P08670: Vimentin
Protein names | - Vimentin |
---|---|
Gene names | VIM |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P08670 |
47
N-termini
19
C-termini
25
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSTRSVSSSS YRRMFGGPGT ASRPSSSRSY VTTSTRTYSL GSALRPSTSR SLYASSPGGV
70 80 90 100 110 120
YATRSSAVRL RSSVPGVRLL QDSVDFSLAD AINTEFKNTR TNEKVELQEL NDRFANYIDK
130 140 150 160 170 180
VRFLEQQNKI LLAELEQLKG QGKSRLGDLY EEEMRELRRQ VDQLTNDKAR VEVERDNLAE
190 200 210 220 230 240
DIMRLREKLQ EEMLQREEAE NTLQSFRQDV DNASLARLDL ERKVESLQEE IAFLKKLHEE
250 260 270 280 290 300
EIQELQAQIQ EQHVQIDVDV SKPDLTAALR DVRQQYESVA AKNLQEAEEW YKSKFADLSE
310 320 330 340 350 360
AANRNNDALR QAKQESTEYR RQVQSLTCEV DALKGTNESL ERQMREMEEN FAVEAANYQD
370 380 390 400 410 420
TIGRLQDEIQ NMKEEMARHL REYQDLLNVK MALDIEIATY RKLLEGEESR ISLPLPNFSS
430 440 450 460
LNLRETNLDS LPLVDTHSKR TLLIKTVETR DGQVINETSQ HHDDLE
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
47 N-termini - 19 C-termini - 25 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P08670-2-unknown | MSTRSV... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P08670-2-Acetylation | STRSVS... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P08670-5- | SVSSSS... | 5 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-5- | SVSSSS... | 5 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P08670-14- | MFGGPG... | 14 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P08670-14- | MFGGPG... | 14 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P08670-14- | MFGGPG... | 14 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-14-unknown | MFGGPG... | 14 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-14-acetylation | MFGGPG... | 14 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
P08670-16- | GGPGTA... | 16 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-29- | SYVTTS... | 29 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-30- | YVTTST... | 30 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-37-unknown | TYSLGS... | 37 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9954 | |||
P08670-38- | YSLGSA... | 38 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P08670-38-unknown | YSLGSA... | 38 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-41-unknown | GSALRP... | 41 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15319 | |||
P08670-42-unknown | SALRPS... | 42 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7255 | |||
P08670-51-unknown | SLYASS... | 51 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-51- | SLYASS... | 51 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P08670-51- | SLYASS... | 51 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-51- | SLYASS... | 51 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-54- | ASSPGG... | 54 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P08670-54- | ASSPGG... | 54 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-54- | ASSPGG... | 54 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P08670-54- | ASSPGG... | 54 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
P08670-54- | ASSPGG... | 54 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P08670-54- | ASSPGG... | 54 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-54-unknown | ASSPGG... | 54 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-55- | SSPGGV... | 55 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-55- | SSPGGV... | 55 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-83- | SVDFSL... | 83 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-86-unknown | FSLADA... | 86 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1613 | |||
P08670-86-unknown | FSLADA... | 86 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2800 | |||
P08670-86-unknown | FSLADA... | 86 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-86- | FSLADA... | 86 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P08670-86- | FSLADA... | 86 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P08670-86- | FSLADA... | 86 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-86- | FSLADA... | 86 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P08670-86- | FSLADA... | 86 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P08670-86- | FSLADA... | 86 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-87- | SLADAI... | 87 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P08670-87- | SLADAI... | 87 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P08670-87- | SLADAI... | 87 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
P08670-87- | SLADAI... | 87 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-87- | SLADAI... | 87 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P08670-87- | SLADAI... | 87 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
P08670-87- | SLADAI... | 87 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-87-unknown | SLADAI... | 87 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-87-unknown | SLADAI... | 87 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-88- | LADAIN... | 88 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-88- | LADAIN... | 88 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P08670-91-unknown | AINTEF... | 91 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11128 | |||
P08670-91-unknown | AINTEF... | 91 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-91-unknown | AINTEF... | 91 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-91- | AINTEF... | 91 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P08670-91- | AINTEF... | 91 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P08670-91- | AINTEF... | 91 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-91- | AINTEF... | 91 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P08670-91- | AINTEF... | 91 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
P08670-91- | AINTEF... | 91 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P08670-91- | AINTEF... | 91 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-133-unknown | AELEQL... | 133 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17229 | |||
