Q99877: Histone H2B type 1-N

General Information

Protein names	- Histone H2B type 1-N - Histone H2B.d - H2B/d
Gene names	HIST1H2BN
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99877

7 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPEPSKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSV YVYKVLKQVH PDTGISSKAM
        70         80         90        100        110        120
GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR LLLPGELAKH AVSEGTKAVT

KYTSSK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q99877-2-unknown	MPEPSK...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q99877-2-unknown	MPEPSK...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99877-2-Acetylation	PEPSKS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99877-2-Acetylation	PEPSKS...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q99877-6-unknown	KSAPAP...	6		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14907
Q99877-13-unknown	KGSKKA...	13		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10499
Q99877-22-unknown	AQKKDG...	22		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10500
Q99877-53-unknown	TGISSK...	53		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13151
Q99877-59-unknown	AMGIMN...	59		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10501

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MPEPSK	5	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14907
...APAPKK	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10499
...KAVTKA	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10500
...QVHPDT	52	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13151
...GISSKA	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10501
...YTSSK	126	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	5	EPSK.\|.KSAP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAA_HUMAN	12	APKK.\|.KGSK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	21	VTKA.\|.AQKK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	52	HPDT.\|.TGIS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAA_HUMAN	58	SSKA.\|.AMGI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)