Q5SY80: Cation channel sperm-associated protein subunit epsilon {ECO:0000250|UniProtKB:P0DP43}
Protein names | - Cation channel sperm-associated protein subunit epsilon {ECO:0000250|UniProtKB:P0DP43} - CatSper-epsilon {ECO:0000250|UniProtKB:P0DP43} - CatSperepsilon {ECO:0000250|UniProtKB:P0DP43} |
---|---|
Gene names | C1orf101 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q5SY80 |
4
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSAREVAVLL LWLSCYGSAL WRYSTNSPNY RIFSTRSTIK LEYEGTLFTE WSVPETCFVL
70 80 90 100 110 120
NKSSPTTELR CSSPGVHAIK PIVTGPDEEE RYLFVESSHT CFLWYYRVRH FFNNFTQLIT
130 140 150 160 170 180
VWAYDPESAD PDELLGNAEE PSINSIVLST QMATLGQKPV IHTVLKRKVY SSNEKMRRGT
190 200 210 220 230 240
WRIVVPMTKD DALKEIRGNQ VTFQDCFIAD FLILLTFPLL TIPEIPGYLP ISSPRGSQLM
250 260 270 280 290 300
ASWDACVVAS AVLVTDMETF HTTDSFKSWT RIRVPPDILS DDERRSVAHV ILSRDGIVFL
310 320 330 340 350 360
INGVLYIKSF RGFIRLGGIV NLPDGGITGI SSRKWCWVNY LLKAKGRRST FAVWTENEIY
370 380 390 400 410 420
LGSILLKFAR LVTTTELKNI LSLSVTATLT IDRVEYTGHP LEIAVFLNYC TVCNVTKKIF
430 440 450 460 470 480
LVIYNEDTKQ WVSQDFTLDA PIDSVTMPHF TFSALPGLLL WNKHSIYYCY HNFTFTGILQ
490 500 510 520 530 540
TPAGHGNLSM LSNDSIIHEV FIDYYGDILV KMENNVIFYS KINTRDAVKL HLWTNYTTRA
550 560 570 580 590 600
FIFLSTSGQT YFLYALDDGT IQIQDYPLHL EAQSIAFTTK DKCPYMAFHN NVAHVFYFLD
610 620 630 640 650 660
KGEALTVWTQ IVYPENTGLY VIVESYGPKI LQESHEISFE AAFGYCTKTL TLTFYQNVDY
670 680 690 700 710 720
ERISDYFETQ DKHTGLVLVQ FRPSEYSKAC PIAQKVFQIA VGCDDKKFIA IKGFSKKGCH
730 740 750 760 770 780
HHDFSYVIEK SYLRHQPSKN LRVRYIWGEY GCPLRLDFTE KFQPVVQLFD DNGYVKDVEA
790 800 810 820 830 840
NFIVWEIHGR DDYSFNNTMA QSGCLHEAQT WKSMIELNKH LPLEEVWGPE NYKHCFSYAI
850 860 870 880 890 900
GKPGDLNQPY EIINSSNGNH IFWPMGHSGM YVFRVKILDP NYSFCNLTAM FAIETFGLIP
910 920 930 940 950
SPSVYLVASF LFVLMLLFFT ILVLSYFRYM RIYRRYIYEP LHKPQRKRKK N
Isoforms
- Isoform 2 of Uncharacterized protein C1orf101 - Isoform 3 of Uncharacterized protein C1orf101 - Isoform 2 of Cation channel sperm-associated protein subunit epsilon - Isoform 3 of Cation channel sperm-associated protein subunit epsilonSequence View
10 20 30 40 50 60
MSAREVAVLL LWLSCYGSAL WRYSTNSPNY RIFSTRSTIK LEYEGTLFTE WSVPETCFVL
70 80 90 100 110 120
NKSSPTTELR CSSPGVHAIK PIVTGPDEEE RYLFVESSHT CFLWYYRVRH FFNNFTQLIT
130 140 150 160 170 180
VWAYDPESAD PDELLGNAEE PSINSIVLST QMATLGQKPV IHTVLKRKVY SSNEKMRRGT
