TopFIND 4.0

P05114: Non-histone chromosomal protein HMG-14

General Information

Protein names	- Non-histone chromosomal protein HMG-14 - High mobility group nucleosome-binding domain-containing protein 1
Gene names	HMGN1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P05114

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MPKRKVSSAE GAAKEEPKRR SARLSAKPPA KVEAKPKKAA AKDKSSDKKV QTKGKRGAKG
70 80 90 100
KQAEVANQET KEDLPAENGE TKTEESPASD EAGEKEAKSD

Isoforms

Sequence View

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Evidence Codes:

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Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P05114-2-unknown	PKRKVS...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P05114-2-unknown	PKRKVS...	2		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P05114-26-	AKPPAK...	26			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P05114-26-	AKPPAK...	26			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P05114-45-unknown	SSDKKV...	45		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC9935
P05114-60-	GKQAEV...	60			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...AAKDKS	44	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC9935
	...EAKSD	100	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	44	KDKS.\|.SSDK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)