22 N-termini - 14 C-termini - 19 Cleavages - 0 Substrates

N-termini

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...EFEVME	11	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC929
	...DAGLKE	44	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC937
	...DAGLKE	44	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121816
	...DAGLKE	44	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121817
	...DAGLKE	44	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121818
	...DAGLKE	44	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121819
	...DAGLKE	44	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121820
	...DAGLKE	44	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt153849
	...DAGLKE	44	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt153850
	...PGSSDP	421	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1636
	...PGSSDP	421	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3043
	...PGSSDP	421	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2801
	...PGSSDP	421	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt135778
	...KSGDRS	511	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC9972
	...KSGDRS	511	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt125667
	...KSGDRS	511	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127452
	...KSGDRS	511	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127453
	...KSGDRS	511	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt128678
	...KSGDRS	511	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt128680
	...KSGDRS	511	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129752
	...KSGDRS	511	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129753
	...VAVVRT	547	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC943
	...VAVVRT	547	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127442
	...VAVVRT	547	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt128940
	...VAVVRT	547	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt128941
	...VAVVRT	547	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129945
	...VAVVRT	547	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129946
	...VAVVRT	547	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131134
	...VAVVRT	547	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131135
	...VAVVRT	547	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt137601
	...MPDLKN	571	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC952
	...MPDLKN	571	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt128478
	...MPDLKN	571	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129809
	...MPDLKN	571	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129810
	...MPDLKN	571	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130952
	...MPDLKN	571	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130953
	...MPDLKN	571	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132029
	...MPDLKN	571	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132030
	...MPDLKN	571	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt137891
	...LKNVKS	574	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC961
	...LKNVKS	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt128610
	...LKNVKS	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129882
	...LKNVKS	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129883
	...LKNVKS	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131054
	...LKNVKS	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131055
	...LKNVKS	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132128
	...LKNVKS	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132129
	...LKNVKS	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt137928
	...TENLKH	584	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC970
	...TENLKH	584	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt128980
	...TENLKH	584	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130296
	...TENLKH	584	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130297
	...TENLKH	584	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131409
	...TENLKH	584	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131410
	...TENLKH	584	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132466
	...TENLKH	584	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132468
	...TENLKH	584	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt138052
	...VQIVYK	627	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC979
	...VQIVYK	627	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131932
	...VQIVYK	627	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132790
	...VQIVYK	627	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133536
	...VQIVYK	627	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt138685
	...LGNIHH	646	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17269
	...LGNIHH	646	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130027
	...LGNIHH	646	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131509
	...LGNIHH	646	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132504
	...LGNIHH	646	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132563
	...LGNIHH	646	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133224
	...LGNIHH	646	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133281
	...LGNIHH	646	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133926
	...LGNIHH	646	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt138908
	...QVEVKS	657	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC984
	...QVEVKS	657	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130544
	...QVEVKS	657	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131885
	...QVEVKS	657	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132771
	...QVEVKS	657	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132822
	...QVEVKS	657	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133523
	...QVEVKS	657	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133561
	...QVEVKS	657	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134168
	...QVEVKS	657	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt139060
	...AEIVYK	711	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC993
	...AEIVYK	711	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132517
	...AEIVYK	711	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133432
	...AEIVYK	711	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134022
	...AEIVYK	711	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134067
	...AEIVYK	711	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134692
	...AEIVYK	711	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134739
	...AEIVYK	711	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt135330
	...AEIVYK	711	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt139601
	...IDMVDS	738	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1638
	...IDMVDS	738	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1137
	...IDMVDS	738	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2487
	...IDMVDS	738	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3045
	...IDMVDS	738	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2803
	...IDMVDS	738	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133185
	...IDMVDS	738	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133980
	...IDMVDS	738	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134639
	...IDMVDS	738	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134680
	...IDMVDS	738	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt135259
	...IDMVDS	738	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt135300
	...IDMVDS	738	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt135779
	...IDMVDS	738	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt139769
	...AKQGL	758	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...AKQGL	758	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87162
	...AKQGL	758	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87161
	...AKQGL	758	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87163
	...AKQGL	758	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87165
	...AKQGL	758	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87164
	...AKQGL	758	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87166
	...AKQGL	758	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87167
	...AKQGL	758	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87168

