P20645: Cation-dependent mannose-6-phosphate receptor

General Information

Protein names	- Cation-dependent mannose-6-phosphate receptor - CD Man-6-P receptor - CD-MPR - 46 kDa mannose 6-phosphate receptor - MPR 46
Gene names	M6PR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P20645

5 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MFPFYSCWRT GLLLLLLAVA VRESWQTEEK TCDLVGEKGK ESEKELALVK RLKPLFNKSF
        70         80         90        100        110        120
ESTVGQGSDT YIYIFRVCRE AGNHTSGAGL VQINKSNGKE TVVGRLNETH IFNGSNWIML
       130        140        150        160        170        180
IYKGGDEYDN HCGKEQRRAV VMISCNRHTL ADNFNPVSEE RGKVQDCFYL FEMDSSLACS
       190        200        210        220        230        240
PEISHLSVGS ILLVTFASLV AVYVVGGFLY QRLVVGAKGM EQFPHLAFWQ DLGNLVADGC
       250        260        270
DFVCRSKPRN VPAAYRGVGD DQLGEESEER DDHLLPM

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P20645-13-unknown	LLLLLA...	13	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437595
P20645-27-unknown	TEEKTC...	27	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P20645-119-unknown	MLIYKG...	119	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000439968
P20645-204-unknown	VVGGFL...	204	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000441040
P20645-257-unknown	GVGDDQ...	257	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10025

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AGLVQI	92	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000441030
...RLNETH	109	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440962
...AVVMIS	143	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000439968
...PAAYRG	256	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10025
...HLLPM	277	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	256	AYRG.\|.GVGD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)