Q07020: 60S ribosomal protein L18

General Information

Protein names	- 60S ribosomal protein L18 - Large ribosomal subunit protein eL18 {ECO:0000303\|PubMed:24524803}
Gene names	RPL18
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q07020

11 N-termini

9 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGVDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN STFNQVVLKR LFMSRTNRPP
        70         80         90        100        110        120
LSLSRMIRKM KLPGRENKTA VVVGTITDDV RVQEVPKLKV CALRVTSRAR SRILRAGGKI
       130        140        150        160        170        180
LTFDQLALDS PKGCGTVLLS GPRKGREVYR HFGKAPGTPH SHTKPYVRSK GRKFERARGR

RASRGYKN

Isoforms

- Isoform 2 of 60S ribosomal protein L18

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

11 N-termini - 9 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q07020-2-	GVDIRH...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q07020-2-	GVDIRH...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07020-2-	GVDIRH...	2		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q07020-2-unknown	GVDIRH...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q07020-53-unknown	MSRTNR...	53	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000447894
Q07020-79-unknown	TAVVVG...	79	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10212
Q07020-79-	TAVVVG...	79		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q07020-84-	GTITDD...	84		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07020-104-unknown	RVTSRA...	104	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14377
Q07020-123-unknown	FDQLAL...	123	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6242
Q07020-125-unknown	QLALDS...	125	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11931
Q07020-127-unknown	ALDSPK...	127	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14378
Q07020-129-unknown	DSPKGC...	129	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14379

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GRENKT	78	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10212
...KVCALR	103	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14377
...GKILTF	122	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6242
...ILTFDQ	124	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11931
...TFDQLA	126	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14378
...DQLALD	128	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14379
...HSHTKP	164	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000449610
...RGRRAS	182	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447894
...RGYKN	188	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	78	ENKT.\|.TAVV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	103	CALR.\|.RVTS	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATL1_HUMAN	122	ILTF.\|.FDQL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	124	TFDQ.\|.QLAL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAM_HUMAN	126	DQLA.\|.ALDS	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	128	LALD.\|.DSPK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)