P04406: Glyceraldehyde-3-phosphate dehydrogenase

General Information

Protein names	- Glyceraldehyde-3-phosphate dehydrogenase - GAPDH - 1.2.1.12 - Peptidyl-cysteine S-nitrosylase GAPDH - 2.6.99.-
Gene names	GAPDH
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P04406

65 N-termini

27 C-termini

29 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGKVKVGVNG FGRIGRLVTR AAFNSGKVDI VAINDPFIDL NYMVYMFQYD STHGKFHGTV
        70         80         90        100        110        120
KAENGKLVIN GNPITIFQER DPSKIKWGDA GAEYVVESTG VFTTMEKAGA HLQGGAKRVI
       130        140        150        160        170        180
ISAPSADAPM FVMGVNHEKY DNSLKIISNA SCTTNCLAPL AKVIHDNFGI VEGLMTTVHA
       190        200        210        220        230        240
ITATQKTVDG PSGKLWRDGR GALQNIIPAS TGAAKAVGKV IPELNGKLTG MAFRVPTANV
       250        260        270        280        290        300
SVVDLTCRLE KPAKYDDIKK VVKQASEGPL KGILGYTEHQ VVSSDFNSDT HSSTFDAGAG
       310        320        330
IALNDHFVKL ISWYDNEFGY SNRVVDLMAH MASKE

Isoforms

- Isoform 2 of Glyceraldehyde-3-phosphate dehydrogenase

Sequence View

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Evidence Codes:

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Evidence Names:

