P07900: Heat shock protein HSP 90-alpha

General Information

Protein names	- Heat shock protein HSP 90-alpha - Heat shock 86 kDa - HSP 86 - HSP86 - Lipopolysaccharide-associated protein 2 - LAP-2 - LPS-associated protein 2 - Renal carcinoma antigen NY-REN-38
Gene names	HSP90AA1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P07900

57 N-termini

27 C-termini

36 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPEETQTQDQ PMEEEEVETF AFQAEIAQLM SLIINTFYSN KEIFLRELIS NSSDALDKIR
        70         80         90        100        110        120
YESLTDPSKL DSGKELHINL IPNKQDRTLT IVDTGIGMTK ADLINNLGTI AKSGTKAFME
       130        140        150        160        170        180
ALQAGADISM IGQFGVGFYS AYLVAEKVTV ITKHNDDEQY AWESSAGGSF TVRTDTGEPM
       190        200        210        220        230        240
GRGTKVILHL KEDQTEYLEE RRIKEIVKKH SQFIGYPITL FVEKERDKEV SDDEAEEKED
       250        260        270        280        290        300
KEEEKEKEEK ESEDKPEIED VGSDEEEEKK DGDKKKKKKI KEKYIDQEEL NKTKPIWTRN
       310        320        330        340        350        360
PDDITNEEYG EFYKSLTNDW EDHLAVKHFS VEGQLEFRAL LFVPRRAPFD LFENRKKKNN
       370        380        390        400        410        420
IKLYVRRVFI MDNCEELIPE YLNFIRGVVD SEDLPLNISR EMLQQSKILK VIRKNLVKKC
       430        440        450        460        470        480
LELFTELAED KENYKKFYEQ FSKNIKLGIH EDSQNRKKLS ELLRYYTSAS GDEMVSLKDY
       490        500        510        520        530        540
CTRMKENQKH IYYITGETKD QVANSAFVER LRKHGLEVIY MIEPIDEYCV QQLKEFEGKT
       550        560        570        580        590        600
LVSVTKEGLE LPEDEEEKKK QEEKKTKFEN LCKIMKDILE KKVEKVVVSN RLVTSPCCIV
       610        620        630        640        650        660
TSTYGWTANM ERIMKAQALR DNSTMGYMAA KKHLEINPDH SIIETLRQKA EADKNDKSVK
       670        680        690        700        710        720
DLVILLYETA LLSSGFSLED PQTHANRIYR MIKLGLGIDE DDPTADDTSA AVTEEMPPLE
       730
GDDDTSRMEE VD

