P14635: G2/mitotic-specific cyclin-B1

General Information

Protein names	- G2/mitotic-specific cyclin-B1
Gene names	CCNB1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P14635

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALRVTRNSK INAENKAKIN MAGAKRVPTA PAATSKPGLR PRTALGDIGN KVSEQLQAKM
        70         80         90        100        110        120
PMKKEAKPSA TGKVIDKKLP KPLEKVPMLV PVPVSEPVPE PEPEPEPEPV KEEKLSPEPI
       130        140        150        160        170        180
LVDTASPSPM ETSGCAPAEE DLCQAFSDVI LAVNDVDAED GADPNLCSEY VKDIYAYLRQ
       190        200        210        220        230        240
LEEEQAVRPK YLLGREVTGN MRAILIDWLV QVQMKFRLLQ ETMYMTVSII DRFMQNNCVP
       250        260        270        280        290        300
KKMLQLVGVT AMFIASKYEE MYPPEIGDFA FVTDNTYTKH QIRQMEMKIL RALNFGLGRP
       310        320        330        340        350        360
LPLHFLRRAS KIGEVDVEQH TLAKYLMELT MLDYDMVHFP PSQIAAGAFC LALKILDNGE
       370        380        390        400        410        420
WTPTLQHYLS YTEESLLPVM QHLAKNVVMV NQGLTKHMTV KNKYATSKHA KISTLPQLNS
       430
ALVQDLAKAV AKV

Isoforms

- Isoform 2 of G2/mitotic-specific cyclin-B1

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P14635-1-unknown	MALRVT...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P14635-1-unknown	MALRVT...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt69764
P14635-124-unknown	TASPSP...	124	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2541
P14635-124-unknown	TASPSP...	124	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143677
P14635-185-unknown	QAVRPK...	185	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000426230
P14635-185-unknown	QAVRPK...	185	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt132055
P14635-388-	VMVNQG...	388		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PILVDT	123	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2541
...PILVDT	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126920
...LNFGLG	297	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000426092
...LNFGLG	297	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113022
...AVAKV	433	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AVAKV	433	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65382

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP6_HUMAN	123	LVDT.\|.TASP	inferred from experiment	unknown	MEROPS	Poon RY	Chan YW et al.:Generation of an indestructible... (C14.005)	18820706,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)