P49750: YLP motif-containing protein 1
Protein names | - YLP motif-containing protein 1 - Nuclear protein ZAP3 - ZAP113 |
---|---|
Gene names | YLPM1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P49750 |
16
N-termini
4
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MYPNWGRYGG SSHYPPPPVP PPPPVALPEA SPGPGYSSST TPAAPSSSGF MSFREQHLAQ
70 80 90 100 110 120
LQQLQQMHQK QMQCVLQPHH LPPPPLPPPP VMPGGGYGDW QPPPPPMPPP PGPALSYQKQ
130 140 150 160 170 180
QQYKHQMLHH QRDGPPGLVP MELESPPESP PVPPGSYMPP SQSYMPPPQP PPSYYPPTSS
190 200 210 220 230 240
QPYLPPAQPS PSQSPPSQSY LAPTPSYSSS SSSSQSYLSH SQSYLPSSQA SPSRPSQGHS
250 260 270 280 290 300
KSQLLAPPPP SAPPGNKTTV QQEPLESGAK NKSTEQQQAA PEPDPSTMTP QEQQQYWYRQ
310 320 330 340 350 360
HLLSLQQRTK VHLPGHKKGP VVAKDTPEPV KEEVTVPATS QVPESPSSEE PPLPPPNEEV
370 380 390 400 410 420
PPPLPPEEPQ SEDPEEDARL KQLQAAAAHW QQHQQHRVGF QYQGIMQKHT QLQQILQQYQ
430 440 450 460 470 480
QIIQPPPHIQ TMSVDMQLRH YEMQQQQFQH LYQEWEREFQ LWEEQLHSYP HKDQLQEYEK
490 500 510 520 530 540
QWKTWQGHMK ATQSYLQEKV NSFQNMKNQY MGNMSMPPPF VPYSQMPPPL PTMPPPVLPP
550 560 570 580 590 600
SLPPPVMPPA LPATVPPPGM PPPVMPPSLP TSVPPPGMPP SLSSAGPPPV LPPPSLSSAG
610 620 630 640 650 660
PPPVLPPPSL SSTAPPPVMP LPPLSSATPP PGIPPPGVPQ GIPPQLTAAP VPPASSSQSS
670 680 690 700 710 720
QVPEKPRPAL LPTPVSFGSA PPTTYHPPLQ SAGPSEQVNS KAPLSKSALP YSSFSSDQGL
730 740 750 760 770 780
GESSAAPSQP ITAVKDMPVR SGGLLPDPPR SSYLESPRGP RFDGPRRFED LGSRCEGPRP
790 800 810 820 830 840
KGPRFEGNRP DGPRPRYEGH PAEGTKSKWG MIPRGPASQF YITPSTSLSP RQSGPQWKGP
850 860 870 880 890 900
KPAFGQQHQQ QPKSQAEPLS GNKEPLADTS SNQQKNFKMQ SAAFSIAADV KDVKAAQSNE
910 920 930 940 950 960
NLSDSQQEPP KSEVSEGPVE PSNWDQNVQS METQIDKAQA VTQPVPLANK PVPAQSTFPS
970 980 990 1000 1010 1020
KTGGMEGGTA VATSSLTADN DFKPVGIGLP HSENNQDKGL PRPDNRDNRL EGNRGNSSSY
1030 1040 1050 1060 1070 1080
RGPGQSRMED TRDKGLVNRG RGQAISRGPG LVKQEDFRDK MMGRREDSRE KMNRGEGSRD
1090 1100 1110 1120 1130 1140
RGLVRPGSSR EKVPGGLQGS QDRGAAGSRE RGPPRRAGSQ ERGPLRRAGS RERIPPRRAG
1150 1160 1170 1180 1190 1200
SRERGPPRGP GSRERGLGRS DFGRDRGPFR PEPGDGGEKM YPYHRDEPPR APWNHGEERG
1210 1220 1230 1240 1250 1260
HEEFPLDGRN APMERERLDD WDRERYWREC ERDYQDDTLE LYNREDRFSA PPSRSHDGDR
1270 1280 1290 1300 1310 1320
RGPWWDDWER DQDMDEDYNR EMERDMDRDV DRISRPMDMY DRSLDNEWDR DYGRPLDEQE
1330 1340 1350 1360 1370 1380
SQFRERDIPS LPPLPPLPPL PPLDRYRDDR WREERNREHG YDRDFRDRGE LRIREYPERG
1390 1400 1410 1420 1430 1440
DTWREKRDYV PDRMDWERER LSDRWYPSDV DRHSPMAEHM PSSHHSSEMM GSDASLDSDQ
1450 1460 1470 1480 1490 1500
GLGGVMVLSQ RQHEIILKAA QELKMLREQK EQLQKMKDFG SEPQMADHLP PQESRLQNTS
1510 1520 1530 1540 1550 1560
SRPGMYPPPG SYRPPPPMGK PPGSIVRPSA PPARSSVPVT RPPVPIPPPP PPPPLPPPPP
