P68431: Histone H3.1

General Information

Protein names	- Histone H3.1 - Histone H3/a - Histone H3/b - Histone H3/c - Histone H3/d - Histone H3/f - Histone H3/h - Histone H3/i - Histone H3/j - Histone H3/k - Histone H3/l
Gene names	HIST1H3J
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P68431

7 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MARTKQTARK STGGKAPRKQ LATKAARKSA PATGGVKKPH RYRPGTVALR EIRRYQKSTE
        70         80         90        100        110        120
LLIRKLPFQR LVREIAQDFK TDLRFQSSAV MALQEACEAY LVGLFEDTNL CAIHAKRVTI
       130
MPKDIQLARR IRGERA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P68431-2-unknown	ARTKQT...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P68431-10-	KSTGGK...	10		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P68431-28-	KSAPAT...	28		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P68431-28-	KSAPAT...	28		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P68431-28-unknown	KSAPAT...	28	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10164
P68431-29-	SAPATG...	29		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P68431-29-	SAPATG...	29		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P68431-29-	SAPATG...	29		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P68431-29-	SAPATG...	29		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P68431-29-unknown	SAPATG...	29	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10165
P68431-55-	YQKSTE...	55		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P68431-55-	YQKSTE...	55		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P68431-55-	YQKSTE...	55		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P68431-55-	YQKSTE...	55		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P68431-55-	YQKSTE...	55		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P68431-55-	YQKSTE...	55		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TKAARK	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10164
...KAARKS	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10165
...RGERA	136	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	27	AARK.\|.KSAP	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	28	ARKS.\|.SAPA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)