P23396: 40S ribosomal protein S3

General Information

Protein names	- 40S ribosomal protein S3 - 4.2.99.18 {ECO:0000269\|PubMed:7775413} - Small ribosomal subunit protein uS3 {ECO:0000303\|PubMed:24524803}
Gene names	RPS3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P23396

21 N-termini

8 C-termini

8 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAVQISKKRK FVADGIFKAE LNEFLTRELA EDGYSGVEVR VTPTRTEIII LATRTQNVLG
        70         80         90        100        110        120
EKGRRIRELT AVVQKRFGFP EGSVELYAEK VATRGLCAIA QAESLRYKLL GGLAVRRACY
       130        140        150        160        170        180
GVLRFIMESG AKGCEVVVSG KLRGQRAKSM KFVDGLMIHS GDPVNYYVDT AVRHVLLRQG
       190        200        210        220        230        240
VLGIKVKIML PWDPTGKIGP KKPLPDHVSI VEPKDEILPT TPISEQKGGK PEPPAMPQPV

PTA

Isoforms

- Isoform 2 of 40S ribosomal protein S3

Sequence View

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Protein Neighborhood

Domains & Features

21 N-termini - 8 C-termini - 8 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P23396-2-unknown	MAVQIS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P23396-1-unknown	MAVQIS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88266
P23396-2-Acetylation	AVQISK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P23396-2-Acetylation	AVQISK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P23396-2-Acetylation	AVQISK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P23396-2-Acetylation	AVQISK...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110701
P23396-9-unknown	RKFVAD...	9		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P23396-9-unknown	RKFVAD...	9		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194845
P23396-10-	KFVADG...	10			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P23396-10-unknown	KFVADG...	10		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164899
P23396-14-unknown	DGIFKA...	14		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17514
P23396-14-unknown	DGIFKA...	14		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18933
P23396-14-unknown	DGIFKA...	14		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136477
P23396-31-unknown	EDGYSG...	31		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7380
P23396-31-unknown	EDGYSG...	31		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137655
P23396-33-	GYSGVE...	33			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P23396-33-unknown	GYSGVE...	33		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11346
P23396-33-unknown	GYSGVE...	33		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137781
P23396-95-unknown	GLCAIA...	95		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10035
P23396-95-unknown	GLCAIA...	95		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196868
P23396-98-unknown	AIAQAE...	98		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5714
P23396-98-unknown	AIAQAE...	98		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143168
P23396-99-unknown	IAQAES...	99		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3719
P23396-99-unknown	IAQAES...	99		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143242
P23396-111-unknown	GGLAVR...	111		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P23396-111-unknown	GGLAVR...	111		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197115
P23396-135-unknown	EVVVSG...	135		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14040
P23396-135-unknown	EVVVSG...	135		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144797
P23396-198-unknown	IGPKKP...	198		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169765
P23396-198-	IGPKKP...	198			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P23396-202-	KPLPDH...	202			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P23396-202-unknown	KPLPDH...	202		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169763
P23396-228-	GGKPEP...	228			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P23396-228-unknown	GGKPEP...	228		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169761

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RKFVAD	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17514
...RKFVAD	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18933
...TRELAE	30	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7380
...TRELAE	30	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120651
...ELAEDG	32	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11346
...ELAEDG	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120781
...KVATRG	94	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10035
...TRGLCA	97	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5714
...RGLCAI	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3719
...GAKGCE	134	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14040
...GAKGCE	134	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128072
...PVPTA	243	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PVPTA	243	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83884

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	13	FVAD.\|.DGIF	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	13	FVAD.\|.DGIF	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATS_HUMAN	30	ELAE.\|.EDGY	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	32	AEDG.\|.GYSG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAA_HUMAN	94	ATRG.\|.GLCA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CATL1_HUMAN	97	GLCA.\|.AIAQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	98	LCAI.\|.IAQA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAM_HUMAN	134	KGCE.\|.EVVV	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)