Isoforms

- Isoform 2 of Heat shock protein HSP 90-alpha

Sequence View

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Protein Neighborhood

Domains & Features

57 N-termini - 27 C-termini - 36 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P07900-2-unknown	PEETQT...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P07900-2-unknown	PEETQT...	2		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111311
P07900-9-unknown	DQPMEE...	9		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P07900-9-unknown	DQPMEE...	9		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194832
P07900-51-unknown	NSSDAL...	51		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5453
P07900-51-unknown	NSSDAL...	51		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145625
P07900-52-	SSDALD...	52			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P07900-52-	SSDALD...	52			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P07900-52-unknown	SSDALD...	52		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166242
P07900-78-unknown	INLIPN...	78		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17184
P07900-78-unknown	INLIPN...	78		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146561
P07900-91-unknown	IVDTGI...	91		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7224
P07900-91-unknown	IVDTGI...	91		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5455
P07900-91-unknown	IVDTGI...	91		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147102
P07900-164-unknown	SSAGGS...	164		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5457
P07900-164-unknown	SSAGGS...	164		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149487
P07900-164-	SSAGGS...	164			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07900-165-unknown	SAGGSF...	165		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170674
P07900-165-	SAGGSF...	165			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07900-176-unknown	TGEPMG...	176		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11101
P07900-176-unknown	TGEPMG...	176		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2461
P07900-176-unknown	TGEPMG...	176		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149813
P07900-177-unknown	GEPMGR...	177		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P07900-177-unknown	GEPMGR...	177		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197862
P07900-189-unknown	HLKEDQ...	189		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5459
P07900-189-unknown	HLKEDQ...	189		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150136
P07900-190-unknown	LKEDQT...	190		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7226
P07900-190-unknown	LKEDQT...	190		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150152
P07900-215-	GYPITL...	215			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07900-215-unknown	GYPITL...	215		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173145
P07900-216-unknown	YPITLF...	216		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17186
P07900-216-unknown	YPITLF...	216		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150672
P07900-228-unknown	KEVSDD...	228		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2463
P07900-228-unknown	KEVSDD...	228		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150943
P07900-234-unknown	EAEEKE...	234		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2465
P07900-234-unknown	EAEEKE...	234		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151080
P07900-265-unknown	EEEEKK...	265		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2467
P07900-265-unknown	EEEEKK...	265		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151780
P07900-282-	EKYIDQ...	282			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P07900-282-unknown	EKYIDQ...	282		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169883
P07900-284-	YIDQEE...	284			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P07900-284-unknown	YIDQEE...	284		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169885
P07900-300-acetylation	NPDDIT...	300	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P07900-300-acetylation	NPDDIT...	300	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt181466
P07900-315-unknown	SLTNDW...	315		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170671
P07900-315-	SLTNDW...	315			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07900-315-	SLTNDW...	315			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P07900-318-unknown	NDWEDH...	318		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7228
P07900-318-unknown	NDWEDH...	318		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5461
P07900-318-unknown	NDWEDH...	318		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152634
P07900-330-unknown	SVEGQL...	330		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170676
P07900-330-	SVEGQL...	330			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07900-387-unknown	GVVDSE...	387		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt181468
P07900-387-	GVVDSE...	387			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P07900-425-unknown	TELAED...	425		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17188
P07900-425-unknown	TELAED...	425		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5463
P07900-425-unknown	TELAED...	425		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153956
P07900-426-unknown	ELAEDK...	426		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7230
P07900-426-unknown	ELAEDK...	426		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153966
P07900-468-unknown	SASGDE...	468		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7232
P07900-468-unknown	SASGDE...	468		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5465
P07900-468-unknown	SASGDE...	468		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt154459
P07900-492-unknown	YYITGE...	492			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P07900-492-unknown	YYITGE...	492		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161679
P07900-500-acetylation	DQVANS...	500	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P07900-500-acetylation	DQVANS...	500	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt181470
P07900-551-unknown	LPEDEE...	551		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7234
P07900-551-unknown	LPEDEE...	551		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155579
P07900-577-unknown	DILEKK...	577		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17190
P07900-577-unknown	DILEKK...	577		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18563
P07900-577-unknown	DILEKK...	577		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155847
P07900-613-unknown	IMKAQA...	613		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13932
P07900-613-unknown	IMKAQA...	613		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156168
P07900-618-unknown	ALRDNS...	618			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P07900-618-unknown	ALRDNS...	618		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt159751
P07900-618-	ALRDNS...	618			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P07900-623-unknown	STMGYM...	623		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166240
P07900-623-	STMGYM...	623			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P07900-623-	STMGYM...	623			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07900-632-unknown	KHLEIN...	632		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173147
P07900-632-	KHLEIN...	632			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07900-634-unknown	LEINPD...	634		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17192
P07900-634-unknown	LEINPD...	634		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156290
P07900-635-	EINPDH...	635			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P07900-635-	EINPDH...	635			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P07900-635-unknown	EINPDH...	635			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P07900-635-unknown	EINPDH...	635		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161677
P07900-639-unknown	DHSIIE...	639		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17194
P07900-639-unknown	DHSIIE...	639		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156315
P07900-640-unknown	HSIIET...	640		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17196
P07900-640-unknown	HSIIET...	640		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11103
P07900-640-unknown	HSIIET...	640		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156319
P07900-671-unknown	LLSSGF...	671		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19950
P07900-671-unknown	LLSSGF...	671		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156469
P07900-678-unknown	LEDPQT...	678		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7236
P07900-678-unknown	LEDPQT...	678		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5467
P07900-678-unknown	LEDPQT...	678		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156482
P07900-702-unknown	DPTADD...	702		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11105
P07900-702-unknown	DPTADD...	702		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2469
P07900-702-unknown	DPTADD...	702		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156580
P07900-703-unknown	PTADDT...	703		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2471
P07900-703-unknown	PTADDT...	703		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156584
P07900-723-unknown	DDTSRM...	723		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11107
P07900-723-unknown	DDTSRM...	723		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2473
P07900-723-unknown	DDTSRM...	723		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156672

