P31150: Rab GDP dissociation inhibitor alpha

General Information

Protein names	- Rab GDP dissociation inhibitor alpha - Rab GDI alpha - Guanosine diphosphate dissociation inhibitor 1 - GDI-1 - Oligophrenin-2 - Protein XAP-4
Gene names	GDI1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P31150

6 N-termini

6 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDEEYDVIVL GTGLTECILS GIMSVNGKKV LHMDRNPYYG GESSSITPLE ELYKRFQLLE
        70         80         90        100        110        120
GPPESMGRGR DWNVDLIPKF LMANGQLVKM LLYTEVTRYL DFKVVEGSFV YKGGKIYKVP
       130        140        150        160        170        180
STETEALASN LMGMFEKRRF RKFLVFVANF DENDPKTFEG VDPQTTSMRD VYRKFDLGQD
       190        200        210        220        230        240
VIDFTGHALA LYRTDDYLDQ PCLETVNRIK LYSESLARYG KSPYLYPLYG LGELPQGFAR
       250        260        270        280        290        300
LSAIYGGTYM LNKPVDDIIM ENGKVVGVKS EGEVARCKQL ICDPSYIPDR VRKAGQVIRI
       310        320        330        340        350        360
ICILSHPIKN TNDANSCQII IPQNQVNRKS DIYVCMISYA HNVAAQGKYI AIASTTVETT
       370        380        390        400        410        420
DPEKEVEPAL ELLEPIDQKF VAISDLYEPI DDGCESQVFC SCSYDATTHF ETTCNDIKDI
       430        440
YKRMAGTAFD FENMKRKQND VFGEAEQ

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 6 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P31150-1-unknown	MDEEYD...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P31150-7-unknown	VIVLGT...	7	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2551
P31150-155-unknown	PKTFEG...	155	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2552
P31150-354-	STTVET...	354		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P31150-417-unknown	IKDIYK...	417	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2553
P31150-427-unknown	TAFDFE...	427	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7421

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...DEEYDV	6	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2551
...FDENDP	154	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2552
...TTCNDI	416	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2553
...KRMAGT	426	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7421
...GEAEQ	447	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...GEAEQ	447		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...GEAEQ	447		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...GEAEQ	447		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...GEAEQ	447		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP6_HUMAN	6	EYDV.\|.VIVL	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CASP6_HUMAN	154	ENDP.\|.PKTF	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CASP6_HUMAN	416	CNDI.\|.IKDI	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CATS_HUMAN	426	MAGT.\|.TAFD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)