Q13748: Tubulin alpha-3C/D chain

General Information

Protein names	- Tubulin alpha-3C/D chain - Alpha-tubulin 2 - Alpha-tubulin 3C/D - Tubulin alpha-2 chain
Gene names	TUBA3D
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location	q12.11
UniProt ID	Q13748

28 N-termini

29 C-termini

29 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK
        70         80         90        100        110        120
HVPRAVFVDL EPTVVDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIVDLVLD
       130        140        150        160        170        180
RIRKLADLCT GLQGFLIFHS FGGGTGSGFA SLLMERLSVD YGKKSKLEFA IYPAPQVSTA
       190        200        210        220        230        240
VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL IGQIVSSITA
       250        260        270        280        290        300
SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN
       310        320        330        340        350        360
QMVKCDPRHG KYMACCMLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP
       370        380        390        400        410        420
TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE
       430        440        450
AREDLAALEK DYEEVGVDSV EAEAEEGEEY

Isoforms

- Isoform 2 of Tubulin alpha-3C/D chain

Sequence View

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q13748-1-unknown	MRECIS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q13748-1-unknown	MRECIS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91579
Q13748-34-unknown	GQMPSD...	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2707
Q13748-34-unknown	GQMPSD...	34	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137899
Q13748-41-unknown	TIGGGD...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10268
Q13748-41-unknown	TIGGGD...	41	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138397
Q13748-57-unknown	GAGKHV...	57	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15408
Q13748-57-unknown	GAGKHV...	57	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139664
Q13748-70-unknown	LEPTVV...	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2709
Q13748-70-unknown	LEPTVV...	70	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140655
Q13748-85-unknown	QLFHPE...	85	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10270
Q13748-85-unknown	QLFHPE...	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141549
Q13748-91-unknown	QLITGK...	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12100
Q13748-91-unknown	QLITGK...	91	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141871
Q13748-93-unknown	ITGKED...	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15410
Q13748-93-unknown	ITGKED...	93	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141988
Q13748-201-unknown	AFMVDN...	201	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15412
Q13748-201-unknown	AFMVDN...	201	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14457
Q13748-201-unknown	AFMVDN...	201	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146594
Q13748-205-unknown	DNEAIY...	205	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15414
Q13748-205-unknown	DNEAIY...	205	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146706
Q13748-206-unknown	NEAIYD...	206	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12102
Q13748-206-unknown	NEAIYD...	206	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146751
Q13748-208-unknown	AIYDIC...	208	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12104
Q13748-208-unknown	AIYDIC...	208	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146840
Q13748-252-unknown	LTEFQT...	252	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12106
Q13748-252-unknown	LTEFQT...	252	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt148484
Q13748-254-unknown	EFQTNL...	254	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15416
Q13748-254-unknown	EFQTNL...	254	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt148582
Q13748-270-unknown	ATYAPV...	270	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14459
Q13748-270-unknown	ATYAPV...	270	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149120
Q13748-287-unknown	SVAEIT...	287	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14461
Q13748-287-unknown	SVAEIT...	287	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149514
Q13748-292-unknown	TNACFE...	292	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15418
Q13748-292-unknown	TNACFE...	292	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149631
Q13748-307-unknown	PRHGKY...	307	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2711
Q13748-307-unknown	PRHGKY...	307	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150057
Q13748-328-unknown	VNAAIA...	328	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2713
Q13748-328-unknown	VNAAIA...	328	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150487
Q13748-329-unknown	NAAIAT...	329	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15420
Q13748-329-unknown	NAAIAT...	329	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150503
Q13748-353-unknown	VGINYQ...	353	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10272
Q13748-353-unknown	VGINYQ...	353	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151001
Q13748-354-unknown	GINYQP...	354	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15422
Q13748-354-unknown	GINYQP...	354	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151030
Q13748-356-unknown	NYQPPT...	356	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14463
Q13748-356-unknown	NYQPPT...	356	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151077
Q13748-368-unknown	LAKVQR...	368	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12108
Q13748-368-unknown	LAKVQR...	368	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151372
Q13748-408-unknown	YVGEGM...	408	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15424
Q13748-414-unknown	EEGEFS...	414	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15425
Q13748-432-unknown	YEEVGV...	432	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2715
Q13748-432-unknown	YEEVGV...	432	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199466
Q13748-439-unknown	SVEAEA...	439	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2716
Q13748-439-unknown	SVEAEA...	439	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152114