1570 1580 1590 1600 1610 1620
VIKPQTSAVE QERWDEDSFY GLWDTNDEQG LNSEFKSETA AIPSAPVLPP PPVHSSIPPP
1630 1640 1650 1660 1670 1680
GPVPMGMPPM SKPPPVQQTV DYGHGRDIST NKVEQIPYGE RITLRPDPLP ERSTFETEHA
1690 1700 1710 1720 1730 1740
GQRDRYDRER DREPYFDRQS NVIADHRDFK RDRETHRDRD RDRGVIDYDR DRFDRERRPR
1750 1760 1770 1780 1790 1800
DDRAQSYRDK KDHSSSRRGG FDRPSYDRKS DRPVYEGPSM FGGERRTYPE ERMPLPAPSL
1810 1820 1830 1840 1850 1860
SHQPPPAPRV EKKPESKNVD DILKPPGRES RPERIVVIMR GLPGSGKTHV AKLIRDKEVE
1870 1880 1890 1900 1910 1920
FGGPAPRVLS LDDYFITEVE KEEKDPDSGK KVKKKVMEYE YEAEMEETYR TSMFKTFKKT
1930 1940 1950 1960 1970 1980
LDDGFFPFII LDAINDRVRH FDQFWSAAKT KGFEVYLAEM SADNQTCGKR NIHGRKLKEI
1990 2000 2010 2020 2030 2040
NKMADHWETA PRHMMRLDIR SLLQDAAIEE VEMEDFDANI EEQKEEKKDA EEEESELGYI
2050 2060 2070 2080 2090 2100
PKSKWEMDTS EAKLDKLDGL RTGTKRKRDW EAIASRMEDY LQLPDDYDTR ASEPGKKRVR
2110 2120 2130 2140
WADLEEKKDA DRKRAIGFVV GQTDWEKITD ESGHLAEKAL NRTKYI
Isoforms
- Isoform 3 of YLP motif-containing protein 1 - Isoform 4 of YLP motif-containing protein 1 - Isoform 1 of YLP motif-containing protein 1Sequence View
10 20 30 40 50 60
MYPNWGRYGG SSHYPPPPVP PPPPVALPEA SPGPGYSSST TPAAPSSSGF MSFREQHLAQ
70 80 90 100 110 120
LQQLQQMHQK QMQCVLQPHH LPPPPLPPPP VMPGGGYGDW QPPPPPMPPP PGPALSYQKQ
130 140 150 160 170 180
QQYKHQMLHH QRDGPPGLVP MELESPPESP PVPPGSYMPP SQSYMPPPQP PPSYYPPTSS
190 200 210 220 230 240
QPYLPPAQPS PSQSPPSQSY LAPTPSYSSS SSSSQSYLSH SQSYLPSSQA SPSRPSQGHS
250 260 270 280 290 300
KSQLLAPPPP SAPPGNKTTV QQEPLESGAK NKSTEQQQAA PEPDPSTMTP QEQQQYWYRQ
310 320 330 340 350 360
HLLSLQQRTK VHLPGHKKGP VVAKDTPEPV KEEVTVPATS QVPESPSSEE PPLPPPNEEV
370 380 390 400 410 420
PPPLPPEEPQ SEDPEEDARL KQLQAAAAHW QQHQQHRVGF QYQGIMQKHT QLQQILQQYQ
430 440 450 460 470 480
QIIQPPPHIQ TMSVDMQLRH YEMQQQQFQH LYQEWEREFQ LWEEQLHSYP HKDQLQEYEK
490 500 510 520 530 540
QWKTWQGHMK ATQSYLQEKV NSFQNMKNQY MGNMSMPPPF VPYSQMPPPL PTMPPPVLPP
550 560 570 580 590 600
SLPPPVMPPA LPATVPPPGM PPPVMPPSLP TSVPPPGMPP SLSSAGPPPV LPPPSLSSAG
610 620 630 640 650 660
PPPVLPPPSL SSTAPPPVMP LPPLSSATPP PGIPPPGVPQ GIPPQLTAAP VPPASSSQSS
670 680 690 700 710 720
QVPEKPRPAL LPTPVSFGSA PPTTYHPPLQ SAGPSEQVNS KAPLSKSALP YSSFSSDQGL
730 740 750 760 770 780
GESSAAPSQP ITAVKDMPVR SGGLLPDPPR SSYLESPRGP RFDGPRRFED LGSRCEGPRP
790 800 810 820 830 840
KGPRFEGNRP DGPRPRYEGH PAEGTKSKWG MIPRGPASQF YITPSTSLSP RQSGPQWKGP
850 860 870 880 890 900
KPAFGQQHQQ QPKSQAEPLS GNKEPLADTS SNQQKNFKMQ SAAFSIAADV KDVKAAQSNE
910 920 930 940 950 960
NLSDSQQEPP KSEVSEGPVE PSNWDQNVQS METQIDKAQA VTQPVPLANK PVPAQSTFPS
970 980 990 1000 1010 1020
KTGGMEGGTA VATSSLTADN DFKPVGIGLP HSENNQDKGL PRPDNRDNRL EGNRGNSSSY
1030 1040 1050 1060 1070 1080
