P40429: 60S ribosomal protein L13a

General Information

Protein names	- 60S ribosomal protein L13a - 23 kDa highly basic protein - Large ribosomal subunit protein uL13 {ECO:0000303\|PubMed:24524803}
Gene names	RPL13A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P40429

8 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAEVQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN KLKYLAFLRK
        70         80         90        100        110        120
RMNTNPSRGP YHFRAPSRIF WRTVRGMLPH KTKRGQAALD RLKVFDGIPP PYDKKKRMVV
       130        140        150        160        170        180
PAALKVVRLK PTRKFAYLGR LAHEVGWKYQ AVTATLEEKR KEKAKIHYRK KKQLMRLRKQ
       190        200
AEKNVEKKID KYTEVLKTHG LLV

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P40429-2-unknown	MAEVQV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P40429-2-Acetylation	AEVQVL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P40429-2-Acetylation	AEVQVL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P40429-2-Acetylation	AEVQVL...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P40429-2-Acetylation	AEVQVL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P40429-58-unknown	LRKRMN...	58		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14118
P40429-106-unknown	DGIPPP...	106		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19095
P40429-118-	MVVPAA...	118			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P40429-118-	MVVPAA...	118			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P40429-123-unknown	ALKVVR...	123		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11493
P40429-149-unknown	YQAVTA...	149		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10070
P40429-176-unknown	RLRKQA...	176		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14119

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KYLAFL	57	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14118
...RLKVFD	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19095
...MVVPAA	122	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11493
...EVGWKY	148	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10070
...KKQLMR	175	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14119
...HGLLV	203	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	57	LAFL.\|.LRKR	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
MEP1B_HUMAN	105	KVFD.\|.DGIP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	122	VPAA.\|.ALKV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAA_HUMAN	148	GWKY.\|.YQAV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	175	QLMR.\|.RLRK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)