Q05397: Focal adhesion kinase 1
Protein names | - Focal adhesion kinase 1 - FADK 1 - 2.7.10.2 - Focal adhesion kinase-related nonkinase - FRNK - Protein phosphatase 1 regulatory subunit 71 - PPP1R71 - Protein-tyrosine kinase 2 - p125FAK - pp125FAK |
---|---|
Gene names | PTK2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q05397 |
6
N-termini
3
C-termini
5
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAAAYLDPNL NHTPNSSTKT HLGTGMERSP GAMERVLKVF HYFESNSEPT TWASIIRHGD
70 80 90 100 110 120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
130 140 150 160 170 180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMLEIA DQVDQEIALK LGCLEIRRSY
190 200 210 220 230 240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
250 260 270 280 290 300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFTQVQ
310 320 330 340 350 360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGTSQSFII
370 380 390 400 410 420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
430 440 450 460 470 480
RIELGRCIGE GQFGDVHQGI YMSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
490 500 510 520 530 540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
550 560 570 580 590 600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
610 620 630 640 650 660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
670 680 690 700 710 720
YDPSRRPRFT ELKAQLSTIL EEEKAQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
730 740 750 760 770 780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGITAMAGSI YPGQASLLDQ TDSWNHRPQE
790 800 810 820 830 840
IAMWQPNVED STVLDLRGIG QVLPTHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
850 860 870 880 890 900
RGSIDREDGS LQGPIGNQHI YQPVGKPDPA APPKKPPRPG APGHLGSLAS LSSPADSYNE
910 920 930 940 950 960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
970 980 990 1000 1010 1020
LRTLLATVDE TIPLLPASTH REIEMAQKLL NSDLGELINK MKLAQQYVMT SLQQEYKKQM
1030 1040 1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH
Isoforms
- Isoform 2 of Focal adhesion kinase 1 - Isoform 3 of Focal adhesion kinase 1 - Isoform 4 of Focal adhesion kinase 1 - Isoform 5 of Focal adhesion kinase 1 - Isoform 6 of Focal adhesion kinase 1 - Isoform 7 of Focal adhesion kinase 1Sequence View
10 20 30 40 50 60
MAAAYLDPNL NHTPNSSTKT HLGTGMERSP GAMERVLKVF HYFESNSEPT TWASIIRHGD
70 80 90 100 110 120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
130 140 150 160 170 180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMLEIA DQVDQEIALK LGCLEIRRSY
190 200 210 220 230 240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
250 260 270 280 290 300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFTQVQ
310 320 330 340 350 360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGTSQSFII
370 380 390 400 410 420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
430 440 450 460 470 480
RIELGRCIGE GQFGDVHQGI YMSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
490 500 510 520 530 540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
550 560 570 580 590 600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
610 620 630 640 650 660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
670 680 690 700 710 720
YDPSRRPRFT ELKAQLSTIL EEEKAQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
730 740 750 760 770 780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGITAMAGSI YPGQASLLDQ TDSWNHRPQE
790 800 810 820 830 840
IAMWQPNVED STVLDLRGIG QVLPTHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
850 860 870 880 890 900
RGSIDREDGS LQGPIGNQHI YQPVGKPDPA APPKKPPRPG APGHLGSLAS LSSPADSYNE
910 920 930 940 950 960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
970 980 990 1000 1010 1020
LRTLLATVDE TIPLLPASTH REIEMAQKLL NSDLGELINK MKLAQQYVMT SLQQEYKKQM
1030 1040 1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH
10 20 30 40 50 60
MAAAYLDPNL NHTPNSSTKT HLGTGMERSP GAMERVLKVF HYFESNSEPT TWASIIRHGD
70 80 90 100 110 120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
130 140 150 160 170 180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMLEIA DQVDQEIALK LGCLEIRRSY
190 200 210 220 230 240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
250 260 270 280 290 300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFTQVQ
310 320 330 340 350 360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGTSQSFII
370 380 390 400 410 420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
430 440 450 460 470 480
RIELGRCIGE GQFGDVHQGI YMSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
490 500 510 520 530 540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
550 560 570 580 590 600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
610 620 630 640 650 660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
670 680 690 700 710 720
YDPSRRPRFT ELKAQLSTIL EEEKAQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
730 740 750 760 770 780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGITAMAGSI YPGQASLLDQ TDSWNHRPQE
790 800 810 820 830 840
IAMWQPNVED STVLDLRGIG QVLPTHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
850 860 870 880 890 900
RGSIDREDGS LQGPIGNQHI YQPVGKPDPA APPKKPPRPG APGHLGSLAS LSSPADSYNE
910 920 930 940 950 960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
970 980 990 1000 1010 1020
