TopFIND 4.0

P55212: Caspase-6

General Information

Protein names
- Caspase-6
- CASP-6
- 3.4.22.59
- Apoptotic protease Mch-2
- Caspase-6 subunit p18
- Caspase-6 subunit p11

Gene names CASP6
Organism Homo sapiens
Protease Family C14.005
Protease ID C14.005
Chromosome location
UniProt ID P55212

3

N-termini

4

C-termini

6

Cleavages

371

Substrates

Sequence

        10         20         30         40         50         60 
MSSASGLRRG HPAGGEENMT ETDAFYKREM FDPAEKYKMD HRRRGIALIF NHERFFWHLT 
        70         80         90        100        110        120 
LPERRGTCAD RDNLTRRFSD LGFEVKCFND LKAEELLLKI HEVSTVSHAD ADCFVCVFLS 
       130        140        150        160        170        180 
HGEGNHIYAY DAKIEIQTLT GLFKGDKCHS LVGKPKIFII QACRGNQHDV PVIPLDVVDN 
       190        200        210        220        230        240 
QTEKLDTNIT EVDAASVYTL PAGADFLMCY SVAEGYYSHR ETVNGSWYIQ DLCEMLGKYG 
       250        260        270        280        290    
SSLEFTELLT LVNRKVSQRR VDFCKDPSAI GKKQVPCFAS MLTKKLHFFP KSN

Isoforms

- Isoform Beta of Caspase-6

Sequence View

        10         20         30         40         50         60 
MSSASGLRRG HPAGGEENMT ETDAFYKREM FDPAEKYKMD HRRRGIALIF NHERFFWHLT 
        70         80         90        100        110        120 
LPERRGTCAD RDNLTRRFSD LGFEVKCFND LKAEELLLKI HEVSTVSHAD ADCFVCVFLS 
       130        140        150        160        170        180 
HGEGNHIYAY DAKIEIQTLT GLFKGDKCHS LVGKPKIFII QACRGNQHDV PVIPLDVVDN 
       190        200        210        220        230        240 
QTEKLDTNIT EVDAASVYTL PAGADFLMCY SVAEGYYSHR ETVNGSWYIQ DLCEMLGKYG 
       250        260        270        280        290    
SSLEFTELLT LVNRKVSQRR VDFCKDPSAI GKKQVPCFAS MLTKKLHFFP KSN



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(REFRESH)

Directness:


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Evidence Codes:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 6 Cleavages - 371 Substrates

N-termini

C-termini

Cleavages

Substrates