RGPGQSRMED TRDKGLVNRG RGQAISRGPG LVKQEDFRDK MMGRREDSRE KMNRGEGSRD
1090 1100 1110 1120 1130 1140
RGLVRPGSSR EKVPGGLQGS QDRGAAGSRE RGPPRRAGSQ ERGPLRRAGS RERIPPRRAG
1150 1160 1170 1180 1190 1200
SRERGPPRGP GSRERGLGRS DFGRDRGPFR PEPGDGGEKM YPYHRDEPPR APWNHGEERG
1210 1220 1230 1240 1250 1260
HEEFPLDGRN APMERERLDD WDRERYWREC ERDYQDDTLE LYNREDRFSA PPSRSHDGDR
1270 1280 1290 1300 1310 1320
RGPWWDDWER DQDMDEDYNR EMERDMDRDV DRISRPMDMY DRSLDNEWDR DYGRPLDEQE
1330 1340 1350 1360 1370 1380
SQFRERDIPS LPPLPPLPPL PPLDRYRDDR WREERNREHG YDRDFRDRGE LRIREYPERG
1390 1400 1410 1420 1430 1440
DTWREKRDYV PDRMDWERER LSDRWYPSDV DRHSPMAEHM PSSHHSSEMM GSDASLDSDQ
1450 1460 1470 1480 1490 1500
GLGGVMVLSQ RQHEIILKAA QELKMLREQK EQLQKMKDFG SEPQMADHLP PQESRLQNTS
1510 1520 1530 1540 1550 1560
SRPGMYPPPG SYRPPPPMGK PPGSIVRPSA PPARSSVPVT RPPVPIPPPP PPPPLPPPPP
1570 1580 1590 1600 1610 1620
VIKPQTSAVE QERWDEDSFY GLWDTNDEQG LNSEFKSETA AIPSAPVLPP PPVHSSIPPP
1630 1640 1650 1660 1670 1680
GPVPMGMPPM SKPPPVQQTV DYGHGRDIST NKVEQIPYGE RITLRPDPLP ERSTFETEHA
1690 1700 1710 1720 1730 1740
GQRDRYDRER DREPYFDRQS NVIADHRDFK RDRETHRDRD RDRGVIDYDR DRFDRERRPR
1750 1760 1770 1780 1790 1800
DDRAQSYRDK KDHSSSRRGG FDRPSYDRKS DRPVYEGPSM FGGERRTYPE ERMPLPAPSL
1810 1820 1830 1840 1850 1860
SHQPPPAPRV EKKPESKNVD DILKPPGRES RPERIVVIMR GLPGSGKTHV AKLIRDKEVE
1870 1880 1890 1900 1910 1920
FGGPAPRVLS LDDYFITEVE KEEKDPDSGK KVKKKVMEYE YEAEMEETYR TSMFKTFKKT
1930 1940 1950 1960 1970 1980
LDDGFFPFII LDAINDRVRH FDQFWSAAKT KGFEVYLAEM SADNQTCGKR NIHGRKLKEI
1990 2000 2010 2020 2030 2040
NKMADHWETA PRHMMRLDIR SLLQDAAIEE VEMEDFDANI EEQKEEKKDA EEEESELGYI
2050 2060 2070 2080 2090 2100
PKSKWEMDTS EAKLDKLDGL RTGTKRKRDW EAIASRMEDY LQLPDDYDTR ASEPGKKRVR
2110 2120 2130 2140
WADLEEKKDA DRKRAIGFVV GQTDWEKITD ESGHLAEKAL NRTKYI
10 20 30 40 50 60
MYPNWGRYGG SSHYPPPPVP PPPPVALPEA SPGPGYSSST TPAAPSSSGF MSFREQHLAQ
70 80 90 100 110 120
LQQLQQMHQK QMQCVLQPHH LPPPPLPPPP VMPGGGYGDW QPPPPPMPPP PGPALSYQKQ
130 140 150 160 170 180
QQYKHQMLHH QRDGPPGLVP MELESPPESP PVPPGSYMPP SQSYMPPPQP PPSYYPPTSS
190 200 210 220 230 240
QPYLPPAQPS PSQSPPSQSY LAPTPSYSSS SSSSQSYLSH SQSYLPSSQA SPSRPSQGHS
250 260 270 280 290 300
KSQLLAPPPP SAPPGNKTTV QQEPLESGAK NKSTEQQQAA PEPDPSTMTP QEQQQYWYRQ
310 320 330 340 350 360
HLLSLQQRTK VHLPGHKKGP VVAKDTPEPV KEEVTVPATS QVPESPSSEE PPLPPPNEEV
370 380 390 400 410 420
PPPLPPEEPQ SEDPEEDARL KQLQAAAAHW QQHQQHRVGF QYQGIMQKHT QLQQILQQYQ
430 440 450 460 470 480
QIIQPPPHIQ TMSVDMQLRH YEMQQQQFQH LYQEWEREFQ LWEEQLHSYP HKDQLQEYEK
490 500 510 520 530 540
QWKTWQGHMK ATQSYLQEKV NSFQNMKNQY MGNMSMPPPF VPYSQMPPPL PTMPPPVLPP
550 560 570 580 590 600
