44 N-termini - 18 C-termini - 22 Cleavages - 0 Substrates

N-termini

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...PGHLQE	6	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19698
	...PFEVLK	31	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14751
	...PFEVLK	31	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt120731
	...PFEVLK	31	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt120732
	...PFEVLK	31	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt120733
	...GPGAKS	52	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10430
	...GPGAKS	52	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122502
	...GPGAKS	52	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122503
	...GPGAKS	52	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122504
	...AKSAAQ	55	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7949
	...AKSAAQ	55	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14755
	...AKSAAQ	55	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122661
	...AKSAAQ	55	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122662
	...AKSAAQ	55	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122663
	...KSAAQA	56	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14759
	...KSAAQA	56	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122787
	...KSAAQA	56	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122788
	...KSAAQA	56	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122790
	...PLPPSV	85	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18037
	...PLPPSV	85	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19699
	...PLPPSV	85	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt124811
	...PLPPSV	85	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt124812
	...PLPPSV	85	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt124813
	...DKKEET	94	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18041
	...DKKEET	94	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19703
	...DKKEET	94	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt125320
	...DKKEET	94	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt125321
	...DKKEET	94	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt125322
	...VGRRPD	113	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10434
	...VGRRPD	113	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt126418
	...VGRRPD	113	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt126419
	...VGRRPD	113	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt126420
	...SFSHYS	207	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10438
	...SFSHYS	207	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130185
	...SHNWGT	225	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6583
	...QSNVTE	255	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7953
	...QSNVTE	255	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131768
	...SNVTEE	256	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7955
	...SNVTEE	256	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt131795
	...ENKENE	275	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18045
	...ENKENE	275	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19707
	...ENKENE	275	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132022
	...ENKENE	275	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132226
	...ENKENE	275	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132507
	...IRKPNE	312	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18049
	...IRKPNE	312	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19711
	...IRKPNE	312	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133012
	...IRKPNE	312	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133199
	...IRKPNE	312	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133436
	...AHAEDS	337	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1327
	...AHAEDS	337	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12884
	...AHAEDS	337	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133655
	...AHAEDS	337	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133800
	...AHAEDS	337	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133959
	...ASAPDV	397	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12888
	...ASAPDV	397	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134963
	...ASAPDV	397	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt135101
	...ASAPDV	397	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt135278
	...FPALA	408	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...FPALA	408	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt79787
	...FPALA	408	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt79786
	...FPALA	408	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt79785
	...FPALA	408		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
	...FPALA	408		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	6	HLQE.|.EGFG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAM_HUMAN	31	EVLK.|.KAAE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAA_HUMAN	52	GAKS.|.SAAQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CATS_HUMAN	55	SAAQ.|.QAAA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAM_HUMAN	55	SAAQ.|.QAAA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	56	AAQA.|.AAAQ	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
MEP1A_HUMAN	85	PPSV.|.VGVV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	85	PPSV.|.VGVV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	94	KEET.|.TQPP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	94	KEET.|.TQPP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAA_HUMAN	113	RRPD.|.DQQL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	207	SHYS.|.SGLK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CATL1_HUMAN	225	NWGT.|.TVKD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	255	NVTE.|.EETP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	256	VTEE.|.ETPE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	275	KENE.|.EVEE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	275	KENE.|.EVEE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	312	KPNE.|.EGAD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	312	KPNE.|.EGAD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CASP1_HUMAN	337	AEDS.|.SVMD	inferred from experiment	unknown	MEROPS	Wells JA	Agard NJ et al.:Inflammatory stimuli regulate c... (C14.001)	20173201,
GRAB_HUMAN	337	AEDS.|.SVMD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	397	APDV.|.VDDP	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)