Q53F19: Nuclear cap-binding protein subunit 3 {ECO:0000312|HGNC:HGNC:24612}

General Information

Protein names	- Nuclear cap-binding protein subunit 3 {ECO:0000312\|HGNC:HGNC:24612} - Protein ELG
Gene names	C17orf85
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q53F19

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Uncharacterized protein C17orf85 - Isoform 2 of Nuclear cap-binding protein subunit 3

Sequence View

        10         20         30         40         50         60
MAAVRGLRVS VKAEAPAGPA LGLPSPEAES GVDRGEPEPM EVEEGELEIV PVRRSLKELI
        70         80         90        100        110        120
PDTSRRYENK AGSFITGIDV TSKEAIEKKE QRAKRFHFRS EVNLAQRNVA LDRDMMKKAI
       130        140        150        160        170        180
PKVRLETIYI CGVDEMSTQD VFSYFKEYPP AHIEWLDDTS CNVVWLDEMT ATRALINMSS
       190        200        210        220        230        240
LPAQDKIRSR DASEDKSAEK RKKDKQEDSS DDDEAEEGEV EDENSSDVEL DTLSQVEEES
       250        260        270        280        290        300
LLRNDLRPAN KLAKGNRLFM RFATKDDKKE LGAARRSQYY MKYGNPNYGG MKGILSNSWK
       310        320        330        340        350        360
RRYHSRRIQR DVIKKRALIG DDVGLTSYKH RHSGLVNVPE EPIEEEEEEE EEEEEEEEED
       370        380        390        400        410        420
QDMDADDRVV VEYHEELPAL KQPRERSASR RSSASSSDSD EMDYDLELKM ISTPSPKKSM
       430        440        450        460        470        480
KMTMYADEVE SQLKNIRNSM RADSVSSSNI KNRIGNKLPP EKFADVRHLL DEKRQHSRPR
       490        500        510        520        530        540
PPVSSTKSDI RQRLGKRPHS PEKAFSSNPV VRREPSSDVH SRLGVPRQDS KGLYADTREK
       550        560        570        580        590        600
KSGNLWTRLG SAPKTKEKNT KKVDHRAPGA EEDDSELQRA WGALIKEKEQ SRQKKSRLDN
       610        620
LPSLQIEVSR ESSSGSEAES         10         20         30         40         50         60
MAAVRGLRVS VKAEAPAGPA LGLPSPEAES GVDRGEPEPM EVEEGELEIV PVRRSLKELI
        70         80         90        100        110        120
PDTSRRYENK AGSFITGIDV TSKEAIEKKE QRAKRFHFRS EVNLAQRNVA LDRDMMKKAI
       130        140        150        160        170        180
PKVRLETIYI CGVDEMSTQD VFSYFKEYPP AHIEWLDDTS CNVVWLDEMT ATRALINMSS
       190        200        210        220        230        240
LPAQDKIRSR DASEDKSAEK RKKDKQEDSS DDDEAEEGEV EDENSSDVEL DTLSQVEEES
       250        260        270        280        290        300
LLRNDLRPAN KLAKGNRLFM RFATKDDKKE LGAARRSQYY MKYGNPNYGG MKGILSNSWK
       310        320        330        340        350        360
RRYHSRRIQR DVIKKRALIG DDVGLTSYKH RHSGLVNVPE EPIEEEEEEE EEEEEEEEED
       370        380        390        400        410        420
QDMDADDRVV VEYHEELPAL KQPRERSASR RSSASSSDSD EMDYDLELKM ISTPSPKKSM
       430        440        450        460        470        480
KMTMYADEVE SQLKNIRNSM RADSVSSSNI KNRIGNKLPP EKFADVRHLL DEKRQHSRPR
       490        500        510        520        530        540
PPVSSTKSDI RQRLGKRPHS PEKAFSSNPV VRREPSSDVH SRLGVPRQDS KGLYADTREK
       550        560        570        580        590        600
KSGNLWTRLG SAPKTKEKNT KKVDHRAPGA EEDDSELQRA WGALIKEKEQ SRQKKSRLDN
       610        620
LPSLQIEVSR ESSSGSEAES

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q53F19-1-unknown	MAAVRG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q53F19-191-unknown	DASEDK...	191	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10334
Q53F19-232-unknown	TLSQVE...	232	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12457
Q53F19-232-	TLSQVE...	232		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q53F19-232-	TLSQVE...	232		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q53F19-232-	TLSQVE...	232		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q53F19-281-unknown	MKYGNP...	281	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71609

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KIRSRD	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10334
...DVELDT	231	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12457
...SEAES	620	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SEAES	620	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67227

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	190	RSRD.\|.DASE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	231	ELDT.\|.TLSQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)