P38159: RNA-binding motif protein, X chromosome
Protein names | - RNA-binding motif protein, X chromosome - Glycoprotein p43 - Heterogeneous nuclear ribonucleoprotein G - hnRNP G - RNA-binding motif protein, X chromosome, N-terminally processed |
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Gene names | RBMX |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P38159 |
25
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MVEADRPGKL FIGGLNTETN EKALEAVFGK YGRIVEVLLM KDRETNKSRG FAFVTFESPA
70 80 90 100 110 120
DAKDAARDMN GKSLDGKAIK VEQATKPSFE SGRRGPPPPP RSRGPPRGLR GGRGGSGGTR
130 140 150 160 170 180
GPPSRGGHMD DGGYSMNFNM SSSRGPLPVK RGPPPRSGGP PPKRSAPSGP VRSSSGMGGR
190 200 210 220 230 240
APVSRGRDSY GGPPRREPLP SRRDVYLSPR DDGYSTKDSY SSRDYPSSRD TRDYAPPPRD
250 260 270 280 290 300
YTYRDYGHSS SRDDYPSRGY SDRDGYGRDR DYSDHPSGGS YRDSYESYGN SRSAPPTRGP
310 320 330 340 350 360
PPSYGGSSRY DDYSSSRDGY GGSRDSYSSS RSDLYSSGRD RVGRQERGLP PSMERGYPPP
370 380 390
RDSYSSSSRG APRGGGRGGS RSDRGGGRSR Y
Isoforms
- Isoform 2 of RNA-binding motif protein, X chromosome - Isoform 3 of RNA-binding motif protein, X chromosomeSequence View
10 20 30 40 50 60
MVEADRPGKL FIGGLNTETN EKALEAVFGK YGRIVEVLLM KDRETNKSRG FAFVTFESPA
70 80 90 100 110 120
DAKDAARDMN GKSLDGKAIK VEQATKPSFE SGRRGPPPPP RSRGPPRGLR GGRGGSGGTR
130 140 150 160 170 180
GPPSRGGHMD DGGYSMNFNM SSSRGPLPVK RGPPPRSGGP PPKRSAPSGP VRSSSGMGGR
190 200 210 220 230 240
APVSRGRDSY GGPPRREPLP SRRDVYLSPR DDGYSTKDSY SSRDYPSSRD TRDYAPPPRD
250 260 270 280 290 300
YTYRDYGHSS SRDDYPSRGY SDRDGYGRDR DYSDHPSGGS YRDSYESYGN SRSAPPTRGP
310 320 330 340 350 360
PPSYGGSSRY DDYSSSRDGY GGSRDSYSSS RSDLYSSGRD RVGRQERGLP PSMERGYPPP
370 380 390
RDSYSSSSRG APRGGGRGGS RSDRGGGRSR Y
10 20 30 40 50 60
MVEADRPGKL FIGGLNTETN EKALEAVFGK YGRIVEVLLM KDRETNKSRG FAFVTFESPA
70 80 90 100 110 120
DAKDAARDMN GKSLDGKAIK VEQATKPSFE SGRRGPPPPP RSRGPPRGLR GGRGGSGGTR
130 140 150 160 170 180
GPPSRGGHMD DGGYSMNFNM SSSRGPLPVK RGPPPRSGGP PPKRSAPSGP VRSSSGMGGR
190 200 210 220 230 240
APVSRGRDSY GGPPRREPLP SRRDVYLSPR DDGYSTKDSY SSRDYPSSRD TRDYAPPPRD
250 260 270 280 290 300
YTYRDYGHSS SRDDYPSRGY SDRDGYGRDR DYSDHPSGGS YRDSYESYGN SRSAPPTRGP
310 320 330 340 350 360
PPSYGGSSRY DDYSSSRDGY GGSRDSYSSS RSDLYSSGRD RVGRQERGLP PSMERGYPPP
370 380 390
RDSYSSSSRG APRGGGRGGS RSDRGGGRSR Y
Protein Neighborhood
Domains & Features
25 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P38159-1- | MVEADR... | 1 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P38159-1- | MVEADR... | 1 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P38159-1- | MVEADR... | 1 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P38159-1- | MVEADR... | 1 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
P38159-1- | MVEADR... | 1 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P38159-1-Acetylation | MVEADR... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P38159-1-Acetylation | MVEADR... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt102913 | ||
P38159-1-Acetylation | MVEADR... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt102914 | ||
P38159-1-unknown | MVEADR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt87167 | |||
P38159-1-unknown | MVEADR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt87168 | |||
P38159-2-Acetylation | VEADRP... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P38159-2-Acetylation | VEADRP... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
P38159-2-Acetylation | VEADRP... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110894 | ||
P38159-2-Acetylation | VEADRP... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110895 | ||
P38159-78-unknown | AIKVEQ... | 78 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt177851 | |||
P38159-78- | AIKVEQ... | 78 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P38159-135- | SMNFNM... | 135 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P38159-135- | SMNFNM... | 135 | Subtiligase Based Positive Selection | Wells | THP_untreated | 23264352 | |||
P38159-135-unknown | SMNFNM... | 135 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P38159-135-unknown | SMNFNM... | 135 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159738 | |||
P38159-137-unknown | NFNMSS... | 137 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14104 | |||
P38159-137-unknown | NFNMSS... | 137 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P38159-137-unknown | NFNMSS... | 137 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt143637 | |||
P38159-165- | SAPSGP... | 165 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P38159-165- | SAPSGP... | 165 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P38159-165- | SAPSGP... | 165 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P38159-165-unknown | SAPSGP... | 165 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P38159-165-unknown | SAPSGP... | 165 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt161663 | |||
P38159-211-unknown | DDGYST... | 211 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10065 | |||
P38159-211-unknown | DDGYST... | 211 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt146515 | |||
P38159-211- | DDGYST... | 211 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P38159-234- | YAPPPR... | 234 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P38159-234-unknown | YAPPPR... | 234 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170290 | |||
P38159-265-unknown | GYGRDR... | 265 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173019 | |||
P38159-265- | GYGRDR... | 265 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P38159-284- | SYESYG... | 284 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P38159-284-unknown | SYESYG... | 284 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170288 | |||
P38159-293-unknown | SAPPTR... | 293 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt166768 | |||
P38159-293- | SAPPTR... | 293 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P38159-293- | SAPPTR... | 293 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P38159-293- | SAPPTR... | 293 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P38159-293- | SAPPTR... | 293 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P38159-319- | GYGGSR... | 319 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P38159-319- | GYGGSR... | 319 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P38159-319-unknown | GYGGSR... | 319 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174527 | |||
P38159-332-unknown | SDLYSS... | 332 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt169665 | |||
P38159-332- | SDLYSS... | 332 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GGYSMN | 136 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14104 | |||
...GGYSMN | 136 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt126879 | |||
...YLSPRD | 210 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10065 | |||
...YLSPRD | 210 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt129823 | |||
...GRSRY | 391 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...GRSRY | 391 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt82785 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 136 | YSMN.|.NFNM | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
GRAA_HUMAN | 210 | SPRD.|.DDGY | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:The substrate specificity profi... (S01.135) | 20536382, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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