Q01826: DNA-binding protein SATB1

General Information

Protein names	- DNA-binding protein SATB1 - Special AT-rich sequence-binding protein 1
Gene names	SATB1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q01826

5 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDHLNEATQG KEHSEMSNNV SDPKGPPAKI ARLEQNGSPL GRGRLGSTGA KMQGVPLKHS
        70         80         90        100        110        120
GHLMKTNLRK GTMLPVFCVV EHYENAIEYD CKEEHAEFVL VRKDMLFNQL IEMALLSLGY
       130        140        150        160        170        180
SHSSAAQAKG LIQVGKWNPV PLSYVTDAPD ATVADMLQDV YHVVTLKIQL HSCPKLEDLP
       190        200        210        220        230        240
PEQWSHTTVR NALKDLLKDM NQSSLAKECP LSQSMISSIV NSTYYANVSA AKCQEFGRWY
       250        260        270        280        290        300
KHFKKTKDMM VEMDSLSELS QQGANHVNFG QQPVPGNTAE QPPSPAQLSH GSQPSVRTPL
       310        320        330        340        350        360
PNLHPGLVST PISPQLVNQQ LVMAQLLNQQ YAVNRLLAQQ SLNQQYLNHP PPVSRSMNKP
       370        380        390        400        410        420
LEQQVSTNTE VSSEIYQWVR DELKRAGISQ AVFARVAFNR TQGLLSEILR KEEDPKTASQ
       430        440        450        460        470        480
SLLVNLRAMQ NFLQLPEAER DRIYQDERER SLNAASAMGP APLISTPPSR PPQVKTATIA
       490        500        510        520        530        540
TERNGKPENN TMNINASIYD EIQQEMKRAK VSQALFAKVA ATKSQGWLCE LLRWKEDPSP
       550        560        570        580        590        600
ENRTLWENLS MIRRFLSLPQ PERDAIYEQE SNAVHHHGDR PPHIIHVPAE QIQQQQQQQQ
       610        620        630        640        650        660
QQQQQQQAPP PPQPQQQPQT GPRLPPRQPT VASPAESDEE NRQKTRPRTK ISVEALGILQ
       670        680        690        700        710        720
SFIQDVGLYP DEEAIQTLSA QLDLPKYTII KFFQNQRYYL KHHGKLKDNS GLEVDVAEYK
       730        740        750        760
EEELLKDLEE SVQDKNTNTL FSVKLEEELS VEGNTDINTD LKD

Isoforms

- Isoform 2 of DNA-binding protein SATB1

Sequence View

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Evidence Codes:

Methodology:

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Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q01826-1-unknown	MDHLNE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q01826-1-unknown	MDHLNE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88894
Q01826-255-	SLSELS...	255		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q01826-255-unknown	SLSELS...	255	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2679
Q01826-255-unknown	SLSELS...	255	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148646
Q01826-266-unknown	HVNFGQ...	266	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173790
Q01826-266-	HVNFGQ...	266		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MVEMDS	254	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2679
...MVEMDS	254	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132021
...TDLKD	763	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TDLKD	763	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84512

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP6_HUMAN	254	EMDS.\|.SLSE	inferred from experiment	unknown	MEROPS	Kohwi-Shigematsu T	Galande S et al.:SATB1 cleavage by caspase 6 dis... (C14.005)	11463840,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)