Q9NX24: H/ACA ribonucleoprotein complex subunit 2

General Information

Protein names	- H/ACA ribonucleoprotein complex subunit 2 - Nucleolar protein family A member 2 - snoRNP protein NHP2
Gene names	NHP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NX24

7 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTKIKADPDG PEAQAEACSG ERTYQELLVN QNPIAQPLAS RRLTRKLYKC IKKAVKQKQI
        70         80         90        100        110        120
RRGVKEVQKF VNKGEKGIMV LAGDTLPIEV YCHLPVMCED RNLPYVYIPS KTDLGAAAGS
       130        140        150
KRPTCVIMVK PHEEYQEAYD ECLEEVQSLP LPL

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NX24-1-unknown	MTKIKA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NX24-1-acetylation	MTKIKA...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9NX24-2-unknown	TKIKAD...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9NX24-2-unknown	TKIKAD...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9NX24-10-unknown	GPEAQA...	10		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2329
Q9NX24-23-unknown	TYQELL...	23		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10565
Q9NX24-106-	VYIPSK...	106			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9NX24-106-unknown	VYIPSK...	106			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KADPDG	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2329
...CSGERT	22	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10565
...LPLPL	153	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	9	DPDG.\|.GPEA	inferred from experiment	unknown	MEROPS		Merops CASP3_HUMAN -> NHP2_HUMAN @9
GRAA_HUMAN	22	GERT.\|.TYQE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)