87 N-termini - 22 C-termini - 23 Cleavages - 0 Substrates

N-termini

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...DIAALV	8	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14227
	...ALVVDN	11	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1958
	...ALVVDN	11	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1252
	...GSGMCK	17	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15327
	...SGMCKA	18	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10114
	...RHQGVM	43	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC9471
	...VMVGMG	47	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14228
	...MGQKDS	51	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2383
	...MGQKDS	51	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1959
	...MGQKDS	51	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11739
	...HGIVTN	77	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7607
	...VTNWDD	80	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000401032
	...NELRVA	96	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000399487
	...PEEHPV	102	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000393951
	...HPVLLT	105	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15328
	...PVLLTE	106	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15329
	...VTHTVP	163	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000407473
	...IKEKLC	216	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14229
	...KLCYVA	219	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15330
	...YVALDF	222	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2604
	...YVALDF	222	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11740
	...YELPDG	244	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1960
	...YELPDG	244	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1253
	...FLGMES	270	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7608
	...DLYANT	296	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19969
	...KQEYDE	363	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2605
	...KQEYDE	363	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6071
	...HRKCF	375	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	8	AALV.|.VVDN	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CASP3_HUMAN	11	VVDN.|.NGSG	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
CASP1_HUMAN	11	VVDN.|.NGSG	inferred from experiment	unknown	MEROPS	Tsuruo T	Mashima T et al.:Actin cleavage by CPP-32/apopai... (C14.001)	9070648,
HTRA2_HUMAN	17	GMCK.|.KAGF	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAA_HUMAN	18	MCKA.|.AGFA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
ELNE_HUMAN	43	QGVM.|.MVGM	inferred from experiment	unknown	MEROPS	Toyoshima S	Yamashita S et al.:Characterization of a protease ... (S01.131)	11217076,
GRAM_HUMAN	47	VGMG.|.GQKD	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CASP4_HUMAN	51	QKDS.|.SYVG	inferred from experiment	unknown	MEROPS	Wells JA	Agard NJ et al.:Inflammatory stimuli regulate c... (C14.001)	20173201,
CASP3_HUMAN	51	QKDS.|.SYVG	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
GRAB_HUMAN	51	QKDS.|.SYVG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CATS_HUMAN	77	IVTN.|.NWDD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
HTRA2_HUMAN	105	VLLT.|.TEAP	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
HTRA2_HUMAN	106	LLTE.|.EAPL	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAM_HUMAN	216	EKLC.|.CYVA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
HTRA2_HUMAN	219	CYVA.|.ALDF	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
CASP6_HUMAN	222	ALDF.|.FEQE	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
GRAB_HUMAN	222	ALDF.|.FEQE	inferred from experiment	unknown	MEROPS		Merops GRAB_HUMAN -> ACTB_HUMAN @222
GRAB_HUMAN	222	ALDF.|.FEQE	inferred from experiment	unknown	MEROPS	Gevaert K	Plasman K et al.:Probing the efficiency of prote... (S01.010)	21048194,
CASP3_HUMAN	244	LPDG.|.GQVI	inferred from experiment	unknown	MEROPS	Tsuruo T	Mashima T et al.:Actin cleavage by CPP-32/apopai... (C14.001)	9070648,
CASP1_HUMAN	244	LPDG.|.GQVI	inferred from experiment	unknown	MEROPS	Tsuruo T	Mashima T et al.:Actin cleavage by CPP-32/apopai... (C14.001)	9070648,
CATS_HUMAN	270	GMES.|.SCGI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MMP11_HUMAN	296	YANT.|.TVLS	inferred from experiment	unknown	MEROPS		Merops MMP11_HUMAN -> ACTB_HUMAN @296
CASP6_HUMAN	363	EYDE.|.ESGP	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CATL1_HUMAN	363	EYDE.|.ESGP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)