SLPPPVMPPA LPATVPPPGM PPPVMPPSLP TSVPPPGMPP SLSSAGPPPV LPPPSLSSAG
610 620 630 640 650 660
PPPVLPPPSL SSTAPPPVMP LPPLSSATPP PGIPPPGVPQ GIPPQLTAAP VPPASSSQSS
670 680 690 700 710 720
QVPEKPRPAL LPTPVSFGSA PPTTYHPPLQ SAGPSEQVNS KAPLSKSALP YSSFSSDQGL
730 740 750 760 770 780
GESSAAPSQP ITAVKDMPVR SGGLLPDPPR SSYLESPRGP RFDGPRRFED LGSRCEGPRP
790 800 810 820 830 840
KGPRFEGNRP DGPRPRYEGH PAEGTKSKWG MIPRGPASQF YITPSTSLSP RQSGPQWKGP
850 860 870 880 890 900
KPAFGQQHQQ QPKSQAEPLS GNKEPLADTS SNQQKNFKMQ SAAFSIAADV KDVKAAQSNE
910 920 930 940 950 960
NLSDSQQEPP KSEVSEGPVE PSNWDQNVQS METQIDKAQA VTQPVPLANK PVPAQSTFPS
970 980 990 1000 1010 1020
KTGGMEGGTA VATSSLTADN DFKPVGIGLP HSENNQDKGL PRPDNRDNRL EGNRGNSSSY
1030 1040 1050 1060 1070 1080
RGPGQSRMED TRDKGLVNRG RGQAISRGPG LVKQEDFRDK MMGRREDSRE KMNRGEGSRD
1090 1100 1110 1120 1130 1140
RGLVRPGSSR EKVPGGLQGS QDRGAAGSRE RGPPRRAGSQ ERGPLRRAGS RERIPPRRAG
1150 1160 1170 1180 1190 1200
SRERGPPRGP GSRERGLGRS DFGRDRGPFR PEPGDGGEKM YPYHRDEPPR APWNHGEERG
1210 1220 1230 1240 1250 1260
HEEFPLDGRN APMERERLDD WDRERYWREC ERDYQDDTLE LYNREDRFSA PPSRSHDGDR
1270 1280 1290 1300 1310 1320
RGPWWDDWER DQDMDEDYNR EMERDMDRDV DRISRPMDMY DRSLDNEWDR DYGRPLDEQE
1330 1340 1350 1360 1370 1380
SQFRERDIPS LPPLPPLPPL PPLDRYRDDR WREERNREHG YDRDFRDRGE LRIREYPERG
1390 1400 1410 1420 1430 1440
DTWREKRDYV PDRMDWERER LSDRWYPSDV DRHSPMAEHM PSSHHSSEMM GSDASLDSDQ
1450 1460 1470 1480 1490 1500
GLGGVMVLSQ RQHEIILKAA QELKMLREQK EQLQKMKDFG SEPQMADHLP PQESRLQNTS
1510 1520 1530 1540 1550 1560
SRPGMYPPPG SYRPPPPMGK PPGSIVRPSA PPARSSVPVT RPPVPIPPPP PPPPLPPPPP
1570 1580 1590 1600 1610 1620
VIKPQTSAVE QERWDEDSFY GLWDTNDEQG LNSEFKSETA AIPSAPVLPP PPVHSSIPPP
1630 1640 1650 1660 1670 1680
GPVPMGMPPM SKPPPVQQTV DYGHGRDIST NKVEQIPYGE RITLRPDPLP ERSTFETEHA
1690 1700 1710 1720 1730 1740
GQRDRYDRER DREPYFDRQS NVIADHRDFK RDRETHRDRD RDRGVIDYDR DRFDRERRPR
1750 1760 1770 1780 1790 1800
DDRAQSYRDK KDHSSSRRGG FDRPSYDRKS DRPVYEGPSM FGGERRTYPE ERMPLPAPSL
1810 1820 1830 1840 1850 1860
SHQPPPAPRV EKKPESKNVD DILKPPGRES RPERIVVIMR GLPGSGKTHV AKLIRDKEVE
1870 1880 1890 1900 1910 1920
FGGPAPRVLS LDDYFITEVE KEEKDPDSGK KVKKKVMEYE YEAEMEETYR TSMFKTFKKT
1930 1940 1950 1960 1970 1980
LDDGFFPFII LDAINDRVRH FDQFWSAAKT KGFEVYLAEM SADNQTCGKR NIHGRKLKEI
1990 2000 2010 2020 2030 2040
NKMADHWETA PRHMMRLDIR SLLQDAAIEE VEMEDFDANI EEQKEEKKDA EEEESELGYI
2050 2060 2070 2080 2090 2100
PKSKWEMDTS EAKLDKLDGL RTGTKRKRDW EAIASRMEDY LQLPDDYDTR ASEPGKKRVR
2110 2120 2130 2140
WADLEEKKDA DRKRAIGFVV GQTDWEKITD ESGHLAEKAL NRTKYI
10 20 30 40 50 60
MYPNWGRYGG SSHYPPPPVP PPPPVALPEA SPGPGYSSST TPAAPSSSGF MSFREQHLAQ
70 80 90 100 110 120
LQQLQQMHQK QMQCVLQPHH LPPPPLPPPP VMPGGGYGDW QPPPPPMPPP PGPALSYQKQ