190 200 210 220 230 240
WRIVVPMTKD DALKEIRGNQ VTFQDCFIAD FLILLTFPLL TIPEIPGYLP ISSPRGSQLM
250 260 270 280 290 300
ASWDACVVAS AVLVTDMETF HTTDSFKSWT RIRVPPDILS DDERRSVAHV ILSRDGIVFL
310 320 330 340 350 360
INGVLYIKSF RGFIRLGGIV NLPDGGITGI SSRKWCWVNY LLKAKGRRST FAVWTENEIY
370 380 390 400 410 420
LGSILLKFAR LVTTTELKNI LSLSVTATLT IDRVEYTGHP LEIAVFLNYC TVCNVTKKIF
430 440 450 460 470 480
LVIYNEDTKQ WVSQDFTLDA PIDSVTMPHF TFSALPGLLL WNKHSIYYCY HNFTFTGILQ
490 500 510 520 530 540
TPAGHGNLSM LSNDSIIHEV FIDYYGDILV KMENNVIFYS KINTRDAVKL HLWTNYTTRA
550 560 570 580 590 600
FIFLSTSGQT YFLYALDDGT IQIQDYPLHL EAQSIAFTTK DKCPYMAFHN NVAHVFYFLD
610 620 630 640 650 660
KGEALTVWTQ IVYPENTGLY VIVESYGPKI LQESHEISFE AAFGYCTKTL TLTFYQNVDY
670 680 690 700 710 720
ERISDYFETQ DKHTGLVLVQ FRPSEYSKAC PIAQKVFQIA VGCDDKKFIA IKGFSKKGCH
730 740 750 760 770 780
HHDFSYVIEK SYLRHQPSKN LRVRYIWGEY GCPLRLDFTE KFQPVVQLFD DNGYVKDVEA
790 800 810 820 830 840
NFIVWEIHGR DDYSFNNTMA QSGCLHEAQT WKSMIELNKH LPLEEVWGPE NYKHCFSYAI
850 860 870 880 890 900
GKPGDLNQPY EIINSSNGNH IFWPMGHSGM YVFRVKILDP NYSFCNLTAM FAIETFGLIP
910 920 930 940 950
SPSVYLVASF LFVLMLLFFT ILVLSYFRYM RIYRRYIYEP LHKPQRKRKK N
10 20 30 40 50 60
MSAREVAVLL LWLSCYGSAL WRYSTNSPNY RIFSTRSTIK LEYEGTLFTE WSVPETCFVL
70 80 90 100 110 120
NKSSPTTELR CSSPGVHAIK PIVTGPDEEE RYLFVESSHT CFLWYYRVRH FFNNFTQLIT
130 140 150 160 170 180
VWAYDPESAD PDELLGNAEE PSINSIVLST QMATLGQKPV IHTVLKRKVY SSNEKMRRGT
190 200 210 220 230 240
WRIVVPMTKD DALKEIRGNQ VTFQDCFIAD FLILLTFPLL TIPEIPGYLP ISSPRGSQLM
250 260 270 280 290 300
ASWDACVVAS AVLVTDMETF HTTDSFKSWT RIRVPPDILS DDERRSVAHV ILSRDGIVFL
310 320 330 340 350 360
INGVLYIKSF RGFIRLGGIV NLPDGGITGI SSRKWCWVNY LLKAKGRRST FAVWTENEIY
370 380 390 400 410 420
LGSILLKFAR LVTTTELKNI LSLSVTATLT IDRVEYTGHP LEIAVFLNYC TVCNVTKKIF
430 440 450 460 470 480
LVIYNEDTKQ WVSQDFTLDA PIDSVTMPHF TFSALPGLLL WNKHSIYYCY HNFTFTGILQ
490 500 510 520 530 540
TPAGHGNLSM LSNDSIIHEV FIDYYGDILV KMENNVIFYS KINTRDAVKL HLWTNYTTRA
550 560 570 580 590 600
FIFLSTSGQT YFLYALDDGT IQIQDYPLHL EAQSIAFTTK DKCPYMAFHN NVAHVFYFLD
610 620 630 640 650 660
KGEALTVWTQ IVYPENTGLY VIVESYGPKI LQESHEISFE AAFGYCTKTL TLTFYQNVDY
670 680 690 700 710 720
ERISDYFETQ DKHTGLVLVQ FRPSEYSKAC PIAQKVFQIA VGCDDKKFIA IKGFSKKGCH
730 740 750 760 770 780
HHDFSYVIEK SYLRHQPSKN LRVRYIWGEY GCPLRLDFTE KFQPVVQLFD DNGYVKDVEA
790 800 810 820 830 840
