Q9BVJ6: U3 small nucleolar RNA-associated protein 14 homolog A
Protein names | - U3 small nucleolar RNA-associated protein 14 homolog A - Antigen NY-CO-16 - Serologically defined colon cancer antigen 16 |
---|---|
Gene names | UTP14A |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9BVJ6 |
8
N-termini
4
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTANRLAESL LALSQQEELA DLPKDYLLSE SEDEGDNDGE RKHQKLLEAI SSLDGKNRRK
70 80 90 100 110 120
LAERSEASLK VSEFNVSSEG SGEKLVLADL LEPVKTSSSL ATVKKQLSRV KSKKTVELPL
130 140 150 160 170 180
NKEEIERIHR EVAFNKTAQV LSKWDPVVLK NRQAEQLVFP LEKEEPAIAP IEHVLSGWKA
190 200 210 220 230 240
RTPLEQEIFN LLHKNKQPVT DPLLTPVEKA SLRAMSLEEA KMRRAELQRA RALQSYYEAK
250 260 270 280 290 300
ARREKKIKSK KYHKVVKKGK AKKALKEFEQ LRKVNPAAAL EELEKIEKAR MMERMSLKHQ
310 320 330 340 350 360
NSGKWAKSKA IMAKYDLEAR QAMQEQLSKN KELTQKLQVA SESEEEEGGT EDVEELLVPD
370 380 390 400 410 420
VVNEVQMNAD GPNPWMLRSC TSDTKEAATQ EDPEQLPELE AHGVSESEGE ERPVAEEEIL
430 440 450 460 470 480
LREFEERRSL RKRSELSQDA EPAGSQETKD SGSQEVLSEL RVLSQKLKEN HQSRKQKASS
490 500 510 520 530 540
EGTIPQVQRE EPAPEEEEPL LLQRPERVQT LEELEELGKE ECFQNKELPR PVLEGQQSER
550 560 570 580 590 600
TPNNRPDAPK EKKKKEQMID LQNLLTTQSP SVKSLAVPTI EELEDEEERN HRQMIKEAFA
610 620 630 640 650 660
GDDVIRDFLK EKREAVEASK PKDVDLTLPG WGEWGGVGLK PSAKKRRRFL IKAPEGPPRK
670 680 690 700 710 720
DKNLPNVIIN EKRNIHAAAH QVRVLPYPFT HHWQFERTIQ TPIGSTWNTQ RAFQKLTTPK
730 740 750 760 770
VVTKPGHIIN PIKAEDVGYR SSSRSDLSVI QRNPKRITTR HKKQLKKCSV D
Isoforms
- Isoform 2 of U3 small nucleolar RNA-associated protein 14 homolog A - Isoform 3 of U3 small nucleolar RNA-associated protein 14 homolog ASequence View
10 20 30 40 50 60
MTANRLAESL LALSQQEELA DLPKDYLLSE SEDEGDNDGE RKHQKLLEAI SSLDGKNRRK
70 80 90 100 110 120
LAERSEASLK VSEFNVSSEG SGEKLVLADL LEPVKTSSSL ATVKKQLSRV KSKKTVELPL
130 140 150 160 170 180
NKEEIERIHR EVAFNKTAQV LSKWDPVVLK NRQAEQLVFP LEKEEPAIAP IEHVLSGWKA
190 200 210 220 230 240
RTPLEQEIFN LLHKNKQPVT DPLLTPVEKA SLRAMSLEEA KMRRAELQRA RALQSYYEAK
250 260 270 280 290 300
ARREKKIKSK KYHKVVKKGK AKKALKEFEQ LRKVNPAAAL EELEKIEKAR MMERMSLKHQ
310 320 330 340 350 360
NSGKWAKSKA IMAKYDLEAR QAMQEQLSKN KELTQKLQVA SESEEEEGGT EDVEELLVPD
370 380 390 400 410 420
VVNEVQMNAD GPNPWMLRSC TSDTKEAATQ EDPEQLPELE AHGVSESEGE ERPVAEEEIL
430 440 450 460 470 480
LREFEERRSL RKRSELSQDA EPAGSQETKD SGSQEVLSEL RVLSQKLKEN HQSRKQKASS
490 500 510 520 530 540
EGTIPQVQRE EPAPEEEEPL LLQRPERVQT LEELEELGKE ECFQNKELPR PVLEGQQSER
550 560 570 580 590 600
TPNNRPDAPK EKKKKEQMID LQNLLTTQSP SVKSLAVPTI EELEDEEERN HRQMIKEAFA
610 620 630 640 650 660
GDDVIRDFLK EKREAVEASK PKDVDLTLPG WGEWGGVGLK PSAKKRRRFL IKAPEGPPRK
670 680 690 700 710 720
DKNLPNVIIN EKRNIHAAAH QVRVLPYPFT HHWQFERTIQ TPIGSTWNTQ RAFQKLTTPK
730 740 750 760 770
VVTKPGHIIN PIKAEDVGYR SSSRSDLSVI QRNPKRITTR HKKQLKKCSV D
10 20 30 40 50 60
MTANRLAESL LALSQQEELA DLPKDYLLSE SEDEGDNDGE RKHQKLLEAI SSLDGKNRRK
70 80 90 100 110 120
LAERSEASLK VSEFNVSSEG SGEKLVLADL LEPVKTSSSL ATVKKQLSRV KSKKTVELPL
130 140 150 160 170 180
NKEEIERIHR EVAFNKTAQV LSKWDPVVLK NRQAEQLVFP LEKEEPAIAP IEHVLSGWKA
190 200 210 220 230 240
RTPLEQEIFN LLHKNKQPVT DPLLTPVEKA SLRAMSLEEA KMRRAELQRA RALQSYYEAK
250 260 270 280 290 300
ARREKKIKSK KYHKVVKKGK AKKALKEFEQ LRKVNPAAAL EELEKIEKAR MMERMSLKHQ
310 320 330 340 350 360
NSGKWAKSKA IMAKYDLEAR QAMQEQLSKN KELTQKLQVA SESEEEEGGT EDVEELLVPD
370 380 390 400 410 420
VVNEVQMNAD GPNPWMLRSC TSDTKEAATQ EDPEQLPELE AHGVSESEGE ERPVAEEEIL
430 440 450 460 470 480
LREFEERRSL RKRSELSQDA EPAGSQETKD SGSQEVLSEL RVLSQKLKEN HQSRKQKASS