130 140 150 160 170 180
QQYKHQMLHH QRDGPPGLVP MELESPPESP PVPPGSYMPP SQSYMPPPQP PPSYYPPTSS
190 200 210 220 230 240
QPYLPPAQPS PSQSPPSQSY LAPTPSYSSS SSSSQSYLSH SQSYLPSSQA SPSRPSQGHS
250 260 270 280 290 300
KSQLLAPPPP SAPPGNKTTV QQEPLESGAK NKSTEQQQAA PEPDPSTMTP QEQQQYWYRQ
310 320 330 340 350 360
HLLSLQQRTK VHLPGHKKGP VVAKDTPEPV KEEVTVPATS QVPESPSSEE PPLPPPNEEV
370 380 390 400 410 420
PPPLPPEEPQ SEDPEEDARL KQLQAAAAHW QQHQQHRVGF QYQGIMQKHT QLQQILQQYQ
430 440 450 460 470 480
QIIQPPPHIQ TMSVDMQLRH YEMQQQQFQH LYQEWEREFQ LWEEQLHSYP HKDQLQEYEK
490 500 510 520 530 540
QWKTWQGHMK ATQSYLQEKV NSFQNMKNQY MGNMSMPPPF VPYSQMPPPL PTMPPPVLPP
550 560 570 580 590 600
SLPPPVMPPA LPATVPPPGM PPPVMPPSLP TSVPPPGMPP SLSSAGPPPV LPPPSLSSAG
610 620 630 640 650 660
PPPVLPPPSL SSTAPPPVMP LPPLSSATPP PGIPPPGVPQ GIPPQLTAAP VPPASSSQSS
670 680 690 700 710 720
QVPEKPRPAL LPTPVSFGSA PPTTYHPPLQ SAGPSEQVNS KAPLSKSALP YSSFSSDQGL
730 740 750 760 770 780
GESSAAPSQP ITAVKDMPVR SGGLLPDPPR SSYLESPRGP RFDGPRRFED LGSRCEGPRP
790 800 810 820 830 840
KGPRFEGNRP DGPRPRYEGH PAEGTKSKWG MIPRGPASQF YITPSTSLSP RQSGPQWKGP
850 860 870 880 890 900
KPAFGQQHQQ QPKSQAEPLS GNKEPLADTS SNQQKNFKMQ SAAFSIAADV KDVKAAQSNE
910 920 930 940 950 960
NLSDSQQEPP KSEVSEGPVE PSNWDQNVQS METQIDKAQA VTQPVPLANK PVPAQSTFPS
970 980 990 1000 1010 1020
KTGGMEGGTA VATSSLTADN DFKPVGIGLP HSENNQDKGL PRPDNRDNRL EGNRGNSSSY
1030 1040 1050 1060 1070 1080
RGPGQSRMED TRDKGLVNRG RGQAISRGPG LVKQEDFRDK MMGRREDSRE KMNRGEGSRD
1090 1100 1110 1120 1130 1140
RGLVRPGSSR EKVPGGLQGS QDRGAAGSRE RGPPRRAGSQ ERGPLRRAGS RERIPPRRAG
1150 1160 1170 1180 1190 1200
SRERGPPRGP GSRERGLGRS DFGRDRGPFR PEPGDGGEKM YPYHRDEPPR APWNHGEERG
1210 1220 1230 1240 1250 1260
HEEFPLDGRN APMERERLDD WDRERYWREC ERDYQDDTLE LYNREDRFSA PPSRSHDGDR
1270 1280 1290 1300 1310 1320
RGPWWDDWER DQDMDEDYNR EMERDMDRDV DRISRPMDMY DRSLDNEWDR DYGRPLDEQE
1330 1340 1350 1360 1370 1380
SQFRERDIPS LPPLPPLPPL PPLDRYRDDR WREERNREHG YDRDFRDRGE LRIREYPERG
1390 1400 1410 1420 1430 1440
DTWREKRDYV PDRMDWERER LSDRWYPSDV DRHSPMAEHM PSSHHSSEMM GSDASLDSDQ
1450 1460 1470 1480 1490 1500
GLGGVMVLSQ RQHEIILKAA QELKMLREQK EQLQKMKDFG SEPQMADHLP PQESRLQNTS
1510 1520 1530 1540 1550 1560
SRPGMYPPPG SYRPPPPMGK PPGSIVRPSA PPARSSVPVT RPPVPIPPPP PPPPLPPPPP
1570 1580 1590 1600 1610 1620
VIKPQTSAVE QERWDEDSFY GLWDTNDEQG LNSEFKSETA AIPSAPVLPP PPVHSSIPPP
1630 1640 1650 1660 1670 1680
GPVPMGMPPM SKPPPVQQTV DYGHGRDIST NKVEQIPYGE RITLRPDPLP ERSTFETEHA
1690 1700 1710 1720 1730 1740
GQRDRYDRER DREPYFDRQS NVIADHRDFK RDRETHRDRD RDRGVIDYDR DRFDRERRPR
1750 1760 1770 1780 1790 1800
DDRAQSYRDK KDHSSSRRGG FDRPSYDRKS DRPVYEGPSM FGGERRTYPE ERMPLPAPSL
1810 1820 1830 1840 1850 1860