LRTLLATVDE TIPLLPASTH REIEMAQKLL NSDLGELINK MKLAQQYVMT SLQQEYKKQM
1030 1040 1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH
10 20 30 40 50 60
MAAAYLDPNL NHTPNSSTKT HLGTGMERSP GAMERVLKVF HYFESNSEPT TWASIIRHGD
70 80 90 100 110 120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
130 140 150 160 170 180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMLEIA DQVDQEIALK LGCLEIRRSY
190 200 210 220 230 240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
250 260 270 280 290 300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFTQVQ
310 320 330 340 350 360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGTSQSFII
370 380 390 400 410 420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
430 440 450 460 470 480
RIELGRCIGE GQFGDVHQGI YMSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
490 500 510 520 530 540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
550 560 570 580 590 600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
610 620 630 640 650 660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
670 680 690 700 710 720
YDPSRRPRFT ELKAQLSTIL EEEKAQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
730 740 750 760 770 780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGITAMAGSI YPGQASLLDQ TDSWNHRPQE
790 800 810 820 830 840
IAMWQPNVED STVLDLRGIG QVLPTHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
850 860 870 880 890 900
RGSIDREDGS LQGPIGNQHI YQPVGKPDPA APPKKPPRPG APGHLGSLAS LSSPADSYNE
910 920 930 940 950 960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
970 980 990 1000 1010 1020
LRTLLATVDE TIPLLPASTH REIEMAQKLL NSDLGELINK MKLAQQYVMT SLQQEYKKQM
1030 1040 1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH
10 20 30 40 50 60
MAAAYLDPNL NHTPNSSTKT HLGTGMERSP GAMERVLKVF HYFESNSEPT TWASIIRHGD
70 80 90 100 110 120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
130 140 150 160 170 180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMLEIA DQVDQEIALK LGCLEIRRSY
190 200 210 220 230 240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
250 260 270 280 290 300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFTQVQ
310 320 330 340 350 360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGTSQSFII
370 380 390 400 410 420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
430 440 450 460 470 480
RIELGRCIGE GQFGDVHQGI YMSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
490 500 510 520 530 540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
550 560 570 580 590 600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
610 620 630 640 650 660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
670 680 690 700 710 720
YDPSRRPRFT ELKAQLSTIL EEEKAQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
730 740 750 760 770 780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGITAMAGSI YPGQASLLDQ TDSWNHRPQE
790 800 810 820 830 840
IAMWQPNVED STVLDLRGIG QVLPTHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
850 860 870 880 890 900
RGSIDREDGS LQGPIGNQHI YQPVGKPDPA APPKKPPRPG APGHLGSLAS LSSPADSYNE
910 920 930 940 950 960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
970 980 990 1000 1010 1020
LRTLLATVDE TIPLLPASTH REIEMAQKLL NSDLGELINK MKLAQQYVMT SLQQEYKKQM
1030 1040 1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH
10 20 30 40 50 60
MAAAYLDPNL NHTPNSSTKT HLGTGMERSP GAMERVLKVF HYFESNSEPT TWASIIRHGD
70 80 90 100 110 120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
130 140 150 160 170 180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMLEIA DQVDQEIALK LGCLEIRRSY
190 200 210 220 230 240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
250 260 270 280 290 300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFTQVQ
310 320 330 340 350 360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGTSQSFII
370 380 390 400 410 420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
430 440 450 460 470 480
RIELGRCIGE GQFGDVHQGI YMSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
490 500 510 520 530 540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
550 560 570 580 590 600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
610 620 630 640 650 660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
670 680 690 700 710 720
YDPSRRPRFT ELKAQLSTIL EEEKAQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
730 740 750 760 770 780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGITAMAGSI YPGQASLLDQ TDSWNHRPQE
790 800 810 820 830 840
IAMWQPNVED STVLDLRGIG QVLPTHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
850 860 870 880 890 900
RGSIDREDGS LQGPIGNQHI YQPVGKPDPA APPKKPPRPG APGHLGSLAS LSSPADSYNE
910 920 930 940 950 960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
970 980 990 1000 1010 1020
LRTLLATVDE TIPLLPASTH REIEMAQKLL NSDLGELINK MKLAQQYVMT SLQQEYKKQM
1030 1040 1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH
10 20 30 40 50 60
MAAAYLDPNL NHTPNSSTKT HLGTGMERSP GAMERVLKVF HYFESNSEPT TWASIIRHGD
70 80 90 100 110 120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
130 140 150 160 170 180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMLEIA DQVDQEIALK LGCLEIRRSY
190 200 210 220 230 240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