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Protein Neighborhood

Domains & Features

65 N-termini - 27 C-termini - 29 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P04406-2-unknown	GKVKVG...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P04406-2-unknown	GKVKVG...	2		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC16803
P04406-2-unknown	GKVKVG...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P04406-2-unknown	GKVKVG...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P04406-2-	GKVKVG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P04406-2-	GKVKVG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04406-2-	GKVKVG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P04406-2-	GKVKVG...	2			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P04406-2-	GKVKVG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P04406-2-	GKVKVG...	2			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P04406-2-	GKVKVG...	2			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P04406-41-unknown	NYMVYM...	41		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P04406-43-unknown	MVYMFQ...	43		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75631
P04406-47-unknown	FQYDST...	47		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7196
P04406-47-unknown	FQYDST...	47		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3370
P04406-47-unknown	FQYDST...	47		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196044
P04406-58-unknown	GTVKAE...	58		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18431
P04406-58-unknown	GTVKAE...	58		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136565
P04406-71-	GNPITI...	71			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P04406-71-	GNPITI...	71			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04406-71-	GNPITI...	71			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P04406-71-	GNPITI...	71			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P04406-71-unknown	GNPITI...	71		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7197
P04406-71-unknown	GNPITI...	71		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137446
P04406-82-unknown	PSKIKW...	82		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2431
P04406-82-unknown	PSKIKW...	82		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138349
P04406-89-unknown	DAGAEY...	89		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18433
P04406-89-unknown	DAGAEY...	89		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138865
P04406-90-	AGAEYV...	90			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04406-90-unknown	AGAEYV...	90		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18435
P04406-90-unknown	AGAEYV...	90		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17091
P04406-90-unknown	AGAEYV...	90		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138939
P04406-92-unknown	AEYVVE...	92		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18437
P04406-92-unknown	AEYVVE...	92		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139137
P04406-93-unknown	EYVVES...	93		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18439
P04406-93-unknown	EYVVES...	93		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139227
P04406-94-unknown	YVVEST...	94		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18441
P04406-94-unknown	YVVEST...	94		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139310
P04406-98-	STGVFT...	98			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P04406-98-	STGVFT...	98			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04406-98-	STGVFT...	98			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P04406-98-	STGVFT...	98			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P04406-98-	STGVFT...	98			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P04406-98-unknown	STGVFT...	98		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166495
P04406-105-unknown	MEKAGA...	105		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177741
P04406-105-	MEKAGA...	105			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P04406-119-	VIISAP...	119			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P04406-119-unknown	VIISAP...	119		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175257
P04406-123-acetylation	APSADA...	123	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P04406-123-acetylation	APSADA...	123	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt181418
P04406-123-unknown	APSADA...	123		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5382
P04406-123-unknown	APSADA...	123		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141325
P04406-130-unknown	MFVMGV...	130		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175259
P04406-130-	MFVMGV...	130			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P04406-134-	GVNHEK...	134			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04406-134-unknown	GVNHEK...	134		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172346
P04406-167-unknown	NFGIVE...	167		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2433
P04406-167-unknown	NFGIVE...	167		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143703
P04406-176-unknown	TTVHAI...	176		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18443
P04406-176-unknown	TTVHAI...	176		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144027
P04406-178-unknown	VHAITA...	178		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3371
P04406-178-unknown	VHAITA...	178		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144108
P04406-180-	AITATQ...	180			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P04406-180-	AITATQ...	180			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P04406-180-unknown	AITATQ...	180		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166493
P04406-180-acetylation	AITATQ...	180	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P04406-180-acetylation	AITATQ...	180	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt181420
P04406-181-unknown	ITATQK...	181		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18445
P04406-181-unknown	ITATQK...	181		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144239
P04406-183-unknown	ATQKTV...	183		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5384
P04406-183-unknown	ATQKTV...	183		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144335
P04406-183-unknown	ATQKTV...	183		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P04406-183-unknown	ATQKTV...	183		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P04406-184-unknown	TQKTVD...	184		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17093
P04406-184-unknown	TQKTVD...	184		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144423
P04406-187-	TVDGPS...	187			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04406-187-	TVDGPS...	187			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P04406-187-unknown	TVDGPS...	187		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173444
P04406-190-unknown	GPSGKL...	190		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1121
P04406-190-unknown	GPSGKL...	190		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144633
P04406-201-	GALQNI...	201			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P04406-201-	GALQNI...	201			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P04406-201-unknown	GALQNI...	201			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P04406-201-unknown	GALQNI...	201		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt159653
P04406-202-unknown	ALQNII...	202		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176485
P04406-202-	ALQNII...	202			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P04406-205-unknown	NIIPAS...	205		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18447
P04406-205-unknown	NIIPAS...	205		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145245
P04406-216-	AVGKVI...	216			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P04406-216-	AVGKVI...	216			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P04406-216-unknown	AVGKVI...	216		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176757
P04406-220-acetylation	VIPELN...	220	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P04406-220-acetylation	VIPELN...	220	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt181422
P04406-234-unknown	RVPTAN...	234			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P04406-234-unknown	RVPTAN...	234		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt159655
P04406-235-unknown	VPTANV...	235		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt181424
P04406-235-unknown	VPTANV...	235		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P04406-235-unknown	VPTANV...	235		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P04406-235-	VPTANV...	235			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P04406-235-acetylation	VPTANV...	235	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P04406-235-acetylation	VPTANV...	235	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt181426
P04406-239-unknown	NVSVVD...	239		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18449
P04406-239-unknown	NVSVVD...	239		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17095
P04406-239-unknown	NVSVVD...	239		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146482
P04406-240-unknown	VSVVDL...	240		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17097
P04406-240-unknown	VSVVDL...	240		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146537
P04406-276-unknown	YTEHQV...	276		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3373
P04406-276-unknown	YTEHQV...	276		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147869
P04406-278-unknown	EHQVVS...	278		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5386
P04406-278-unknown	EHQVVS...	278		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147937
P04406-279-acetylation	HQVVSS...	279	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P04406-279-acetylation	HQVVSS...	279	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt181428
P04406-281-unknown	VVSSDF...	281		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3375
P04406-281-unknown	VVSSDF...	281		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148015
P04406-286-unknown	FNSDTH...	286		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2435
P04406-286-unknown	FNSDTH...	286		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148246
P04406-288-unknown	SDTHSS...	288		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166487
P04406-288-	SDTHSS...	288			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P04406-288-	SDTHSS...	288			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04406-288-	SDTHSS...	288			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P04406-288-	SDTHSS...	288			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P04406-292-unknown	SSTFDA...	292		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166490
P04406-292-	SSTFDA...	292			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P04406-292-	SSTFDA...	292			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P04406-293-unknown	STFDAG...	293		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176483
P04406-293-	STFDAG...	293			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P04406-296-unknown	DAGAGI...	296		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17099
P04406-296-unknown	DAGAGI...	296		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148610