NFIVWEIHGR DDYSFNNTMA QSGCLHEAQT WKSMIELNKH LPLEEVWGPE NYKHCFSYAI
850 860 870 880 890 900
GKPGDLNQPY EIINSSNGNH IFWPMGHSGM YVFRVKILDP NYSFCNLTAM FAIETFGLIP
910 920 930 940 950
SPSVYLVASF LFVLMLLFFT ILVLSYFRYM RIYRRYIYEP LHKPQRKRKK N
10 20 30 40 50 60
MSAREVAVLL LWLSCYGSAL WRYSTNSPNY RIFSTRSTIK LEYEGTLFTE WSVPETCFVL
70 80 90 100 110 120
NKSSPTTELR CSSPGVHAIK PIVTGPDEEE RYLFVESSHT CFLWYYRVRH FFNNFTQLIT
130 140 150 160 170 180
VWAYDPESAD PDELLGNAEE PSINSIVLST QMATLGQKPV IHTVLKRKVY SSNEKMRRGT
190 200 210 220 230 240
WRIVVPMTKD DALKEIRGNQ VTFQDCFIAD FLILLTFPLL TIPEIPGYLP ISSPRGSQLM
250 260 270 280 290 300
ASWDACVVAS AVLVTDMETF HTTDSFKSWT RIRVPPDILS DDERRSVAHV ILSRDGIVFL
310 320 330 340 350 360
INGVLYIKSF RGFIRLGGIV NLPDGGITGI SSRKWCWVNY LLKAKGRRST FAVWTENEIY
370 380 390 400 410 420
LGSILLKFAR LVTTTELKNI LSLSVTATLT IDRVEYTGHP LEIAVFLNYC TVCNVTKKIF
430 440 450 460 470 480
LVIYNEDTKQ WVSQDFTLDA PIDSVTMPHF TFSALPGLLL WNKHSIYYCY HNFTFTGILQ
490 500 510 520 530 540
TPAGHGNLSM LSNDSIIHEV FIDYYGDILV KMENNVIFYS KINTRDAVKL HLWTNYTTRA
550 560 570 580 590 600
FIFLSTSGQT YFLYALDDGT IQIQDYPLHL EAQSIAFTTK DKCPYMAFHN NVAHVFYFLD
610 620 630 640 650 660
KGEALTVWTQ IVYPENTGLY VIVESYGPKI LQESHEISFE AAFGYCTKTL TLTFYQNVDY
670 680 690 700 710 720
ERISDYFETQ DKHTGLVLVQ FRPSEYSKAC PIAQKVFQIA VGCDDKKFIA IKGFSKKGCH
730 740 750 760 770 780
HHDFSYVIEK SYLRHQPSKN LRVRYIWGEY GCPLRLDFTE KFQPVVQLFD DNGYVKDVEA
790 800 810 820 830 840
NFIVWEIHGR DDYSFNNTMA QSGCLHEAQT WKSMIELNKH LPLEEVWGPE NYKHCFSYAI
850 860 870 880 890 900
GKPGDLNQPY EIINSSNGNH IFWPMGHSGM YVFRVKILDP NYSFCNLTAM FAIETFGLIP
910 920 930 940 950
SPSVYLVASF LFVLMLLFFT ILVLSYFRYM RIYRRYIYEP LHKPQRKRKK N
10 20 30 40 50 60
MSAREVAVLL LWLSCYGSAL WRYSTNSPNY RIFSTRSTIK LEYEGTLFTE WSVPETCFVL
70 80 90 100 110 120
NKSSPTTELR CSSPGVHAIK PIVTGPDEEE RYLFVESSHT CFLWYYRVRH FFNNFTQLIT
130 140 150 160 170 180
VWAYDPESAD PDELLGNAEE PSINSIVLST QMATLGQKPV IHTVLKRKVY SSNEKMRRGT
190 200 210 220 230 240
WRIVVPMTKD DALKEIRGNQ VTFQDCFIAD FLILLTFPLL TIPEIPGYLP ISSPRGSQLM
250 260 270 280 290 300
ASWDACVVAS AVLVTDMETF HTTDSFKSWT RIRVPPDILS DDERRSVAHV ILSRDGIVFL
310 320 330 340 350 360
INGVLYIKSF RGFIRLGGIV NLPDGGITGI SSRKWCWVNY LLKAKGRRST FAVWTENEIY
370 380 390 400 410 420
LGSILLKFAR LVTTTELKNI LSLSVTATLT IDRVEYTGHP LEIAVFLNYC TVCNVTKKIF
430 440 450 460 470 480
LVIYNEDTKQ WVSQDFTLDA PIDSVTMPHF TFSALPGLLL WNKHSIYYCY HNFTFTGILQ
