TopFIND 4.0

P26599: Polypyrimidine tract-binding protein 1

General Information

Protein names
- Polypyrimidine tract-binding protein 1
- PTB
- 57 kDa RNA-binding protein PPTB-1
- Heterogeneous nuclear ribonucleoprotein I
- hnRNP I

Gene names PTBP1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P26599

52

N-termini

18

C-termini

23

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDGIVPDIAV GTKRGSDELF STCVTNGPFI MSSNSASAAN GNDSKKFKGD SRSAGVPSRV 
        70         80         90        100        110        120 
IHIRKLPIDV TEGEVISLGL PFGKVTNLLM LKGKNQAFIE MNTEEAANTM VNYYTSVTPV 
       130        140        150        160        170        180 
LRGQPIYIQF SNHKELKTDS SPNQARAQAA LQAVNSVQSG NLALAASAAA VDAGMAMAGQ 
       190        200        210        220        230        240 
SPVLRIIVEN LFYPVTLDVL HQIFSKFGTV LKIITFTKNN QFQALLQYAD PVSAQHAKLS 
       250        260        270        280        290        300 
LDGQNIYNAC CTLRIDFSKL TSLNVKYNND KSRDYTRPDL PSGDSQPSLD QTMAAAFGLS 
       310        320        330        340        350        360 
VPNVHGALAP LAIPSAAAAA AAAGRIAIPG LAGAGNSVLL VSNLNPERVT PQSLFILFGV 
       370        380        390        400        410        420 
YGDVQRVKIL FNKKENALVQ MADGNQAQLA MSHLNGHKLH GKPIRITLSK HQNVQLPREG 
       430        440        450        460        470        480 
QEDQGLTKDY GNSPLHRFKK PGSKNFQNIF PPSATLHLSN IPPSVSEEDL KVLFSSNGGV 
       490        500        510        520        530    
VKGFKFFQKD RKMALIQMGS VEEAVQALID LHNHDLGENH HLRVSFSKST I

Isoforms

- Isoform 2 of Polypyrimidine tract-binding protein 1 - Isoform 3 of Polypyrimidine tract-binding protein 1

Sequence View

        10         20         30         40         50         60 
MDGIVPDIAV GTKRGSDELF STCVTNGPFI MSSNSASAAN GNDSKKFKGD SRSAGVPSRV 
        70         80         90        100        110        120 
IHIRKLPIDV TEGEVISLGL PFGKVTNLLM LKGKNQAFIE MNTEEAANTM VNYYTSVTPV 
       130        140        150        160        170        180 
LRGQPIYIQF SNHKELKTDS SPNQARAQAA LQAVNSVQSG NLALAASAAA VDAGMAMAGQ 
       190        200        210        220        230        240 
SPVLRIIVEN LFYPVTLDVL HQIFSKFGTV LKIITFTKNN QFQALLQYAD PVSAQHAKLS 
       250        260        270        280        290        300 
LDGQNIYNAC CTLRIDFSKL TSLNVKYNND KSRDYTRPDL PSGDSQPSLD QTMAAAFGLS 
       310        320        330        340        350        360 
VPNVHGALAP LAIPSAAAAA AAAGRIAIPG LAGAGNSVLL VSNLNPERVT PQSLFILFGV 
       370        380        390        400        410        420 
YGDVQRVKIL FNKKENALVQ MADGNQAQLA MSHLNGHKLH GKPIRITLSK HQNVQLPREG 
       430        440        450        460        470        480 
QEDQGLTKDY GNSPLHRFKK PGSKNFQNIF PPSATLHLSN IPPSVSEEDL KVLFSSNGGV 
       490        500        510        520        530    
VKGFKFFQKD RKMALIQMGS VEEAVQALID LHNHDLGENH HLRVSFSKST I         10         20         30         40         50         60 
MDGIVPDIAV GTKRGSDELF STCVTNGPFI MSSNSASAAN GNDSKKFKGD SRSAGVPSRV 
        70         80         90        100        110        120 
IHIRKLPIDV TEGEVISLGL PFGKVTNLLM LKGKNQAFIE MNTEEAANTM VNYYTSVTPV 
       130        140        150        160        170        180 
LRGQPIYIQF SNHKELKTDS SPNQARAQAA LQAVNSVQSG NLALAASAAA VDAGMAMAGQ 
       190        200        210        220        230        240 
SPVLRIIVEN LFYPVTLDVL HQIFSKFGTV LKIITFTKNN QFQALLQYAD PVSAQHAKLS 
       250        260        270        280        290        300 
LDGQNIYNAC CTLRIDFSKL TSLNVKYNND KSRDYTRPDL PSGDSQPSLD QTMAAAFGLS 
       310        320        330        340        350        360 
VPNVHGALAP LAIPSAAAAA AAAGRIAIPG LAGAGNSVLL VSNLNPERVT PQSLFILFGV 
       370        380        390        400        410        420 
YGDVQRVKIL FNKKENALVQ MADGNQAQLA MSHLNGHKLH GKPIRITLSK HQNVQLPREG 
       430        440        450        460        470        480 
QEDQGLTKDY GNSPLHRFKK PGSKNFQNIF PPSATLHLSN IPPSVSEEDL KVLFSSNGGV 
       490        500        510        520        530    
VKGFKFFQKD RKMALIQMGS VEEAVQALID LHNHDLGENH HLRVSFSKST I



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

52 N-termini - 18 C-termini - 23 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)