SHQPPPAPRV EKKPESKNVD DILKPPGRES RPERIVVIMR GLPGSGKTHV AKLIRDKEVE
1870 1880 1890 1900 1910 1920
FGGPAPRVLS LDDYFITEVE KEEKDPDSGK KVKKKVMEYE YEAEMEETYR TSMFKTFKKT
1930 1940 1950 1960 1970 1980
LDDGFFPFII LDAINDRVRH FDQFWSAAKT KGFEVYLAEM SADNQTCGKR NIHGRKLKEI
1990 2000 2010 2020 2030 2040
NKMADHWETA PRHMMRLDIR SLLQDAAIEE VEMEDFDANI EEQKEEKKDA EEEESELGYI
2050 2060 2070 2080 2090 2100
PKSKWEMDTS EAKLDKLDGL RTGTKRKRDW EAIASRMEDY LQLPDDYDTR ASEPGKKRVR
2110 2120 2130 2140
WADLEEKKDA DRKRAIGFVV GQTDWEKITD ESGHLAEKAL NRTKYI
Protein Neighborhood
Domains & Features
16 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P49750-1-acetylation | MYPNWG... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
P49750-1-acetylation | MYPNWG... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt179114 | ||
P49750-1-acetylation | MYPNWG... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt179115 | ||
P49750-1-unknown | MYPNWG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P49750-1-unknown | MYPNWG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt94881 | |||
P49750-1-unknown | MYPNWG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt94882 | |||
P49750-219-unknown | SHSQSY... | 219 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173458 | |||
P49750-219-unknown | SHSQSY... | 219 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173459 | |||
P49750-219- | SHSQSY... | 219 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P49750-483- | KTWQGH... | 483 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P49750-483-unknown | KTWQGH... | 483 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173456 | |||
P49750-483-unknown | KTWQGH... | 483 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173455 | |||
P49750-604- | VLPPPS... | 604 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
P49750-604-unknown | VLPPPS... | 604 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165912 | |||
P49750-604-unknown | VLPPPS... | 604 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165911 | |||
P49750-745-unknown | LPDPPR... | 745 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P49750-745-unknown | LPDPPR... | 745 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162308 | |||
P49750-745-unknown | LPDPPR... | 745 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162307 | |||
P49750-745- | LPDPPR... | 745 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
P49750-745- | LPDPPR... | 745 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
P49750-745- | LPDPPR... | 745 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P49750-745- | LPDPPR... | 745 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