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...YMVYMF	46	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7196
...YMVYMF	46	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3370
...HGKFHG	57	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18431
...KLVING	70	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7197
...KLVING	70	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt120406
...FQERDP	81	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2431
...FQERDP	81	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121386
...KIKWGD	88	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18433
...KIKWGD	88	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121929
...IKWGDA	89	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18435
...IKWGDA	89	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17091
...IKWGDA	89	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122006
...WGDAGA	91	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18437
...WGDAGA	91	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122208
...GDAGAE	92	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18439
...GDAGAE	92	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122302
...DAGAEY	93	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18441
...DAGAEY	93	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122385
...RVIISA	122	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5382
...RVIISA	122	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt124490
...KVIHDN	166	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2433
...KVIHDN	166	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt126946
...VEGLMT	175	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18443
...VEGLMT	175	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127271
...GLMTTV	177	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3371
...GLMTTV	177	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127359
...TTVHAI	180	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18445
...TTVHAI	180	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127492
...VHAITA	182	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5384
...VHAITA	182	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127597
...HAITAT	183	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17093
...HAITAT	183	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127687
...QKTVDG	189	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1121
...QKTVDG	189	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127900
...RGALQN	204	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18447
...RGALQN	204	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt128535
...RVPTAN	238	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18449
...RVPTAN	238	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17095
...RVPTAN	238	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129790
...VPTANV	239	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17097
...VPTANV	239	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129845
...KGILGY	275	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3373
...KGILGY	275	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131224
...ILGYTE	277	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5386
...ILGYTE	277	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131298
...YTEHQV	280	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3375
...YTEHQV	280	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131378
...VVSSDF	285	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2435
...VVSSDF	285	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131612
...HSSTFD	295	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17099
...HSSTFD	295	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131984
...MASKE	335	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...MASKE	335	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt71249
...MASKE	335		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...MASKE	335		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...MASKE	335		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...MASKE	335		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MAP2_HUMAN	1	.\|.GKVK	inferred from experiment	unknown	MEROPS	Wang J	Warder SE et al.:Discovery, identification, and ... (M24.002)	18828628,
CATS_HUMAN	46	VYMF.\|.FQYD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	46	VYMF.\|.FQYD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	57	KFHG.\|.GTVK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATS_HUMAN	70	VING.\|.GNPI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CASP6_HUMAN	81	ERDP.\|.PSKI	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
MEP1B_HUMAN	88	KWGD.\|.DAGA	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	89	WGDA.\|.AGAE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	89	WGDA.\|.AGAE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	91	DAGA.\|.AEYV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	92	AGAE.\|.EYVV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	93	GAEY.\|.YVVE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	122	IISA.\|.APSA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CASP6_HUMAN	166	IHDN.\|.NFGI	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
MEP1B_HUMAN	175	GLMT.\|.TTVH	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATB_HUMAN	177	MTTV.\|.VHAI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	180	VHAI.\|.ITAT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	182	AITA.\|.ATQK	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	183	ITAT.\|.TQKT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CASP1_HUMAN	189	TVDG.\|.GPSG	inferred from experiment	unknown	MEROPS	Saleh M	Shao W et al.:The caspase-1 digestome identif... (C14.001)	17959595,
MEP1B_HUMAN	204	ALQN.\|.NIIP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	238	PTAN.\|.NVSV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	238	PTAN.\|.NVSV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	239	TANV.\|.VSVV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATB_HUMAN	275	ILGY.\|.YTEH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	277	GYTE.\|.EHQV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	280	EHQV.\|.VVSS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CASP6_HUMAN	285	SSDF.\|.FNSD	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
MEP1A_HUMAN	295	STFD.\|.DAGA	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)