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GIQPDG	33	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2707
...GIQPDG	33	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120906
...MPSDKT	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10268
...MPSDKT	40	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121438
...FFSETG	56	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15408
...FFSETG	56	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122759
...AVFVDL	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2709
...AVFVDL	69	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123790
...TGTYRQ	84	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10270
...TGTYRQ	84	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124726
...LFHPEQ	90	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12100
...LFHPEQ	90	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125049
...HPEQLI	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15410
...HPEQLI	92	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125169
...EHSDCA	200	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15412
...EHSDCA	200	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14457
...EHSDCA	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129901
...CAFMVD	204	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15414
...CAFMVD	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130016
...AFMVDN	205	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12102
...AFMVDN	205	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130062
...MVDNEA	207	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12104
...MVDNEA	207	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130166
...ALNVDL	251	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12106
...ALNVDL	251	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131857
...NVDLTE	253	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15416
...NVDLTE	253	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131956
...IHFPLA	269	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14459
...IHFPLA	269	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132505
...YHEQLS	286	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14461
...YHEQLS	286	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132899
...SVAEIT	291	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15418
...SVAEIT	291	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133018
...MVKCDP	306	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2711
...MVKCDP	306	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133449
...VVPKDV	327	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2713
...VVPKDV	327	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133883
...VPKDVN	328	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15420
...VPKDVN	328	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133899
...PTGFKV	352	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10272
...PTGFKV	352	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134404
...TGFKVG	353	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15422
...TGFKVG	353	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134434
...FKVGIN	355	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14463
...FKVGIN	355	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134480
...VPGGDL	367	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12108
...VPGGDL	367	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134774
...AFVHWY	407	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15424
...VGEGME	413	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15425
...ALEKDY	431	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2715
...EVGVDS	438	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2716
...EEGEEY	449	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8290
...EEGEEY	449	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135711
...EGEEY	450	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EGEEY	450	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87197

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP6_HUMAN	33	QPDG.\|.GQMP	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
GRAA_HUMAN	40	SDKT.\|.TIGG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
HTRA2_HUMAN	56	SETG.\|.GAGK	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
CASP6_HUMAN	69	FVDL.\|.LEPT	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
GRAA_HUMAN	84	TYRQ.\|.QLFH	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	90	HPEQ.\|.QLIT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
HTRA2_HUMAN	92	EQLI.\|.ITGK	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
HTRA2_HUMAN	200	SDCA.\|.AFMV	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAM_HUMAN	200	SDCA.\|.AFMV	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
HTRA2_HUMAN	204	FMVD.\|.DNEA	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAB_HUMAN	205	MVDN.\|.NEAI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	207	DNEA.\|.AIYD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	251	NVDL.\|.LTEF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
HTRA2_HUMAN	253	DLTE.\|.EFQT	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAM_HUMAN	269	FPLA.\|.ATYA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	286	EQLS.\|.SVAE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
HTRA2_HUMAN	291	AEIT.\|.TNAC	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
CASP6_HUMAN	306	KCDP.\|.PRHG	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CASP6_HUMAN	327	PKDV.\|.VNAA	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
HTRA2_HUMAN	328	KDVN.\|.NAAI	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAA_HUMAN	352	GFKV.\|.VGIN	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
HTRA2_HUMAN	353	FKVG.\|.GINY	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAM_HUMAN	355	VGIN.\|.NYQP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	367	GGDL.\|.LAKV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
HTRA2_HUMAN	407	VHWY.\|.YVGE	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
HTRA2_HUMAN	413	EGME.\|.EEGE	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
CASP6_HUMAN	431	EKDY.\|.YEEV	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CASP6_HUMAN	438	GVDS.\|.SVEA	inferred from experiment	unknown	MEROPS	Leblanc AC	Klaiman G et al.:Targets of caspase-6 activity i... (C14.005)	18487604,
CBPC1_HUMAN	449	GEEY.\|.Y	inferred from experiment	unknown	MEROPS		Merops CBPC1_HUMAN -> TBA3C_HUMAN @449

TopFIND

Q13748: Tubulin alpha-3C/D chain

General Information

28

N-termini

29

C-termini

29

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

28 N-termini - 29 C-termini - 29 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates