Q13077: TNF receptor-associated factor 1

General Information

Protein names	- TNF receptor-associated factor 1 - Epstein-Barr virus-induced protein 6
Gene names	TRAF1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13077

3 N-termini

2 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASSSGSSPR PAPDENEFPF GCPPTVCQDP KEPRALCCAG CLSENPRNGE DQICPKCRGE
        70         80         90        100        110        120
DLQSISPGSR LRTQEKAHPE VAEAGIGCPF AGVGCSFKGS PQSVQEHEVT SQTSHLNLLL
       130        140        150        160        170        180
GFMKQWKARL GCGLESGPMA LEQNLSDLQL QAAVEVAGDL EVDCYRAPCS ESQEELALQH
       190        200        210        220        230        240
FMKEKLLAEL EGKLRVFENI VAVLNKEVEA SHLALATSIH QSQLDRERIL SLEQRVVELQ
       250        260        270        280        290        300
QTLAQKDQAL GKLEQSLRLM EEASFDGTFL WKITNVTRRC HESACGRTVS LFSPAFYTAK
       310        320        330        340        350        360
YGYKLCLRLY LNGDGTGKRT HLSLFIVIMR GEYDALLPWP FRNKVTFMLL DQNNREHAID
       370        380        390        400        410
AFRPDLSSAS FQRPQSETNV ASGCPLFFPL SKLQSPKHAY VKDDTMFLKC IVETST

Isoforms

- Isoform 2 of TNF receptor-associated factor 1

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q13077-1-unknown	MASSSG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q13077-123-unknown	MKQWKA...	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92941
Q13077-164-unknown	CYRAPC...	164	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3114
Q13077-164-unknown	CYRAPC...	164	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2153
Q13077-164-unknown	CYRAPC...	164	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2705
Q13077-164-unknown	CYRAPC...	164	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138493

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DLEVDC	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3114
...DLEVDC	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2153
...DLEVDC	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2705
...DLEVDC	163	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121537
...VETST	416	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VETST	416	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88559

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP8_HUMAN	163	EVDC.\|.CYRA	inferred from experiment	unknown	MEROPS	Tschopp J	Irmler M et al.:Caspase-induced inactivation of... (C14.003)	10692572,
CASP3_HUMAN	163	EVDC.\|.CYRA	inferred from experiment	unknown	MEROPS	Tschopp J	Irmler M et al.:Caspase-induced inactivation of... (C14.003)	10692572,
CASP6_HUMAN	163	EVDC.\|.CYRA	inferred from experiment	unknown	MEROPS	Tschopp J	Irmler M et al.:Caspase-induced inactivation of... (C14.003)	10692572,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)