P08670-133-unknown | AELEQL... | 133 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18600 | |||
P08670-177-unknown | NLAEDI... | 177 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11129 | |||
P08670-205- | SFRQDV... | 205 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-226-unknown | SLQEEI... | 226 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17230 | |||
P08670-227-unknown | LQEEIA... | 227 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17231 | |||
P08670-230-unknown | EIAFLK... | 230 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17232 | |||
P08670-247-unknown | AQIQEQ... | 247 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7256 | |||
P08670-258-unknown | VDVSKP... | 258 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11130 | |||
P08670-258-unknown | VDVSKP... | 258 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18601 | |||
P08670-258-unknown | VDVSKP... | 258 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-258-unknown | VDVSKP... | 258 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-258- | VDVSKP... | 258 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P08670-258- | VDVSKP... | 258 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P08670-258- | VDVSKP... | 258 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
P08670-258- | VDVSKP... | 258 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P08670-258- | VDVSKP... | 258 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-258- | VDVSKP... | 258 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P08670-258- | VDVSKP... | 258 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P08670-258- | VDVSKP... | 258 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
P08670-258- | VDVSKP... | 258 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-259-unknown | DVSKPD... | 259 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18602 | |||
P08670-260-unknown | VSKPDL... | 260 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1130 | |||
P08670-260-unknown | VSKPDL... | 260 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3184 | |||
P08670-260-unknown | VSKPDL... | 260 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11131 | |||
P08670-260-unknown | VSKPDL... | 260 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2475 | |||
P08670-260-unknown | VSKPDL... | 260 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3030 | |||
P08670-260-unknown | VSKPDL... | 260 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-260-unknown | VSKPDL... | 260 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | RMPI_untreated | 23264352 | |||
P08670-260- | VSKPDL... | 260 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-261- | SKPDLT... | 261 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P08670-332-unknown | ALKGTN... | 332 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11132 | |||
P08670-332-unknown | ALKGTN... | 332 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P08670-332- | ALKGTN... | 332 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P08670-332- | ALKGTN... | 332 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P08670-332- | ALKGTN... | 332 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
P08670-332- | ALKGTN... | 332 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-332- | ALKGTN... | 332 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P08670-332- | ALKGTN... | 332 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-429-unknown | DSLPLV... | 429 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18603 | |||
P08670-430- | SLPLVD... | 430 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P08670-430- | SLPLVD... | 430 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P08670-430- | SLPLVD... | 430 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P08670-431-unknown | LPLVDT... | 431 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18604 | |||
P08670-434-unknown | VDTHSK... | 434 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17233 | |||
P08670-441-unknown | TLLIKT... | 441 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...TTSTRT | 36 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9954 | |||
...RTYSLG | 40 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15319 | |||
...TYSLGS | 41 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7255 | |||
...QDSVDF | 85 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1613 | |||
...QDSVDF | 85 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2800 | |||
...FSLADA | 90 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11128 | |||
...NKILLA | 132 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17229 | |||
...NKILLA | 132 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18600 | |||
...EVERDN | 176 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11129 | |||
...ERKVES | 225 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17230 | |||
...RKVESL | 226 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17231 | |||
...ESLQEE | 229 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17232 | |||
...IQELQA | 246 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7256 | |||
...HVQIDV | 257 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11130 | |||
...HVQIDV | 257 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18601 | |||
...VQIDVD | 258 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18602 | |||
...QIDVDV | 259 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1130 | |||
...QIDVDV | 259 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3184 | |||
...QIDVDV | 259 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11131 | |||
...QIDVDV | 259 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2475 | |||
...QIDVDV | 259 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3030 | |||
...TCEVDA | 331 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11132 | |||
...RETNLD | 428 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18603 | |||
...TNLDSL | 430 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18604 | |||
...DSLPLV | 433 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17233 | |||
...HDDLE | 466 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|