Q6P1R4: tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like

General Information

Protein names	- tRNA-dihydrouridine(16/17) synthase NAD(P)(+)]-like - 1.3.1.- - tRNA-dihydrouridine synthase 1-like
Gene names	DUS1L
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6P1R4

3 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPKLQGFEFW SRTLRGARHV VAPMVDQSEL AWRLLSRRHG AQLCYTPMLH AQVFVRDANY
        70         80         90        100        110        120
RKENLYCEVC PEDRPLIVQF CANDPEVFVQ AALLAQDYCD AIDLNLGCPQ MIAKRGHYGA
       130        140        150        160        170        180
FLQDEWDLLQ RMILLAHEKL SVPVTCKIRV FPEIDKTVRY AQMLEKAGCQ LLTVHGRTKE
       190        200        210        220        230        240
QKGPLSGAAS WEHIKAVRKA VAIPVFANGN IQCLQDVERC LRDTGVQGVM SAEGNLHNPA
       250        260        270        280        290        300
LFEGRSPAVW ELAEEYLDIV REHPCPLSYV RAHLFKLWHH TLQVHQELRE ELAKVKTLEG
       310        320        330        340        350        360
IAAVSQELKL RCQEEISRQE GAKPTGDLPF HWICQPYIRP GPREGSKEKA GARSKRALEE
       370        380        390        400        410        420
EEGGTEVLSK NKQKKQLRNP HKTFDPSLKP KYAKCDQCGN PKGNRCVFSL CRGCCKKRAS
       430        440        450        460        470
KETADCPGHG LLFKTKLEKS LAWKEAQPEL QEPQPAAPGT PGGFSEVMGS ALA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6P1R4-1-unknown	MPKLQG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6P1R4-2-unknown	PKLQGF...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q6P1R4-344-unknown	EGSKEK...	344	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10362

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RYAQML	163	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463797
...VREHPC	264	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463180
...SQELKL	309	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463509
...RPGPRE	343	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10362
...GSALA	473	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	343	GPRE.\|.EGSK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)