P49750-745- | LPDPPR... | 745 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P49750-745- | LPDPPR... | 745 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P49750-745- | LPDPPR... | 745 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P49750-745- | LPDPPR... | 745 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P49750-746-unknown | PDPPRS... | 746 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165286 | |||
P49750-746-unknown | PDPPRS... | 746 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165285 | |||
P49750-746- | PDPPRS... | 746 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
P49750-1119-unknown | SQERGP... | 1119 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5935 | |||
P49750-1119-unknown | SQERGP... | 1119 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157438 | |||
P49750-1119-unknown | SQERGP... | 1119 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157917 | |||
P49750-1239-unknown | LELYNR... | 1239 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11598 | |||
P49750-1239-unknown | LELYNR... | 1239 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157756 | |||
P49750-1239-unknown | LELYNR... | 1239 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158097 | |||
P49750-1397-unknown | ERERLS... | 1397 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000448367 | |||
P49750-1397-unknown | ERERLS... | 1397 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt129434 | |||
P49750-1397-unknown | ERERLS... | 1397 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt129435 | |||
P49750-1882-unknown | EEKDPD... | 1882 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10092 | |||
P49750-1882-unknown | EEKDPD... | 1882 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158889 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...PRRAGS | 1118 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5935 | |||
...YQDDTL | 1238 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11598 | |||
...TEVEKE | 1881 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10092 | |||
...AAKTKG | 1951 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...AAKTKG | 1951 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt90500 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATL1_HUMAN | 1118 | RAGS.|.SQER | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
GRAB_HUMAN | 1238 | DDTL.|.LELY | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
GRAA_HUMAN | 1881 | VEKE.|.EEKD | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:The substrate specificity profi... (S01.135) | 20536382, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|