P62280: 40S ribosomal protein S11

General Information

Protein names	- 40S ribosomal protein S11 - Small ribosomal subunit protein uS17 {ECO:0000303\|PubMed:24524803}
Gene names	RPS11
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62280

17 N-termini

10 C-termini

8 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADIQTERAY QKQPTIFQNK KRVLLGETGK EKLPRYYKNI GLGFKTPKEA IEGTYIDKKC
        70         80         90        100        110        120
PFTGNVSIRG RILSGVVTKM KMQRTIVIRR DYLHYIRKYN RFEKRHKNMS VHLSPCFRDV
       130        140        150
QIGDIVTVGE CRPLSKTVRF NVLKVTKAAG TKKQFQKF

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

17 N-termini - 10 C-termini - 8 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62280-2-unknown	MADIQT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62280-2-Acetylation	ADIQTE...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62280-2-Acetylation	ADIQTE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P62280-2-Acetylation	ADIQTE...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P62280-2-Acetylation	ADIQTE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P62280-8-unknown	RAYQKQ...	8		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P62280-9-unknown	AYQKQP...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10130
P62280-9-unknown	AYQKQP...	9			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P62280-9-	AYQKQP...	9			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P62280-23-	VLLGET...	23			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P62280-23-	VLLGET...	23			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P62280-25-unknown	LGETGK...	25		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14254
P62280-28-unknown	TGKEKL...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11769
P62280-32-unknown	KLPRYY...	32		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14255
P62280-36-	YYKNIG...	36			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P62280-39-	NIGLGF...	39			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P62280-43-	GFKTPK...	43			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P62280-50-	AIEGTY...	50			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P62280-53-unknown	GTYIDK...	53		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6116
P62280-72-unknown	ILSGVV...	72		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10131
P62280-80-unknown	MKMQRT...	80		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000471873
P62280-124-unknown	DIVTVG...	124		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19261
P62280-124-unknown	DIVTVG...	124		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17785

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...IQTERA	8	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10130
...KKRVLL	24	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14254
...VLLGET	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11769
...ETGKEK	31	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14255
...KEAIEG	52	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6116
...SIRGRI	71	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10131
...SPCFRD	118	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000470447
...DVQIGD	123	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19261
...DVQIGD	123	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17785
...QFQKF	158	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...QFQKF	158		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...QFQKF	158		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	8	TERA.\|.AYQK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	24	RVLL.\|.LGET	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	27	LGET.\|.TGKE	inferred from experiment	unknown	MEROPS		Merops GRAB_HUMAN -> RS11_HUMAN @27
GRAB_HUMAN	27	LGET.\|.TGKE	inferred from experiment	unknown	MEROPS	Gevaert K	Plasman K et al.:Probing the efficiency of prote... (S01.010)	21048194,
GRAM_HUMAN	31	GKEK.\|.KLPR	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATL1_HUMAN	52	AIEG.\|.GTYI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAA_HUMAN	71	RGRI.\|.ILSG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
MEP1B_HUMAN	123	QIGD.\|.DIVT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	123	QIGD.\|.DIVT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)