250 260 270 280 290 300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFTQVQ
310 320 330 340 350 360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGTSQSFII
370 380 390 400 410 420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
430 440 450 460 470 480
RIELGRCIGE GQFGDVHQGI YMSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
490 500 510 520 530 540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
550 560 570 580 590 600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
610 620 630 640 650 660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
670 680 690 700 710 720
YDPSRRPRFT ELKAQLSTIL EEEKAQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
730 740 750 760 770 780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGITAMAGSI YPGQASLLDQ TDSWNHRPQE
790 800 810 820 830 840
IAMWQPNVED STVLDLRGIG QVLPTHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
850 860 870 880 890 900
RGSIDREDGS LQGPIGNQHI YQPVGKPDPA APPKKPPRPG APGHLGSLAS LSSPADSYNE
910 920 930 940 950 960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
970 980 990 1000 1010 1020
LRTLLATVDE TIPLLPASTH REIEMAQKLL NSDLGELINK MKLAQQYVMT SLQQEYKKQM
1030 1040 1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH
Protein Neighborhood
Domains & Features
6 N-termini - 3 C-termini - 5 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q05397-1-unknown | MAAAYL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt74742 | |||
Q05397-2-unknown | MAAAYL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q05397-2-Acetylation | AAAYLD... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q05397-2-Acetylation | AAAYLD... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt111646 | ||
Q05397-693-unknown | MESRRQ... | 693 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt74743 | |||
Q05397-693-unknown | MESRRQ... | 693 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt109604 | |||
Q05397-693-unknown | MESRRQ... | 693 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt109603 | |||
Q05397-705-unknown | SGGSDE... | 705 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2694 | |||
Q05397-705-unknown | SGGSDE... | 705 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11916 | |||
Q05397-705-unknown | SGGSDE... | 705 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt136426 | |||
Q05397-705-unknown | SGGSDE... | 705 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt154019 | |||
Q05397-705-unknown | SGGSDE... | 705 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155898 | |||
Q05397-773-unknown | SWNHRP... | 773 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2062 | |||
Q05397-773-unknown | SWNHRP... | 773 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2929 | |||
Q05397-773-unknown | SWNHRP... | 773 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2698 | |||
Q05397-773-unknown | SWNHRP... | 773 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt141332 | |||
Q05397-773-unknown | SWNHRP... | 773 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt154925 | |||
Q05397-773-unknown | SWNHRP... | 773 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156379 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...TVSWDS | 704 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2694 | |||
...TVSWDS | 704 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11916 | |||
...TVSWDS | 704 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt137439 | |||
...TVSWDS | 704 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139355 | |||
...LDQTDS | 772 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2062 | |||
...LDQTDS | 772 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2929 | |||
...LDQTDS | 772 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2698 | |||
...LDQTDS | 772 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt124498 | |||
...LDQTDS | 772 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt138352 | |||
...LDQTDS | 772 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139858 | |||
...QTRPH | 1052 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...QTRPH | 1052 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt70361 | |||
...QTRPH | 1052 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt70357 | |||
...QTRPH | 1052 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt70360 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CASP6_HUMAN | 704 | SWDS.|.SGGS | inferred from experiment | unknown | MEROPS | Roy S | Gervais FG et al.:Caspases cleave focal adhesion ... (C14.003) | 9642276, |
GRAB_HUMAN | 704 | SWDS.|.SGGS | inferred from experiment | unknown | MEROPS | Roy S | Gervais FG et al.:Caspases cleave focal adhesion ... (C14.003) | 9642276, |
CASP3_HUMAN | 772 | QTDS.|.SWNH | inferred from experiment | unknown | MEROPS | Roy S | Gervais FG et al.:Caspases cleave focal adhesion ... (C14.003) | 9642276, |
CASP7_HUMAN | 772 | QTDS.|.SWNH | inferred from experiment | unknown | MEROPS | Rosen GD | Wen LP et al.:Cleavage of focal adhesion kina... (C14.004) | 9325343, |
CASP6_HUMAN | 772 | QTDS.|.SWNH | inferred from experiment | unknown | MEROPS | Roy S | Gervais FG et al.:Caspases cleave focal adhesion ... (C14.003) | 9642276, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|