | 113 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q9UQ35-117- | AVTETH... | 117 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-117-unknown | AVTETH... | 117 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170374 | |||
Q9UQ35-117-unknown | AVTETH... | 117 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170375 | |||
Q9UQ35-144-unknown | SYVDGS... | 144 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13575 | |||
Q9UQ35-144-unknown | SYVDGS... | 144 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt138941 | |||
Q9UQ35-144-unknown | SYVDGS... | 144 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144473 | |||
Q9UQ35-148-unknown | GSSFDP... | 148 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt166476 | |||
Q9UQ35-148-unknown | GSSFDP... | 148 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt166477 | |||
Q9UQ35-148- | GSSFDP... | 148 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9UQ35-148- | GSSFDP... | 148 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-148- | GSSFDP... | 148 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9UQ35-148- | GSSFDP... | 148 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q9UQ35-150-unknown | SFDPQR... | 150 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13578 | |||
Q9UQ35-150-unknown | SFDPQR... | 150 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139439 | |||
Q9UQ35-150-unknown | SFDPQR... | 150 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144706 | |||
Q9UQ35-415-unknown | SSSSES... | 415 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15148 | |||
Q9UQ35-415-unknown | SSSSES... | 415 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152244 | |||
Q9UQ35-1142-unknown | SSSYPT... | 1142 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13581 | |||
Q9UQ35-1142-unknown | SSSYPT... | 1142 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157491 | |||
Q9UQ35-1144- | SYPTVD... | 1144 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9UQ35-1144- | SYPTVD... | 1144 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-1144-unknown | SYPTVD... | 1144 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt166470 | |||
Q9UQ35-1150-unknown | SNSLLG... | 1150 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q9UQ35-1150-unknown | SNSLLG... | 1150 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162164 | |||
Q9UQ35-1150- | SNSLLG... | 1150 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
Q9UQ35-1150- | SNSLLG... | 1150 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_CD95 | 23264352 | |||
Q9UQ35-1150- | SNSLLG... | 1150 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
Q9UQ35-1150- | SNSLLG... | 1150 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-1150- | SNSLLG... | 1150 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9UQ35-1150- | SNSLLG... | 1150 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9UQ35-1150- | SNSLLG... | 1150 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
Q9UQ35-1194-unknown | DRPESS... | 1194 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19865 | |||
Q9UQ35-1194-unknown | DRPESS... | 1194 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157666 | |||
Q9UQ35-1227- | SALPTS... | 1227 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-1227- | SALPTS... | 1227 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9UQ35-1227- | SALPTS... | 1227 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9UQ35-1227-unknown | SALPTS... | 1227 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt172080 | |||
Q9UQ35-1295- | AVEVPS... | 1295 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9UQ35-1295-unknown | AVEVPS... | 1295 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174988 | |||
Q9UQ35-1326- | SFGSPL... | 1326 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9UQ35-1326- | SFGSPL... | 1326 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-1326- | SFGSPL... | 1326 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9UQ35-1326- | SFGSPL... | 1326 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q9UQ35-1326- | SFGSPL... | 1326 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9UQ35-1326- | SFGSPL... | 1326 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q9UQ35-1326-unknown | SFGSPL... | 1326 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt166474 | |||
Q9UQ35-1390-unknown | AVEKAG... | 1390 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13583 | |||
Q9UQ35-1390-unknown | AVEKAG... | 1390 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158011 | |||
Q9UQ35-1397-unknown | SSNQSI... | 1397 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15150 | |||
Q9UQ35-1397-unknown | SSNQSI... | 1397 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158030 | |||
Q9UQ35-1401- | SISSPV... | 1401 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9UQ35-1401- | SISSPV... | 1401 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9UQ35-1401-unknown | SISSPV... | 1401 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt166479 | |||
Q9UQ35-1561-unknown | SSPDSK... | 1561 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2350 | |||
Q9UQ35-1561-unknown | SSPDSK... | 1561 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158275 | |||
Q9UQ35-2187- | AISLGT... | 2187 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9UQ35-2187- | AISLGT... | 2187 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-2189- | SLGTAR... | 2189 | Subtiligase Based Positive Selection | Wells | THP_untreated | 23264352 | |||
Q9UQ35-2192- | TARPPP... | 2192 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9UQ35-2192- | TARPPP... | 2192 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-2310-unknown | SLTGSG... | 2310 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15152 | |||
Q9UQ35-2343-unknown | SAHATA... | 2343 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q9UQ35-2343- | SAHATA... | 2343 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q9UQ35-2343- | SAHATA... | 2343 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UQ35-2343- | SAHATA... | 2343 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9UQ35-2343- | SAHATA... | 2343 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9UQ35-2357-unknown | TAAALA... | 2357 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10598 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EMMEEQ | 79 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13573 | |||
...EMMEEQ | 79 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt124439 | |||
...VATFRL | 95 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10596 | |||
...VATFRL | 95 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125365 | |||
...FGISDS | 143 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13575 | |||
...FGISDS | 143 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122008 | |||
...FGISDS | 143 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127738 | |||
...YVDGSS | 149 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13578 | |||
...YVDGSS | 149 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122526 | |||
...YVDGSS | 149 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127974 | |||
...EKLPQS | 414 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15148 | |||
...EKLPQS | 414 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt135654 | |||
...RFQSDS | 1141 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13581 | |||
...RFQSDS | 1141 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140989 | |||
...PFPVQD | 1193 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19865 | |||
...PFPVQD | 1193 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141165 | |||
...ELSPDA | 1389 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13583 | |||
...ELSPDA | 1389 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141506 | |||
...EKAGMS | 1396 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15150 | |||
...EKAGMS | 1396 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141525 | |||
...RSESDS | 1560 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2350 | |||
...RSESDS | 1560 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141771 | |||
...ALAALS | 2309 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15152 | |||
...IAGSRT | 2356 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10598 | |||
...SSRSP | 2752 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...SSRSP | 2752 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt86324 |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|