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RELISN	50	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5453
...RELISN	50	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128924
...GKELHI	77	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17184
...GKELHI	77	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129867
...DRTLTI	90	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7224
...DRTLTI	90	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5455
...DRTLTI	90	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130436
...QYAWES	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5457
...QYAWES	163	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132871
...TVRTDT	175	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11101
...TVRTDT	175	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2461
...TVRTDT	175	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133205
...TKVILH	188	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5459
...TKVILH	188	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133528
...KVILHL	189	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7226
...KVILHL	189	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133545
...SQFIGY	215	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17186
...SQFIGY	215	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134070
...EKERDK	227	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2463
...EKERDK	227	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134345
...EVSDDE	233	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2465
...EVSDDE	233	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134483
...DVGSDE	264	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2467
...DVGSDE	264	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135184
...YKSLTN	317	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7228
...YKSLTN	317	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5461
...YKSLTN	317	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136051
...CLELFT	424	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17188
...CLELFT	424	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5463
...CLELFT	424	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137378
...LELFTE	425	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7230
...LELFTE	425	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137388
...LRYYTS	467	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7232
...LRYYTS	467	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5465
...LRYYTS	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137880
...KEGLEL	550	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7234
...KEGLEL	550	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139019
...CKIMKD	576	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17190
...CKIMKD	576	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18563
...CKIMKD	576	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139300
...ANMERI	612	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13932
...ANMERI	612	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139634
...AAKKHL	633	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17192
...AAKKHL	633	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139762
...LEINPD	638	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17194
...LEINPD	638	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139787
...EINPDH	639	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17196
...EINPDH	639	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11103
...EINPDH	639	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139791
...LYETAL	670	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19950
...LYETAL	670	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139951
...SSGFSL	677	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7236
...SSGFSL	677	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5467
...SSGFSL	677	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139964
...GIDEDD	701	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11105
...GIDEDD	701	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2469
...GIDEDD	701	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140065
...IDEDDP	702	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2471
...IDEDDP	702	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140069
...PLEGDD	722	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11107
...PLEGDD	722	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2473
...PLEGDD	722	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140158
...MEEVD	732	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...MEEVD	732	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72902

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	50	LISN.\|.NSSD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	77	ELHI.\|.INLI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATS_HUMAN	90	TLTI.\|.IVDT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	90	TLTI.\|.IVDT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	163	AWES.\|.SSAG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	175	RTDT.\|.TGEP	inferred from experiment	unknown	MEROPS	Craik CS	Hostetter DR et al.:Hip is a pro-survival substrate... (S01.010)	17620340,
CASP6_HUMAN	175	RTDT.\|.TGEP	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CATL1_HUMAN	188	VILH.\|.HLKE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	189	ILHL.\|.LKED	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	215	FIGY.\|.YPIT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CASP6_HUMAN	227	ERDK.\|.KEVS	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CASP6_HUMAN	233	SDDE.\|.EAEE	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CASP6_HUMAN	264	GSDE.\|.EEEE	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CATS_HUMAN	317	SLTN.\|.NDWE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	317	SLTN.\|.NDWE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	424	ELFT.\|.TELA	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	424	ELFT.\|.TELA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	425	LFTE.\|.ELAE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	467	YYTS.\|.SASG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	467	YYTS.\|.SASG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	550	GLEL.\|.LPED	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	576	IMKD.\|.DILE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	576	IMKD.\|.DILE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAM_HUMAN	612	MERI.\|.IMKA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
MEP1A_HUMAN	633	KKHL.\|.LEIN	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	638	INPD.\|.DHSI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	639	NPDH.\|.HSII	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	639	NPDH.\|.HSII	inferred from experiment	unknown	MEROPS	Craik CS	Hostetter DR et al.:Hip is a pro-survival substrate... (S01.010)	17620340,
MMP11_HUMAN	670	ETAL.\|.LLSS	inferred from experiment	unknown	MEROPS		Merops MMP11_HUMAN -> HS90A_HUMAN @670
CATS_HUMAN	677	GFSL.\|.LEDP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	677	GFSL.\|.LEDP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	701	DEDD.\|.DPTA	inferred from experiment	unknown	MEROPS	Craik CS	Hostetter DR et al.:Hip is a pro-survival substrate... (S01.010)	17620340,
CASP6_HUMAN	701	DEDD.\|.DPTA	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CASP6_HUMAN	702	EDDP.\|.PTAD	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
GRAB_HUMAN	722	EGDD.\|.DDTS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CASP6_HUMAN	722	EGDD.\|.DDTS	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)