Q02543: 60S ribosomal protein L18a

General Information

Protein names	- 60S ribosomal protein L18a - Large ribosomal subunit protein eL20 {ECO:0000303\|PubMed:24524803}
Gene names	RPL18A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q02543

9 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKASGTLREY KVVGRCLPTP KCHTPPLYRM RIFAPNHVVA KSRFWYFVSQ LKKMKKSSGE
        70         80         90        100        110        120
IVYCGQVFEK SPLRVKNFGI WLRYDSRSGT HNMYREYRDL TTAGAVTQCY RDMGARHRAR
       130        140        150        160        170
AHSIQIMKVE EIAASKCRRP AVKQFHDSKI KFPLPHRVLR RQHKPRFTTK RPNTFF

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q02543-1-	MKASGT...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q02543-1-	MKASGT...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q02543-1-	MKASGT...	1		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q02543-1-unknown	MKASGT...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q02543-1-unknown	MKASGT...	1		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q02543-1-unknown	MKASGT...	1		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q02543-16-unknown	CLPTPK...	16	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10190
Q02543-30-unknown	MRIFAP...	30	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000473155
Q02543-30-unknown	MRIFAP...	30	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000471748
Q02543-32-	IFAPNH...	32		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q02543-34-unknown	FAPNHV...	33	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q02543-34-unknown	FAPNHV...	33	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6221
Q02543-45-	WYFVSQ...	45		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q02543-121-	AHSIQI...	121		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q02543-123-	SIQIMK...	123		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KVVGRC	15	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10190
...RMRIFA	33	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6221
...RFTTKR	170	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473155
...PNTFF	176	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	15	VGRC.\|.CLPT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CATL1_HUMAN	33	RIFA.\|.APNH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)