P04908: Histone H2A type 1-B/E
Protein names | - Histone H2A type 1-B/E - Histone H2A.2 - Histone H2A/a - Histone H2A/m |
---|---|
Gene names | HIST1H2AE |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P04908 |
9
N-termini
5
C-termini
5
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY SERVGAGAPV YLAAVLEYLT
70 80 90 100 110 120
AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGR VTIAQGGVLP NIQAVLLPKK
130
TESHHKAKGK
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
9 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P04908-2-unknown | MSGRGK... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P04908-2-Acetylation | SGRGKQ... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P04908-22-unknown | AGLQFP... | 22 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9931 | |||
P04908-60-unknown | TAEILE... | 60 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13914 | |||
P04908-60-unknown | TAEILE... | 60 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9932 | |||
P04908-61-unknown | AEILEL... | 61 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9933 | |||
P04908-83-unknown | HLQLAI... | 83 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9934 | |||
P04908-85- | QLAIRN... | 85 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P04908-106- | GGVLPN... | 106 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P04908-107- | GVLPNI... | 107 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...TRSSRA | 21 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9931 | |||
...VLEYLT | 59 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13914 | |||
...VLEYLT | 59 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9932 | |||
...LEYLTA | 60 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9933 | |||
...RIIPRH | 82 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9934 | |||
...KAKGK | 130 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAA_HUMAN | 21 | SSRA.|.AGLQ | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:The substrate specificity profi... (S01.135) | 20536382, |
GRAM_HUMAN | 59 | EYLT.|.TAEI | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
GRAA_HUMAN | 59 | EYLT.|.TAEI | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:The substrate specificity profi... (S01.135) | 20536382, |
GRAA_HUMAN | 60 | YLTA.|.AEIL | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:The substrate specificity profi... (S01.135) | 20536382, |
GRAA_HUMAN | 82 | IPRH.|.HLQL | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:The substrate specificity profi... (S01.135) | 20536382, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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