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CAN2_HUMAN	11	EVME.|.EDHA	inferred from experiment	unknown	MEROPS	Ksiezak-Reding H	Yang LS et al.:Calpain-induced proteolysis of ... (C02.002)	7588778,
CAN2_HUMAN	44	GLKE.|.ESPL	inferred from experiment	unknown	MEROPS	Ksiezak-Reding H	Yang LS et al.:Calpain-induced proteolysis of ... (C02.002)	7588778,
CASP3_HUMAN	421	SSDP.|.PLIQ	inferred from experiment	unknown	MEROPS	Cryns VL	Gamblin TC et al.:Caspase cleavage of tau: linkin... (C14.001)	12888622,
CASP8_HUMAN	421	SSDP.|.PLIQ	inferred from experiment	unknown	MEROPS	Cryns VL	Gamblin TC et al.:Caspase cleavage of tau: linkin... (C14.001)	12888622,
CASP7_HUMAN	421	SSDP.|.PLIQ	inferred from experiment	unknown	MEROPS	Cryns VL	Gamblin TC et al.:Caspase cleavage of tau: linkin... (C14.001)	12888622,
GRAA_HUMAN	511	GDRS.|.SGYS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CAN2_HUMAN	547	VVRT.|.TPPK	inferred from experiment	unknown	MEROPS	Ksiezak-Reding H	Yang LS et al.:Calpain-induced proteolysis of ... (C02.002)	7588778,
CAN2_HUMAN	571	DLKN.|.NVKS	inferred from experiment	unknown	MEROPS	Ksiezak-Reding H	Yang LS et al.:Calpain-induced proteolysis of ... (C02.002)	7588778,
CAN2_HUMAN	574	NVKS.|.SKIG	inferred from experiment	unknown	MEROPS	Ksiezak-Reding H	Yang LS et al.:Calpain-induced proteolysis of ... (C02.002)	7588778,
CAN2_HUMAN	584	NLKH.|.HQPG	inferred from experiment	unknown	MEROPS	Ksiezak-Reding H	Yang LS et al.:Calpain-induced proteolysis of ... (C02.002)	7588778,
CAN2_HUMAN	627	IVYK.|.KPVD	inferred from experiment	unknown	MEROPS	Ksiezak-Reding H	Yang LS et al.:Calpain-induced proteolysis of ... (C02.002)	7588778,
MEP1A_HUMAN	646	NIHH.|.HKPG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CAN2_HUMAN	657	EVKS.|.SEKL	inferred from experiment	unknown	MEROPS	Ksiezak-Reding H	Yang LS et al.:Calpain-induced proteolysis of ... (C02.002)	7588778,
CAN2_HUMAN	711	IVYK.|.KSPV	inferred from experiment	unknown	MEROPS	Ksiezak-Reding H	Yang LS et al.:Calpain-induced proteolysis of ... (C02.002)	7588778,
CASP3_HUMAN	738	MVDS.|.SPQL	inferred from experiment	unknown	MEROPS	Cattaneo A	Fasulo L et al.:The neuronal microtubule-associ... (C14.003)	10899937,
CASP1_HUMAN	738	MVDS.|.SPQL	inferred from experiment	unknown	MEROPS	Cryns VL	Gamblin TC et al.:Caspase cleavage of tau: linkin... (C14.001)	12888622,
CASP6_HUMAN	738	MVDS.|.SPQL	inferred from experiment	unknown	MEROPS	Cryns VL	Gamblin TC et al.:Caspase cleavage of tau: linkin... (C14.001)	12888622,
CASP8_HUMAN	738	MVDS.|.SPQL	inferred from experiment	unknown	MEROPS	Cryns VL	Gamblin TC et al.:Caspase cleavage of tau: linkin... (C14.001)	12888622,
CASP7_HUMAN	738	MVDS.|.SPQL	inferred from experiment	unknown	MEROPS	Cryns VL	Gamblin TC et al.:Caspase cleavage of tau: linkin... (C14.001)	12888622,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)