490 500 510 520 530 540
EGTIPQVQRE EPAPEEEEPL LLQRPERVQT LEELEELGKE ECFQNKELPR PVLEGQQSER
550 560 570 580 590 600
TPNNRPDAPK EKKKKEQMID LQNLLTTQSP SVKSLAVPTI EELEDEEERN HRQMIKEAFA
610 620 630 640 650 660
GDDVIRDFLK EKREAVEASK PKDVDLTLPG WGEWGGVGLK PSAKKRRRFL IKAPEGPPRK
670 680 690 700 710 720
DKNLPNVIIN EKRNIHAAAH QVRVLPYPFT HHWQFERTIQ TPIGSTWNTQ RAFQKLTTPK
730 740 750 760 770
VVTKPGHIIN PIKAEDVGYR SSSRSDLSVI QRNPKRITTR HKKQLKKCSV D
Protein Neighborhood
Domains & Features
8 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9BVJ6-1-unknown | MTANRL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9BVJ6-1-unknown | MTANRL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt94006 | |||
Q9BVJ6-27-unknown | LLSESE... | 27 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10533 | |||
Q9BVJ6-27-unknown | LLSESE... | 27 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt137323 | |||
Q9BVJ6-214-unknown | AMSLEE... | 214 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10535 | |||
Q9BVJ6-214-unknown | AMSLEE... | 214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt138813 | |||
Q9BVJ6-214-unknown | AMSLEE... | 214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt145206 | |||
Q9BVJ6-313-unknown | AKYDLE... | 313 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14962 | |||
Q9BVJ6-313-unknown | AKYDLE... | 313 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144530 | |||
Q9BVJ6-313-unknown | AKYDLE... | 313 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148841 | |||
Q9BVJ6-367- | MNADGP... | 367 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9BVJ6-367-unknown | MNADGP... | 367 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167988 | |||
Q9BVJ6-367-unknown | MNADGP... | 367 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167987 | |||
Q9BVJ6-574- | SLAVPT... | 574 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9BVJ6-574-unknown | SLAVPT... | 574 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173971 | |||
Q9BVJ6-574-unknown | SLAVPT... | 574 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173970 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LPKDYL | 26 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10533 | |||
...LPKDYL | 26 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt120263 | |||
...KASLRA | 213 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10535 | |||
...KASLRA | 213 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt121872 | |||
...KASLRA | 213 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt128495 | |||
...SKAIMA | 312 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14962 | |||
...SKAIMA | 312 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127797 | |||
...SKAIMA | 312 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132218 | |||
...KCSVD | 771 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...KCSVD | 771 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89623 | |||
...KCSVD | 771 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89624 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAA_HUMAN | 26 | KDYL.|.LLSE | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:The substrate specificity profi... (S01.135) | 20536382, |
GRAA_HUMAN | 213 | SLRA.|.AMSL | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:The substrate specificity profi... (S01.135) | 20536382, |
GRAM_HUMAN | 312 | AIMA.|.AKYD | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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