490 500 510 520 530 540
TPAGHGNLSM LSNDSIIHEV FIDYYGDILV KMENNVIFYS KINTRDAVKL HLWTNYTTRA
550 560 570 580 590 600
FIFLSTSGQT YFLYALDDGT IQIQDYPLHL EAQSIAFTTK DKCPYMAFHN NVAHVFYFLD
610 620 630 640 650 660
KGEALTVWTQ IVYPENTGLY VIVESYGPKI LQESHEISFE AAFGYCTKTL TLTFYQNVDY
670 680 690 700 710 720
ERISDYFETQ DKHTGLVLVQ FRPSEYSKAC PIAQKVFQIA VGCDDKKFIA IKGFSKKGCH
730 740 750 760 770 780
HHDFSYVIEK SYLRHQPSKN LRVRYIWGEY GCPLRLDFTE KFQPVVQLFD DNGYVKDVEA
790 800 810 820 830 840
NFIVWEIHGR DDYSFNNTMA QSGCLHEAQT WKSMIELNKH LPLEEVWGPE NYKHCFSYAI
850 860 870 880 890 900
GKPGDLNQPY EIINSSNGNH IFWPMGHSGM YVFRVKILDP NYSFCNLTAM FAIETFGLIP
910 920 930 940 950
SPSVYLVASF LFVLMLLFFT ILVLSYFRYM RIYRRYIYEP LHKPQRKRKK N
Protein Neighborhood
Domains & Features
4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q5SY80-1-unknown | MSAREV... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68887 | |||
Q5SY80-20-unknown | LWRYST... | 20 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q5SY80-20-unknown | LWRYST... | 20 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt112403 | |||
Q5SY80-152-unknown | MATLGQ... | 152 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68888 | |||
Q5SY80-152-unknown | MATLGQ... | 152 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt97219 | |||
Q5SY80-192-unknown | ALKEIR... | 192 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10341 | |||
Q5SY80-192-unknown | ALKEIR... | 192 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt138415 | |||
Q5SY80-192-unknown | ALKEIR... | 192 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt146315 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...MTKDDA | 191 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10341 | |||
...MTKDDA | 191 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt121456 | |||
...MTKDDA | 191 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt129618 | |||
...KRKKN | 951 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...KRKKN | 951 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt64506 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAA_HUMAN | 191 | KDDA.|.ALKE | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:The substrate specificity profi... (S01.135) | 20536382, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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